Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome

Detalhes bibliográficos
Autor(a) principal: Bello-Marquez,Diana Carolina
Data de Publicação: 2021
Outros Autores: Nieto-Rios,John Fredy, Serna-Higuita,Lina Maria, Gonzalez-Vergara,Alfonso Jose
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Jornal Brasileiro de Nefrologia
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000300440
Resumo: Abstract Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association with nephrotic syndrome is unusual. We present here a pediatric patient diagnosed with primary atypical hemolytic-uremic syndrome associated with nephrotic syndrome who responded to eculizumab treatment.
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spelling Nephrotic syndrome associated with primary atypical hemolytic uremic syndromeAtypical Hemolytic Uremic SyndromeNephrotic SyndromeAcute Renal InjuryHypertensionComplement System ProteinsAbstract Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association with nephrotic syndrome is unusual. We present here a pediatric patient diagnosed with primary atypical hemolytic-uremic syndrome associated with nephrotic syndrome who responded to eculizumab treatment.Sociedade Brasileira de Nefrologia2021-09-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000300440Brazilian Journal of Nephrology v.43 n.3 2021reponame:Jornal Brasileiro de Nefrologiainstname:Sociedade Brasileira de Nefrologia (SBN)instacron:SBN10.1590/2175-8239-jbn-2020-0050info:eu-repo/semantics/openAccessBello-Marquez,Diana CarolinaNieto-Rios,John FredySerna-Higuita,Lina MariaGonzalez-Vergara,Alfonso Joseeng2021-11-05T00:00:00Zoai:scielo:S0101-28002021000300440Revistahttp://www.bjn.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||jbn@sbn.org.br2175-82390101-2800opendoar:2021-11-05T00:00Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)false
dc.title.none.fl_str_mv Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome
title Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome
spellingShingle Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome
Bello-Marquez,Diana Carolina
Atypical Hemolytic Uremic Syndrome
Nephrotic Syndrome
Acute Renal Injury
Hypertension
Complement System Proteins
title_short Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome
title_full Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome
title_fullStr Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome
title_full_unstemmed Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome
title_sort Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome
author Bello-Marquez,Diana Carolina
author_facet Bello-Marquez,Diana Carolina
Nieto-Rios,John Fredy
Serna-Higuita,Lina Maria
Gonzalez-Vergara,Alfonso Jose
author_role author
author2 Nieto-Rios,John Fredy
Serna-Higuita,Lina Maria
Gonzalez-Vergara,Alfonso Jose
author2_role author
author
author
dc.contributor.author.fl_str_mv Bello-Marquez,Diana Carolina
Nieto-Rios,John Fredy
Serna-Higuita,Lina Maria
Gonzalez-Vergara,Alfonso Jose
dc.subject.por.fl_str_mv Atypical Hemolytic Uremic Syndrome
Nephrotic Syndrome
Acute Renal Injury
Hypertension
Complement System Proteins
topic Atypical Hemolytic Uremic Syndrome
Nephrotic Syndrome
Acute Renal Injury
Hypertension
Complement System Proteins
description Abstract Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association with nephrotic syndrome is unusual. We present here a pediatric patient diagnosed with primary atypical hemolytic-uremic syndrome associated with nephrotic syndrome who responded to eculizumab treatment.
publishDate 2021
dc.date.none.fl_str_mv 2021-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000300440
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000300440
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/2175-8239-jbn-2020-0050
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
dc.source.none.fl_str_mv Brazilian Journal of Nephrology v.43 n.3 2021
reponame:Jornal Brasileiro de Nefrologia
instname:Sociedade Brasileira de Nefrologia (SBN)
instacron:SBN
instname_str Sociedade Brasileira de Nefrologia (SBN)
instacron_str SBN
institution SBN
reponame_str Jornal Brasileiro de Nefrologia
collection Jornal Brasileiro de Nefrologia
repository.name.fl_str_mv Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)
repository.mail.fl_str_mv ||jbn@sbn.org.br
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