Coumarins and xanthones from the seeds of Mammea siamensis
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000500031 |
Resumo: | A new coumarin, mammea E/BB cyclo D (1), together with five known compounds, mammea E/BA cyclo D (2), suragin C (3), therapin B (4), 1,7-dihydroxyxanthone (5) and 1-hydroxy-5-methoxyxanthone (6), were isolated from the seeds of Mammea siamensis. Their structures were characterized using 1D and 2D NMR spectral data. Suragin C and therapin B showed cytotoxic activity against breast adenocarcinoma (MCF-7), human cervical cancer (HeLa), colon cancer (HT-29) and human oral cancer (KB). |
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Coumarins and xanthones from the seeds of Mammea siamensismammea E/BB cyclo Dcytotoxic activityMammea siamensisguttiferraeA new coumarin, mammea E/BB cyclo D (1), together with five known compounds, mammea E/BA cyclo D (2), suragin C (3), therapin B (4), 1,7-dihydroxyxanthone (5) and 1-hydroxy-5-methoxyxanthone (6), were isolated from the seeds of Mammea siamensis. Their structures were characterized using 1D and 2D NMR spectral data. Suragin C and therapin B showed cytotoxic activity against breast adenocarcinoma (MCF-7), human cervical cancer (HeLa), colon cancer (HT-29) and human oral cancer (KB).Sociedade Brasileira de Química2007-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000500031Journal of the Brazilian Chemical Society v.18 n.5 2007reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532007000500031info:eu-repo/semantics/openAccessLaphookhieo,SuratPromnart,PhunrawieSyers,John KeithKanjana-Opas,AkkharawitPonglimanont,ChanitaKaralai,Chatchanokeng2007-10-25T00:00:00Zoai:scielo:S0103-50532007000500031Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2007-10-25T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Coumarins and xanthones from the seeds of Mammea siamensis |
title |
Coumarins and xanthones from the seeds of Mammea siamensis |
spellingShingle |
Coumarins and xanthones from the seeds of Mammea siamensis Laphookhieo,Surat mammea E/BB cyclo D cytotoxic activity Mammea siamensis guttiferrae |
title_short |
Coumarins and xanthones from the seeds of Mammea siamensis |
title_full |
Coumarins and xanthones from the seeds of Mammea siamensis |
title_fullStr |
Coumarins and xanthones from the seeds of Mammea siamensis |
title_full_unstemmed |
Coumarins and xanthones from the seeds of Mammea siamensis |
title_sort |
Coumarins and xanthones from the seeds of Mammea siamensis |
author |
Laphookhieo,Surat |
author_facet |
Laphookhieo,Surat Promnart,Phunrawie Syers,John Keith Kanjana-Opas,Akkharawit Ponglimanont,Chanita Karalai,Chatchanok |
author_role |
author |
author2 |
Promnart,Phunrawie Syers,John Keith Kanjana-Opas,Akkharawit Ponglimanont,Chanita Karalai,Chatchanok |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Laphookhieo,Surat Promnart,Phunrawie Syers,John Keith Kanjana-Opas,Akkharawit Ponglimanont,Chanita Karalai,Chatchanok |
dc.subject.por.fl_str_mv |
mammea E/BB cyclo D cytotoxic activity Mammea siamensis guttiferrae |
topic |
mammea E/BB cyclo D cytotoxic activity Mammea siamensis guttiferrae |
description |
A new coumarin, mammea E/BB cyclo D (1), together with five known compounds, mammea E/BA cyclo D (2), suragin C (3), therapin B (4), 1,7-dihydroxyxanthone (5) and 1-hydroxy-5-methoxyxanthone (6), were isolated from the seeds of Mammea siamensis. Their structures were characterized using 1D and 2D NMR spectral data. Suragin C and therapin B showed cytotoxic activity against breast adenocarcinoma (MCF-7), human cervical cancer (HeLa), colon cancer (HT-29) and human oral cancer (KB). |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000500031 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000500031 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-50532007000500031 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.18 n.5 2007 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318168211980288 |