Invasive bladder urothelial carcinoma, plasmacytoid variant: case report

• Autor(a) principal: Oliveira,Rui Pedro C. M.
• Data de Publicação: 2016
• Outros Autores: Abrantes,Carlos Filipe C., Silva,Edgar Miguel C. T., Marinho,Carol A., Sousa,Vítor Manuel L., Castro,Lígia R. C. O. A. P.
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442016000400262
• topic: urinary bladder; transitional cell cancer; carcinoma

ABSTRACT Invasive bladder urothelial carcinoma, plasmacytoid variant is a rare entity with scarce cases reported in the literature. We report a case of a 79 years old male, subjected to transurethral resection of bladder tumor, which histological examination revealed a pT1 high-grade urothelial carcinoma. Subsequently, he underwent radical cystoprostatectomy, which showed urothelial carcinoma with lack of cohesion, plasmacytoid variant, positive for citokeratin 7 (CK7), citokeratin 20 (CK20) and trans-acting T-cell-specific transcription factor (GATA-3), and negative for E-cadherin and CD138. It is important to recognize the plasmacytoid variant of the invasive urothelial carcinoma, since it avoids a potential misdiagnosis of metastatic cancer.