Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome
Main Author: | |
---|---|
Publication Date: | 2021 |
Other Authors: | , , |
Format: | Report |
Language: | eng |
Source: | Jornal Brasileiro de Nefrologia |
Download full: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000300440 |
Summary: | Abstract Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association with nephrotic syndrome is unusual. We present here a pediatric patient diagnosed with primary atypical hemolytic-uremic syndrome associated with nephrotic syndrome who responded to eculizumab treatment. |
id |
SBN-1_cdb0988aee122f53b494d9040c1869a2 |
---|---|
oai_identifier_str |
oai:scielo:S0101-28002021000300440 |
network_acronym_str |
SBN-1 |
network_name_str |
Jornal Brasileiro de Nefrologia |
repository_id_str |
|
spelling |
Nephrotic syndrome associated with primary atypical hemolytic uremic syndromeAtypical Hemolytic Uremic SyndromeNephrotic SyndromeAcute Renal InjuryHypertensionComplement System ProteinsAbstract Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association with nephrotic syndrome is unusual. We present here a pediatric patient diagnosed with primary atypical hemolytic-uremic syndrome associated with nephrotic syndrome who responded to eculizumab treatment.Sociedade Brasileira de Nefrologia2021-09-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000300440Brazilian Journal of Nephrology v.43 n.3 2021reponame:Jornal Brasileiro de Nefrologiainstname:Sociedade Brasileira de Nefrologia (SBN)instacron:SBN10.1590/2175-8239-jbn-2020-0050info:eu-repo/semantics/openAccessBello-Marquez,Diana CarolinaNieto-Rios,John FredySerna-Higuita,Lina MariaGonzalez-Vergara,Alfonso Joseeng2021-11-05T00:00:00Zoai:scielo:S0101-28002021000300440Revistahttp://www.bjn.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||jbn@sbn.org.br2175-82390101-2800opendoar:2021-11-05T00:00Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)false |
dc.title.none.fl_str_mv |
Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome |
title |
Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome |
spellingShingle |
Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome Bello-Marquez,Diana Carolina Atypical Hemolytic Uremic Syndrome Nephrotic Syndrome Acute Renal Injury Hypertension Complement System Proteins |
title_short |
Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome |
title_full |
Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome |
title_fullStr |
Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome |
title_full_unstemmed |
Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome |
title_sort |
Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome |
author |
Bello-Marquez,Diana Carolina |
author_facet |
Bello-Marquez,Diana Carolina Nieto-Rios,John Fredy Serna-Higuita,Lina Maria Gonzalez-Vergara,Alfonso Jose |
author_role |
author |
author2 |
Nieto-Rios,John Fredy Serna-Higuita,Lina Maria Gonzalez-Vergara,Alfonso Jose |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Bello-Marquez,Diana Carolina Nieto-Rios,John Fredy Serna-Higuita,Lina Maria Gonzalez-Vergara,Alfonso Jose |
dc.subject.por.fl_str_mv |
Atypical Hemolytic Uremic Syndrome Nephrotic Syndrome Acute Renal Injury Hypertension Complement System Proteins |
topic |
Atypical Hemolytic Uremic Syndrome Nephrotic Syndrome Acute Renal Injury Hypertension Complement System Proteins |
description |
Abstract Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association with nephrotic syndrome is unusual. We present here a pediatric patient diagnosed with primary atypical hemolytic-uremic syndrome associated with nephrotic syndrome who responded to eculizumab treatment. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000300440 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021000300440 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/2175-8239-jbn-2020-0050 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Nefrologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Nefrologia |
dc.source.none.fl_str_mv |
Brazilian Journal of Nephrology v.43 n.3 2021 reponame:Jornal Brasileiro de Nefrologia instname:Sociedade Brasileira de Nefrologia (SBN) instacron:SBN |
instname_str |
Sociedade Brasileira de Nefrologia (SBN) |
instacron_str |
SBN |
institution |
SBN |
reponame_str |
Jornal Brasileiro de Nefrologia |
collection |
Jornal Brasileiro de Nefrologia |
repository.name.fl_str_mv |
Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN) |
repository.mail.fl_str_mv |
||jbn@sbn.org.br |
_version_ |
1752122066857885696 |