Sesquiterpenoids from Nectandra megapotamica (Lauraceae)

Detalhes bibliográficos
Autor(a) principal: Oliveira,Carolina Q.
Data de Publicação: 2017
Outros Autores: Morandini,Liziane B., Pedroso,Marcelo, T. Neto,Alexandre, Silva,Ubiratan F., Mostardeiro,Marco A., Dalcol,Ionara I., Morel,Ademir F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000100021
Resumo: Five sesquiterpenoid oxides, named nectandrene A, B, C, D, and E, were isolated from the essential oil of the leaves of Nectandra megapotamica. Their structures were elucidated by spectroscopic analysis, and the relative configurations were proposed by their nuclear Overhauser effect (NOESY) spectrum. Three of these isolated compounds displayed significant antimicrobial activity; the compound most active had minimal inhibitory concentration (MIC) values between 3.12 and 25.0 μg mL-1 against some tested bacteria, and antifungal activity with MIC values between 12.5 and 25.0 μg mL-1.
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spelling Sesquiterpenoids from Nectandra megapotamica (Lauraceae)Nectandra megapotamicaLauraceaesesquiterpenoid spectroscopic analysisantimicrobial activityFive sesquiterpenoid oxides, named nectandrene A, B, C, D, and E, were isolated from the essential oil of the leaves of Nectandra megapotamica. Their structures were elucidated by spectroscopic analysis, and the relative configurations were proposed by their nuclear Overhauser effect (NOESY) spectrum. Three of these isolated compounds displayed significant antimicrobial activity; the compound most active had minimal inhibitory concentration (MIC) values between 3.12 and 25.0 μg mL-1 against some tested bacteria, and antifungal activity with MIC values between 12.5 and 25.0 μg mL-1.Sociedade Brasileira de Química2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000100021Journal of the Brazilian Chemical Society v.28 n.1 2017reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0103-5053.20160141info:eu-repo/semantics/openAccessOliveira,Carolina Q.Morandini,Liziane B.Pedroso,MarceloT. Neto,AlexandreSilva,Ubiratan F.Mostardeiro,Marco A.Dalcol,Ionara I.Morel,Ademir F.eng2017-01-05T00:00:00Zoai:scielo:S0103-50532017000100021Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2017-01-05T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Sesquiterpenoids from Nectandra megapotamica (Lauraceae)
title Sesquiterpenoids from Nectandra megapotamica (Lauraceae)
spellingShingle Sesquiterpenoids from Nectandra megapotamica (Lauraceae)
Oliveira,Carolina Q.
Nectandra megapotamica
Lauraceae
sesquiterpenoid spectroscopic analysis
antimicrobial activity
title_short Sesquiterpenoids from Nectandra megapotamica (Lauraceae)
title_full Sesquiterpenoids from Nectandra megapotamica (Lauraceae)
title_fullStr Sesquiterpenoids from Nectandra megapotamica (Lauraceae)
title_full_unstemmed Sesquiterpenoids from Nectandra megapotamica (Lauraceae)
title_sort Sesquiterpenoids from Nectandra megapotamica (Lauraceae)
author Oliveira,Carolina Q.
author_facet Oliveira,Carolina Q.
Morandini,Liziane B.
Pedroso,Marcelo
T. Neto,Alexandre
Silva,Ubiratan F.
Mostardeiro,Marco A.
Dalcol,Ionara I.
Morel,Ademir F.
author_role author
author2 Morandini,Liziane B.
Pedroso,Marcelo
T. Neto,Alexandre
Silva,Ubiratan F.
Mostardeiro,Marco A.
Dalcol,Ionara I.
Morel,Ademir F.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira,Carolina Q.
Morandini,Liziane B.
Pedroso,Marcelo
T. Neto,Alexandre
Silva,Ubiratan F.
Mostardeiro,Marco A.
Dalcol,Ionara I.
Morel,Ademir F.
dc.subject.por.fl_str_mv Nectandra megapotamica
Lauraceae
sesquiterpenoid spectroscopic analysis
antimicrobial activity
topic Nectandra megapotamica
Lauraceae
sesquiterpenoid spectroscopic analysis
antimicrobial activity
description Five sesquiterpenoid oxides, named nectandrene A, B, C, D, and E, were isolated from the essential oil of the leaves of Nectandra megapotamica. Their structures were elucidated by spectroscopic analysis, and the relative configurations were proposed by their nuclear Overhauser effect (NOESY) spectrum. Three of these isolated compounds displayed significant antimicrobial activity; the compound most active had minimal inhibitory concentration (MIC) values between 3.12 and 25.0 μg mL-1 against some tested bacteria, and antifungal activity with MIC values between 12.5 and 25.0 μg mL-1.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000100021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000100021
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0103-5053.20160141
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.28 n.1 2017
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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