Comparisons of IgA response in saliva and colostrum against oral streptococci species
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Oral Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100236 |
Resumo: | Abstract The present study compared IgA specificity against oral streptococci in colostrum and saliva samples. Sixty-two mother-and-child pairs were included; samples of colostrum (C) and saliva (MS) were collected from the mothers and saliva samples were collected from babies (BS). The specificity of IgA against Streptococcus mutans and S. mitis were analyzed by western blot. Only 30% of babies’ samples presented IgA reactivity to S. mutans, while 74 and 80% of MS and C, respectively, presented this response. IgA reactivity to S. mutans virulence antigens (Ag I/II, Gtf and GbpB) in positive samples showed differences between samples for Gtf and especially for GbpB (p < 0.05), but responses to Ag I/II were similar (p > 0.05). The positive response of Gtf-reactive IgA was different between C (90%) and MS (58%) samples (p < 0.05), but did not differ from BS (p > 0.05). GbpB was the least detected, with 48 and 26% of C and MS, and only 5% of BS samples presenting reactivity (p > 0.05). Eight percent of MS and C samples presented identical bands to SM in the same time-point. In conclusion, the differences of IgA response found between C and MS can be due to the different ways of stimulation, proliferation and transportation of IgA in those secretions. The colostrum has high levels of IgA against S. mutans virulence antigens, which could affect the installation and accumulation process of S. mutans, mainly by supplying anti-GbpB IgA to the neonate. |
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Brazilian Oral Research |
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Comparisons of IgA response in saliva and colostrum against oral streptococci speciesStreptococcus mutansColostrumSalivaImmunoglobulin AAbstract The present study compared IgA specificity against oral streptococci in colostrum and saliva samples. Sixty-two mother-and-child pairs were included; samples of colostrum (C) and saliva (MS) were collected from the mothers and saliva samples were collected from babies (BS). The specificity of IgA against Streptococcus mutans and S. mitis were analyzed by western blot. Only 30% of babies’ samples presented IgA reactivity to S. mutans, while 74 and 80% of MS and C, respectively, presented this response. IgA reactivity to S. mutans virulence antigens (Ag I/II, Gtf and GbpB) in positive samples showed differences between samples for Gtf and especially for GbpB (p < 0.05), but responses to Ag I/II were similar (p > 0.05). The positive response of Gtf-reactive IgA was different between C (90%) and MS (58%) samples (p < 0.05), but did not differ from BS (p > 0.05). GbpB was the least detected, with 48 and 26% of C and MS, and only 5% of BS samples presenting reactivity (p > 0.05). Eight percent of MS and C samples presented identical bands to SM in the same time-point. In conclusion, the differences of IgA response found between C and MS can be due to the different ways of stimulation, proliferation and transportation of IgA in those secretions. The colostrum has high levels of IgA against S. mutans virulence antigens, which could affect the installation and accumulation process of S. mutans, mainly by supplying anti-GbpB IgA to the neonate.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100236Brazilian Oral Research v.31 2017reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/1807-3107bor-2017.vol31.0039info:eu-repo/semantics/openAccessBERTOLDO,Barbara BellocchioSILVA,Camilla Beatriz daRODRIGUES,Denise Bertulucci RochaGERALDO-MARTINS,Vinicius RangelFERRIANI,Virginia Paes LemeNOGUEIRA,Ruchele Diaseng2017-05-12T00:00:00Zoai:scielo:S1806-83242017000100236Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2017-05-12T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false |
dc.title.none.fl_str_mv |
Comparisons of IgA response in saliva and colostrum against oral streptococci species |
title |
Comparisons of IgA response in saliva and colostrum against oral streptococci species |
spellingShingle |
Comparisons of IgA response in saliva and colostrum against oral streptococci species BERTOLDO,Barbara Bellocchio Streptococcus mutans Colostrum Saliva Immunoglobulin A |
title_short |
Comparisons of IgA response in saliva and colostrum against oral streptococci species |
title_full |
Comparisons of IgA response in saliva and colostrum against oral streptococci species |
title_fullStr |
Comparisons of IgA response in saliva and colostrum against oral streptococci species |
title_full_unstemmed |
Comparisons of IgA response in saliva and colostrum against oral streptococci species |
title_sort |
Comparisons of IgA response in saliva and colostrum against oral streptococci species |
author |
BERTOLDO,Barbara Bellocchio |
author_facet |
BERTOLDO,Barbara Bellocchio SILVA,Camilla Beatriz da RODRIGUES,Denise Bertulucci Rocha GERALDO-MARTINS,Vinicius Rangel FERRIANI,Virginia Paes Leme NOGUEIRA,Ruchele Dias |
author_role |
author |
author2 |
SILVA,Camilla Beatriz da RODRIGUES,Denise Bertulucci Rocha GERALDO-MARTINS,Vinicius Rangel FERRIANI,Virginia Paes Leme NOGUEIRA,Ruchele Dias |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
BERTOLDO,Barbara Bellocchio SILVA,Camilla Beatriz da RODRIGUES,Denise Bertulucci Rocha GERALDO-MARTINS,Vinicius Rangel FERRIANI,Virginia Paes Leme NOGUEIRA,Ruchele Dias |
dc.subject.por.fl_str_mv |
Streptococcus mutans Colostrum Saliva Immunoglobulin A |
topic |
Streptococcus mutans Colostrum Saliva Immunoglobulin A |
description |
Abstract The present study compared IgA specificity against oral streptococci in colostrum and saliva samples. Sixty-two mother-and-child pairs were included; samples of colostrum (C) and saliva (MS) were collected from the mothers and saliva samples were collected from babies (BS). The specificity of IgA against Streptococcus mutans and S. mitis were analyzed by western blot. Only 30% of babies’ samples presented IgA reactivity to S. mutans, while 74 and 80% of MS and C, respectively, presented this response. IgA reactivity to S. mutans virulence antigens (Ag I/II, Gtf and GbpB) in positive samples showed differences between samples for Gtf and especially for GbpB (p < 0.05), but responses to Ag I/II were similar (p > 0.05). The positive response of Gtf-reactive IgA was different between C (90%) and MS (58%) samples (p < 0.05), but did not differ from BS (p > 0.05). GbpB was the least detected, with 48 and 26% of C and MS, and only 5% of BS samples presenting reactivity (p > 0.05). Eight percent of MS and C samples presented identical bands to SM in the same time-point. In conclusion, the differences of IgA response found between C and MS can be due to the different ways of stimulation, proliferation and transportation of IgA in those secretions. The colostrum has high levels of IgA against S. mutans virulence antigens, which could affect the installation and accumulation process of S. mutans, mainly by supplying anti-GbpB IgA to the neonate. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100236 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100236 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1807-3107bor-2017.vol31.0039 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
dc.source.none.fl_str_mv |
Brazilian Oral Research v.31 2017 reponame:Brazilian Oral Research instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO) instacron:SBPQO |
instname_str |
Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
instacron_str |
SBPQO |
institution |
SBPQO |
reponame_str |
Brazilian Oral Research |
collection |
Brazilian Oral Research |
repository.name.fl_str_mv |
Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
repository.mail.fl_str_mv |
pob@edu.usp.br||bor@sbpqo.org.br |
_version_ |
1750318325272936448 |