Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs

Detalhes bibliográficos
Autor(a) principal: Malcher, José Carlos Rodrigues
Data de Publicação: 2012
Outros Autores: de Oliveira, Érica Landy, de Castro, Larissa Renata Silva, da Silva, Paula Barbosa, Ramos, Érica Lorena Mendonça, Fernandes, Julio Israel
Tipo de documento: Artigo
Idioma: por
Título da fonte: Brazilian Journal of Veterinary Medicine
Texto Completo: https://rbmv.org/BJVM/article/view/757
Resumo: ABSTRACT. Malcher J.C.R., de Oliveira E.L., de Castro L.R.S., da Silva P.B., Ramos E.L.M. & Fernandes J.I. [Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs]. Eficácia do nim (Azadirachta indica) no tratamento de otite externa por Malassezia sp. em cães. Revista Brasileira de Medicina Veterinária, 34(Supl. 1):89-94, 2012. Faculdade de Medicina Veterinária, Universidade Federal do Pará, BR-316, Km 61, Castanhal, PA 68740-970, Brasil. E-mail: vetjulio@yahoo.com.br The aim of this study was to evaluate the efficacy of Neem (Azadirachta indica) oil and 10% Neem oil emulsion in the treatment of fungal otitis caused by Malassezia sp. on naturally infected dogs. Thirty-six animals of different breeds and ages were divided into three groups of 12 animals each. Group A, control group, was treated daily with saline solution by spraying. Group B was treated with 100% Neem oil by instilling 0.5 mL in each ear daily. Group C was treated using a 10% Neem oil emulsion at a dose of 3 mL/kg per ear, daily. The treatment duration was 21 days. Animals were evaluated daily for appearance of product-related side effects. Dogs were examined by bilateral cytology on days +3, +7, +14, +21, +28, and + 35 post-treatment to evaluate efficacy of treatments. No adverse reactions were seen in any of the treated animals. Despite the clinical improvement of all treated animals, the Neem oil and the 10% Neem oil emulsion were not efficacious in the treatment of ear infections caused by Malassezia sp.
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spelling Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogsEFICÁCIA DO NIM (Azadirachta indica) NO TRATAMENTO DE OTITE EXTERNA POR Malassezia sp. EM CÃESOtite externaTratamentoFitoterapiaNimAzadirachta indicaOtitisTreatmentPhytotherapyNeemAzadirachta indicaABSTRACT. Malcher J.C.R., de Oliveira E.L., de Castro L.R.S., da Silva P.B., Ramos E.L.M. & Fernandes J.I. [Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs]. Eficácia do nim (Azadirachta indica) no tratamento de otite externa por Malassezia sp. em cães. Revista Brasileira de Medicina Veterinária, 34(Supl. 1):89-94, 2012. Faculdade de Medicina Veterinária, Universidade Federal do Pará, BR-316, Km 61, Castanhal, PA 68740-970, Brasil. E-mail: vetjulio@yahoo.com.br The aim of this study was to evaluate the efficacy of Neem (Azadirachta indica) oil and 10% Neem oil emulsion in the treatment of fungal otitis caused by Malassezia sp. on naturally infected dogs. Thirty-six animals of different breeds and ages were divided into three groups of 12 animals each. Group A, control group, was treated daily with saline solution by spraying. Group B was treated with 100% Neem oil by instilling 0.5 mL in each ear daily. Group C was treated using a 10% Neem oil emulsion at a dose of 3 mL/kg per ear, daily. The treatment duration was 21 days. Animals were evaluated daily for appearance of product-related side effects. Dogs were examined by bilateral cytology on days +3, +7, +14, +21, +28, and + 35 post-treatment to evaluate efficacy of treatments. No adverse reactions were seen in any of the treated animals. Despite the clinical improvement of all treated animals, the Neem oil and the 10% Neem oil emulsion were not efficacious in the treatment of ear infections caused by Malassezia sp.O objetivo do estudo foi verificar a eficácia do óleo de Nim (Azadirachta indica) e a sua emulsão a 10%, no tratamento das otites fúngicas causadas por Malasseziasp. em cães naturalmente infectados. Foram utilizados 36 animais de diferentes raças e idades, divididos em três grupos com 12 animais cada. O grupo A, grupo controle, foi tratado com solução fisiológica diariamente com auxílio de borrifador. O grupo B foi tratado com óleo de Nim na concentração de 100%, instilando-se 0,5 mL em cada conduto auditivo a cada 24 horas. Já o Grupo C foi medicado utilizando-se emulsão aquosa de Nim a 10%, na dose de 3mL/kg, uma vez ao dia. A duração dos tratamentos foi de 21 dias. Foram realizadas observações diárias nos animais para verificar possíveis reações adversas ao produto. A avaliação da eficácia dos tratamentos foi feita através de citologia bilateral nos dias +3, +7, +14, +21, +28 e + 35. Não foram observadas reações adversas ao produto nos animais tratados. Apesar da evidente melhora clínica dos animais tratados, o óleo de Nim e sua emulsão a 10% não foram eficazes no tratamento das otites por Malassezia sp.Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.2012-12-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpeer reviewedAvaliado pelos paresapplication/pdfhttps://rbmv.org/BJVM/article/view/757Brazilian Journal of Veterinary Medicine; Vol. 34 No. Supl.1 (2012); 89-94Revista Brasileira de Medicina Veterinária; v. 34 n. Supl.1 (2012); 89-942527-21790100-2430reponame:Brazilian Journal of Veterinary Medicineinstname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)instacron:SBMVporhttps://rbmv.org/BJVM/article/view/757/617Malcher, José Carlos Rodriguesde Oliveira, Érica Landyde Castro, Larissa Renata Silvada Silva, Paula Barbosade Castro, Larissa Renata Silvada Silva, Paula BarbosaRamos, Érica Lorena MendonçaFernandes, Julio Israelinfo:eu-repo/semantics/openAccess2020-12-23T17:29:50Zoai:ojs.rbmv.org:article/757Revistahttps://rbmv.org/BJVMONGhttps://rbmv.org/BJVM/oaicontato.rbmv@gmail.com2527-21790100-2430opendoar:2020-12-23T17:29:50Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)false
dc.title.none.fl_str_mv Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs
EFICÁCIA DO NIM (Azadirachta indica) NO TRATAMENTO DE OTITE EXTERNA POR Malassezia sp. EM CÃES
title Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs
spellingShingle Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs
Malcher, José Carlos Rodrigues
Otite externa
Tratamento
Fitoterapia
Nim
Azadirachta indica
Otitis
Treatment
Phytotherapy
Neem
Azadirachta indica
title_short Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs
title_full Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs
title_fullStr Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs
title_full_unstemmed Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs
title_sort Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs
author Malcher, José Carlos Rodrigues
author_facet Malcher, José Carlos Rodrigues
de Oliveira, Érica Landy
de Castro, Larissa Renata Silva
da Silva, Paula Barbosa
Ramos, Érica Lorena Mendonça
Fernandes, Julio Israel
author_role author
author2 de Oliveira, Érica Landy
de Castro, Larissa Renata Silva
da Silva, Paula Barbosa
Ramos, Érica Lorena Mendonça
Fernandes, Julio Israel
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Malcher, José Carlos Rodrigues
de Oliveira, Érica Landy
de Castro, Larissa Renata Silva
da Silva, Paula Barbosa
de Castro, Larissa Renata Silva
da Silva, Paula Barbosa
Ramos, Érica Lorena Mendonça
Fernandes, Julio Israel
dc.subject.por.fl_str_mv Otite externa
Tratamento
Fitoterapia
Nim
Azadirachta indica
Otitis
Treatment
Phytotherapy
Neem
Azadirachta indica
topic Otite externa
Tratamento
Fitoterapia
Nim
Azadirachta indica
Otitis
Treatment
Phytotherapy
Neem
Azadirachta indica
description ABSTRACT. Malcher J.C.R., de Oliveira E.L., de Castro L.R.S., da Silva P.B., Ramos E.L.M. & Fernandes J.I. [Efficacy of neem (Azadirachta indica) in the treatment of Malassezia sp. otitis externa on dogs]. Eficácia do nim (Azadirachta indica) no tratamento de otite externa por Malassezia sp. em cães. Revista Brasileira de Medicina Veterinária, 34(Supl. 1):89-94, 2012. Faculdade de Medicina Veterinária, Universidade Federal do Pará, BR-316, Km 61, Castanhal, PA 68740-970, Brasil. E-mail: vetjulio@yahoo.com.br The aim of this study was to evaluate the efficacy of Neem (Azadirachta indica) oil and 10% Neem oil emulsion in the treatment of fungal otitis caused by Malassezia sp. on naturally infected dogs. Thirty-six animals of different breeds and ages were divided into three groups of 12 animals each. Group A, control group, was treated daily with saline solution by spraying. Group B was treated with 100% Neem oil by instilling 0.5 mL in each ear daily. Group C was treated using a 10% Neem oil emulsion at a dose of 3 mL/kg per ear, daily. The treatment duration was 21 days. Animals were evaluated daily for appearance of product-related side effects. Dogs were examined by bilateral cytology on days +3, +7, +14, +21, +28, and + 35 post-treatment to evaluate efficacy of treatments. No adverse reactions were seen in any of the treated animals. Despite the clinical improvement of all treated animals, the Neem oil and the 10% Neem oil emulsion were not efficacious in the treatment of ear infections caused by Malassezia sp.
publishDate 2012
dc.date.none.fl_str_mv 2012-12-15
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
peer reviewed
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbmv.org/BJVM/article/view/757
url https://rbmv.org/BJVM/article/view/757
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbmv.org/BJVM/article/view/757/617
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.
publisher.none.fl_str_mv Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Medicine; Vol. 34 No. Supl.1 (2012); 89-94
Revista Brasileira de Medicina Veterinária; v. 34 n. Supl.1 (2012); 89-94
2527-2179
0100-2430
reponame:Brazilian Journal of Veterinary Medicine
instname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
instacron:SBMV
instname_str Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
instacron_str SBMV
institution SBMV
reponame_str Brazilian Journal of Veterinary Medicine
collection Brazilian Journal of Veterinary Medicine
repository.name.fl_str_mv Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
repository.mail.fl_str_mv contato.rbmv@gmail.com
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