Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties

Detalhes bibliográficos
Autor(a) principal: Moreira,Leonardo M.
Data de Publicação: 2009
Outros Autores: Lima,Adriana, Soares,Rafael R. S., Batistela,Vagner R., Gerola,Adriana P., Hioka,Noboru, Bonacin,Juliano A., Severino,Divinomar, Baptista,Mauricio S., Machado,Antônio E. da Hora, Rodrigues,Máira R., Codognoto,Lúcia, Oliveira,Hueder P. M. de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009000900013
Resumo: In this study the role of different metal centers (magnesium, zinc and copper) on the enhancement of the hydrophilic character of metallochlorophylls, was evaluated. The solvatochromism as well as the aggregation process for these compounds in water/ethanol mixtures at different volume ratios were evaluated using Fluorescence, and Resonant Light Scattering (RLS) measurements, aiming to characterize the behavior of these compounds. Independently on the studied metallochlorophyll, the presence of at least 60% of water results in a considerable increase in the fluorescence emission, probably a direct consequence of a lower aggregation of these compounds, which is confirmed by the results from RLS measurements. Additionally, the results suggest that magnesium and zinc chlorophyll should be promising phototherapeutic agents for Photodynamic Therapy.
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spelling Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation propertiesfluorescence spectroscopyresonant light scatteringmetallochlorophyllsphotodynamic therapyIn this study the role of different metal centers (magnesium, zinc and copper) on the enhancement of the hydrophilic character of metallochlorophylls, was evaluated. The solvatochromism as well as the aggregation process for these compounds in water/ethanol mixtures at different volume ratios were evaluated using Fluorescence, and Resonant Light Scattering (RLS) measurements, aiming to characterize the behavior of these compounds. Independently on the studied metallochlorophyll, the presence of at least 60% of water results in a considerable increase in the fluorescence emission, probably a direct consequence of a lower aggregation of these compounds, which is confirmed by the results from RLS measurements. Additionally, the results suggest that magnesium and zinc chlorophyll should be promising phototherapeutic agents for Photodynamic Therapy.Sociedade Brasileira de Química2009-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009000900013Journal of the Brazilian Chemical Society v.20 n.9 2009reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532009000900013info:eu-repo/semantics/openAccessMoreira,Leonardo M.Lima,AdrianaSoares,Rafael R. S.Batistela,Vagner R.Gerola,Adriana P.Hioka,NoboruBonacin,Juliano A.Severino,DivinomarBaptista,Mauricio S.Machado,Antônio E. da HoraRodrigues,Máira R.Codognoto,LúciaOliveira,Hueder P. M. deeng2011-10-14T00:00:00Zoai:scielo:S0103-50532009000900013Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2011-10-14T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties
title Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties
spellingShingle Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties
Moreira,Leonardo M.
fluorescence spectroscopy
resonant light scattering
metallochlorophylls
photodynamic therapy
title_short Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties
title_full Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties
title_fullStr Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties
title_full_unstemmed Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties
title_sort Metallochlorophylls of magnesium, copper and zinc: evaluation of the influence of the first coordination sphere on their solvatochromism and aggregation properties
author Moreira,Leonardo M.
author_facet Moreira,Leonardo M.
Lima,Adriana
Soares,Rafael R. S.
Batistela,Vagner R.
Gerola,Adriana P.
Hioka,Noboru
Bonacin,Juliano A.
Severino,Divinomar
Baptista,Mauricio S.
Machado,Antônio E. da Hora
Rodrigues,Máira R.
Codognoto,Lúcia
Oliveira,Hueder P. M. de
author_role author
author2 Lima,Adriana
Soares,Rafael R. S.
Batistela,Vagner R.
Gerola,Adriana P.
Hioka,Noboru
Bonacin,Juliano A.
Severino,Divinomar
Baptista,Mauricio S.
Machado,Antônio E. da Hora
Rodrigues,Máira R.
Codognoto,Lúcia
Oliveira,Hueder P. M. de
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Moreira,Leonardo M.
Lima,Adriana
Soares,Rafael R. S.
Batistela,Vagner R.
Gerola,Adriana P.
Hioka,Noboru
Bonacin,Juliano A.
Severino,Divinomar
Baptista,Mauricio S.
Machado,Antônio E. da Hora
Rodrigues,Máira R.
Codognoto,Lúcia
Oliveira,Hueder P. M. de
dc.subject.por.fl_str_mv fluorescence spectroscopy
resonant light scattering
metallochlorophylls
photodynamic therapy
topic fluorescence spectroscopy
resonant light scattering
metallochlorophylls
photodynamic therapy
description In this study the role of different metal centers (magnesium, zinc and copper) on the enhancement of the hydrophilic character of metallochlorophylls, was evaluated. The solvatochromism as well as the aggregation process for these compounds in water/ethanol mixtures at different volume ratios were evaluated using Fluorescence, and Resonant Light Scattering (RLS) measurements, aiming to characterize the behavior of these compounds. Independently on the studied metallochlorophyll, the presence of at least 60% of water results in a considerable increase in the fluorescence emission, probably a direct consequence of a lower aggregation of these compounds, which is confirmed by the results from RLS measurements. Additionally, the results suggest that magnesium and zinc chlorophyll should be promising phototherapeutic agents for Photodynamic Therapy.
publishDate 2009
dc.date.none.fl_str_mv 2009-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009000900013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009000900013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532009000900013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.20 n.9 2009
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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