Nephrotic syndrome after insect sting: a case report

• Autor(a) principal: Junqueira,Vânia
• Data de Publicação: 2020
• Outros Autores: Donato,Beatriz, Teixeira,Catarina, Mascarenhas,Maria Isabel, Silva,Isabel Costa, Almeida,Edgar
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Jornal Brasileiro de Nefrologia
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400498
• topic: Nephrotic syndrome; Nephrosis, Lipoid; Edema; Insect Bites and Stings; Pulmonary Embolism; Hypersensitivity

ABSTRACT Minimal change disease accounts for up to 25% of the cases of nephrotic syndrome in adult population. The allergic mechanism has been associated with minimal change disease and allergens have been implied, namely insect stings. We present a case report of a woman with new onset of nephrotic syndrome after a non-hymenoptera insect sting, with biopsy-proven minimal change disease, that was accompanied by a pulmonary thromboembolism process. Complete remission with glucocorticoid therapy was observed, with sustained response for 6 months after discontinuation. A new exposure to insect sting in the same geographical region and season triggered a nephrotic syndrome relapse. Subsequent avoidance of the place resulted in a sustained remission for more than 4 years.