Development of a Selective and Sensitive Sensor for Urate Determination Based on Tris(1,10-phenantroline)copper(II) Bis(tetracyanoquinodimethanide) Adsorbed on Carbon Nanotubes

• Autor(a) principal: Pimentel,Dilton M.
• Data de Publicação: 2015
• Outros Autores: Oliveira,Fernando M. de, Santos,Wallans T. P. dos, Kubota,Lauro T., Damos,Flávio S., Luz,Rita C. S.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Journal of the Brazilian Chemical Society (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015001002035
• topic: Cu(phen)3(TCNQ)2; functionalized carbon nanotubes; urate

The present work describes the development of a selective electrochemical sensor for urate based on tris(1,10-phenantroline)copper(II) bis(tetracyanoquinodimethanide) (Cu(phen)3(TCNQ)2) adsorbed on multi-walled carbon nanotubes (CNT). The composite material was characterized by infrared spectroscopy, scanning electron microscopy, and electrochemical impedance spectroscopy. The composite material showed an excellent electrocatalytic activity toward oxidation of urate. The heterogeneous charge transfer rate constant (k’) between the analyte and the sensor was determined using linear sweep voltammetry experiments. The composite material shows a linear range from 5 up to 2500 µmol L-1 with limit of detection of 1.05 µmol L-1 and limit of quantification of 3.50 µmol L-1. The high sensitivity and selectivity of the sensor for urate was sufficient for its determination in biological fluids. Finally, the proposed sensor was successfully applied in urine samples.