Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis

Detalhes bibliográficos
Autor(a) principal: Molin,Christine Zomer Dal
Data de Publicação: 2017
Outros Autores: Trevisol,Daisson José
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Jornal Brasileiro de Nefrologia
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300337
Resumo: Abstract The main causes of hypokalemia are usually evident in the clinical history of patients, with previous episodes of vomiting, diarrhea or diuretic use. However, in some patients the cause of hypokalemia can become a challenge. In such cases, two major components of the investigation must be performed: assessment of urinary excretion potassium and the acid-base status. This article presents a case report of a patient with severe persistent hypokalemia, complementary laboratory tests indicated that's it was hypomagnesaemia and hypocalciuria associated with metabolic alkalosis, and increase of thyroid hormones. Thyrotoxic periodic paralysis was included in the differential diagnosis, but evolved into euthyroid state, persisting with severe hypokalemia, which led to be diagnosed as Gitelman syndrome.
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spelling Persistent severe hypokalemia: Gitelman syndrome and differential diagnosishypokalemiaGitelman syndromehyperthyroidismhypokalemic periodic paralysisAbstract The main causes of hypokalemia are usually evident in the clinical history of patients, with previous episodes of vomiting, diarrhea or diuretic use. However, in some patients the cause of hypokalemia can become a challenge. In such cases, two major components of the investigation must be performed: assessment of urinary excretion potassium and the acid-base status. This article presents a case report of a patient with severe persistent hypokalemia, complementary laboratory tests indicated that's it was hypomagnesaemia and hypocalciuria associated with metabolic alkalosis, and increase of thyroid hormones. Thyrotoxic periodic paralysis was included in the differential diagnosis, but evolved into euthyroid state, persisting with severe hypokalemia, which led to be diagnosed as Gitelman syndrome.Sociedade Brasileira de Nefrologia2017-09-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300337Brazilian Journal of Nephrology v.39 n.3 2017reponame:Jornal Brasileiro de Nefrologiainstname:Sociedade Brasileira de Nefrologia (SBN)instacron:SBN10.5935/0101-2800.20170058info:eu-repo/semantics/openAccessMolin,Christine Zomer DalTrevisol,Daisson Joséeng2017-10-10T00:00:00Zoai:scielo:S0101-28002017000300337Revistahttp://www.bjn.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||jbn@sbn.org.br2175-82390101-2800opendoar:2017-10-10T00:00Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)false
dc.title.none.fl_str_mv Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis
title Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis
spellingShingle Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis
Molin,Christine Zomer Dal
hypokalemia
Gitelman syndrome
hyperthyroidism
hypokalemic periodic paralysis
title_short Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis
title_full Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis
title_fullStr Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis
title_full_unstemmed Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis
title_sort Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis
author Molin,Christine Zomer Dal
author_facet Molin,Christine Zomer Dal
Trevisol,Daisson José
author_role author
author2 Trevisol,Daisson José
author2_role author
dc.contributor.author.fl_str_mv Molin,Christine Zomer Dal
Trevisol,Daisson José
dc.subject.por.fl_str_mv hypokalemia
Gitelman syndrome
hyperthyroidism
hypokalemic periodic paralysis
topic hypokalemia
Gitelman syndrome
hyperthyroidism
hypokalemic periodic paralysis
description Abstract The main causes of hypokalemia are usually evident in the clinical history of patients, with previous episodes of vomiting, diarrhea or diuretic use. However, in some patients the cause of hypokalemia can become a challenge. In such cases, two major components of the investigation must be performed: assessment of urinary excretion potassium and the acid-base status. This article presents a case report of a patient with severe persistent hypokalemia, complementary laboratory tests indicated that's it was hypomagnesaemia and hypocalciuria associated with metabolic alkalosis, and increase of thyroid hormones. Thyrotoxic periodic paralysis was included in the differential diagnosis, but evolved into euthyroid state, persisting with severe hypokalemia, which led to be diagnosed as Gitelman syndrome.
publishDate 2017
dc.date.none.fl_str_mv 2017-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300337
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300337
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0101-2800.20170058
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
dc.source.none.fl_str_mv Brazilian Journal of Nephrology v.39 n.3 2017
reponame:Jornal Brasileiro de Nefrologia
instname:Sociedade Brasileira de Nefrologia (SBN)
instacron:SBN
instname_str Sociedade Brasileira de Nefrologia (SBN)
instacron_str SBN
institution SBN
reponame_str Jornal Brasileiro de Nefrologia
collection Jornal Brasileiro de Nefrologia
repository.name.fl_str_mv Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)
repository.mail.fl_str_mv ||jbn@sbn.org.br
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