Rodriguesic acids, modified diketopiperazines from the gastropod mollusc Pleurobranchus areolatus

Detalhes bibliográficos
Autor(a) principal: Pereira,Fabio R.
Data de Publicação: 2014
Outros Autores: Santos,Mario F. C., Williams,David E., Andersen,Raymond J., Padula,Vinicius, Ferreira,Antonio G., Berlinck,Roberto G. S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000400022
Resumo: In the present investigation, two specimens of the nudipleuran mollusc Pleurobranchus areolatus have shown to accumulate oxidized rodriguesin A derivatives. Rodriguesic acid presents a carboxylic acid replacing the terminal methyl group of the alkyl chain of rodriguesin A. A hydroxamate group was also present on the diketopiperazine moiety of a rodriguesic acid derivative. The structures of both rodriguesic acid and of rodriguesic acid hydroxamate have been established by analysis of spectroscopic data, including their absolute configuration. Two methyl esters of the rodriguesic acids have been isolated as major compounds, but were considered to be isolation artifacts.
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spelling Rodriguesic acids, modified diketopiperazines from the gastropod mollusc Pleurobranchus areolatusnudipleuraPleurobranchusdiketopiperazinehydroxamatemolluscIn the present investigation, two specimens of the nudipleuran mollusc Pleurobranchus areolatus have shown to accumulate oxidized rodriguesin A derivatives. Rodriguesic acid presents a carboxylic acid replacing the terminal methyl group of the alkyl chain of rodriguesin A. A hydroxamate group was also present on the diketopiperazine moiety of a rodriguesic acid derivative. The structures of both rodriguesic acid and of rodriguesic acid hydroxamate have been established by analysis of spectroscopic data, including their absolute configuration. Two methyl esters of the rodriguesic acids have been isolated as major compounds, but were considered to be isolation artifacts.Sociedade Brasileira de Química2014-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000400022Journal of the Brazilian Chemical Society v.25 n.4 2014reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0103-5053.20140037info:eu-repo/semantics/openAccessPereira,Fabio R.Santos,Mario F. C.Williams,David E.Andersen,Raymond J.Padula,ViniciusFerreira,Antonio G.Berlinck,Roberto G. S.eng2014-04-22T00:00:00Zoai:scielo:S0103-50532014000400022Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2014-04-22T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Rodriguesic acids, modified diketopiperazines from the gastropod mollusc Pleurobranchus areolatus
title Rodriguesic acids, modified diketopiperazines from the gastropod mollusc Pleurobranchus areolatus
spellingShingle Rodriguesic acids, modified diketopiperazines from the gastropod mollusc Pleurobranchus areolatus
Pereira,Fabio R.
nudipleura
Pleurobranchus
diketopiperazine
hydroxamate
mollusc
title_short Rodriguesic acids, modified diketopiperazines from the gastropod mollusc Pleurobranchus areolatus
title_full Rodriguesic acids, modified diketopiperazines from the gastropod mollusc Pleurobranchus areolatus
title_fullStr Rodriguesic acids, modified diketopiperazines from the gastropod mollusc Pleurobranchus areolatus
title_full_unstemmed Rodriguesic acids, modified diketopiperazines from the gastropod mollusc Pleurobranchus areolatus
title_sort Rodriguesic acids, modified diketopiperazines from the gastropod mollusc Pleurobranchus areolatus
author Pereira,Fabio R.
author_facet Pereira,Fabio R.
Santos,Mario F. C.
Williams,David E.
Andersen,Raymond J.
Padula,Vinicius
Ferreira,Antonio G.
Berlinck,Roberto G. S.
author_role author
author2 Santos,Mario F. C.
Williams,David E.
Andersen,Raymond J.
Padula,Vinicius
Ferreira,Antonio G.
Berlinck,Roberto G. S.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira,Fabio R.
Santos,Mario F. C.
Williams,David E.
Andersen,Raymond J.
Padula,Vinicius
Ferreira,Antonio G.
Berlinck,Roberto G. S.
dc.subject.por.fl_str_mv nudipleura
Pleurobranchus
diketopiperazine
hydroxamate
mollusc
topic nudipleura
Pleurobranchus
diketopiperazine
hydroxamate
mollusc
description In the present investigation, two specimens of the nudipleuran mollusc Pleurobranchus areolatus have shown to accumulate oxidized rodriguesin A derivatives. Rodriguesic acid presents a carboxylic acid replacing the terminal methyl group of the alkyl chain of rodriguesin A. A hydroxamate group was also present on the diketopiperazine moiety of a rodriguesic acid derivative. The structures of both rodriguesic acid and of rodriguesic acid hydroxamate have been established by analysis of spectroscopic data, including their absolute configuration. Two methyl esters of the rodriguesic acids have been isolated as major compounds, but were considered to be isolation artifacts.
publishDate 2014
dc.date.none.fl_str_mv 2014-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000400022
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532014000400022
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0103-5053.20140037
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.25 n.4 2014
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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