Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasia

Detalhes bibliográficos
Autor(a) principal: Cambruzzi,Eduardo
Data de Publicação: 2012
Outros Autores: Molinari,Alberto Salgueiro, Uchôa,Diego Mendonça, Yépez,Vanessa
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442012000400009
Resumo: Extramedullary plasmacytoma comprises 3%-5% of all plasma cell neoplasms, and approximately 80% of the cases occur in the upper respiratory tract. Primary thyroid plasmacytomas (PTP) are rare tumors. The authors report a case of PTP in a male patient with dyspnea and dysphagia. Physical examination and computerized tomography (CT) scan revealed a solid tumor affecting the thyroid gland, measuring 12 cm in its greatest dimension. Surgical biopsy was performed. Microscopy revealed a hypercellular malignant neoplasm composed of round plasmacytoid cells arranged in solid nests, which showed a positive immunoexpression for CD138, epithelial membrane antigen (AME), kappa light chains and multiple myeloma oncogene 1 (MUM1). The diagnosis of PTP was accordingly established.
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spelling Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasiaPlasmacytomaThyroid glandMultiple myelomaImmunohistochemistryExtramedullary plasmacytoma comprises 3%-5% of all plasma cell neoplasms, and approximately 80% of the cases occur in the upper respiratory tract. Primary thyroid plasmacytomas (PTP) are rare tumors. The authors report a case of PTP in a male patient with dyspnea and dysphagia. Physical examination and computerized tomography (CT) scan revealed a solid tumor affecting the thyroid gland, measuring 12 cm in its greatest dimension. Surgical biopsy was performed. Microscopy revealed a hypercellular malignant neoplasm composed of round plasmacytoid cells arranged in solid nests, which showed a positive immunoexpression for CD138, epithelial membrane antigen (AME), kappa light chains and multiple myeloma oncogene 1 (MUM1). The diagnosis of PTP was accordingly established.Sociedade Brasileira de Patologia Clínica2012-08-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442012000400009Jornal Brasileiro de Patologia e Medicina Laboratorial v.48 n.4 2012reponame:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)instname:Sociedade Brasileira de Patologia (SBP)instacron:SBP10.1590/S1676-24442012000400009info:eu-repo/semantics/openAccessCambruzzi,EduardoMolinari,Alberto SalgueiroUchôa,Diego MendonçaYépez,Vanessaeng2012-09-24T00:00:00Zoai:scielo:S1676-24442012000400009Revistahttp://www.scielo.br/jbpmlhttps://old.scielo.br/oai/scielo-oai.php||jbpml@sbpc.org.br1678-47741676-2444opendoar:2012-09-24T00:00Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) - Sociedade Brasileira de Patologia (SBP)false
dc.title.none.fl_str_mv Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasia
title Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasia
spellingShingle Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasia
Cambruzzi,Eduardo
Plasmacytoma
Thyroid gland
Multiple myeloma
Immunohistochemistry
title_short Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasia
title_full Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasia
title_fullStr Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasia
title_full_unstemmed Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasia
title_sort Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasia
author Cambruzzi,Eduardo
author_facet Cambruzzi,Eduardo
Molinari,Alberto Salgueiro
Uchôa,Diego Mendonça
Yépez,Vanessa
author_role author
author2 Molinari,Alberto Salgueiro
Uchôa,Diego Mendonça
Yépez,Vanessa
author2_role author
author
author
dc.contributor.author.fl_str_mv Cambruzzi,Eduardo
Molinari,Alberto Salgueiro
Uchôa,Diego Mendonça
Yépez,Vanessa
dc.subject.por.fl_str_mv Plasmacytoma
Thyroid gland
Multiple myeloma
Immunohistochemistry
topic Plasmacytoma
Thyroid gland
Multiple myeloma
Immunohistochemistry
description Extramedullary plasmacytoma comprises 3%-5% of all plasma cell neoplasms, and approximately 80% of the cases occur in the upper respiratory tract. Primary thyroid plasmacytomas (PTP) are rare tumors. The authors report a case of PTP in a male patient with dyspnea and dysphagia. Physical examination and computerized tomography (CT) scan revealed a solid tumor affecting the thyroid gland, measuring 12 cm in its greatest dimension. Surgical biopsy was performed. Microscopy revealed a hypercellular malignant neoplasm composed of round plasmacytoid cells arranged in solid nests, which showed a positive immunoexpression for CD138, epithelial membrane antigen (AME), kappa light chains and multiple myeloma oncogene 1 (MUM1). The diagnosis of PTP was accordingly established.
publishDate 2012
dc.date.none.fl_str_mv 2012-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442012000400009
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1676-24442012000400009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv
Sociedade Brasileira de Patologia Clínica
publisher.none.fl_str_mv
Sociedade Brasileira de Patologia Clínica
dc.source.none.fl_str_mv Jornal Brasileiro de Patologia e Medicina Laboratorial v.48 n.4 2012
reponame:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
instname:Sociedade Brasileira de Patologia (SBP)
instacron:SBP
instname_str Sociedade Brasileira de Patologia (SBP)
instacron_str SBP
institution SBP
reponame_str Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
collection Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
repository.name.fl_str_mv Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) - Sociedade Brasileira de Patologia (SBP)
repository.mail.fl_str_mv ||jbpml@sbpc.org.br
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