In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase

Detalhes bibliográficos
Autor(a) principal: Gomes,Anne Caroline Candido
Data de Publicação: 2014
Outros Autores: Sampaio,Luzia da Silva, Silva,Paulo André da, Lamas,Marcelo Einicker, Sakuragui,Cassia Mônica, Barreto Junior,Cleber Bomfim, Simas,Naomi Kato, Kuster,Ricardo Machado
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014001000006
Resumo: The present study aimed to investigate the in vitro effects of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+,K+-ATPase. The Na+, K+-ATPase activity was determined by colorimetric measurement of inorganic phosphate (Pi), resulting from ATP hydrolysis. Isoschaftoside significantly decreased the renal Na+, K+-ATPase activity at the highest concentration as well as at a lower concentration. Our work suggests that isoschaftoside is a promising compound for the treatment of hypertension.
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spelling In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPaseSyngonium podophyllumAraceaeIsoschaftosideenzyme inhibitionrenal Na+, K+-ATPaseThe present study aimed to investigate the in vitro effects of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+,K+-ATPase. The Na+, K+-ATPase activity was determined by colorimetric measurement of inorganic phosphate (Pi), resulting from ATP hydrolysis. Isoschaftoside significantly decreased the renal Na+, K+-ATPase activity at the highest concentration as well as at a lower concentration. Our work suggests that isoschaftoside is a promising compound for the treatment of hypertension.Sociedade Brasileira de Química2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014001000006Química Nova v.37 n.10 2014reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0100-4042.20140257info:eu-repo/semantics/openAccessGomes,Anne Caroline CandidoSampaio,Luzia da SilvaSilva,Paulo André daLamas,Marcelo EinickerSakuragui,Cassia MônicaBarreto Junior,Cleber BomfimSimas,Naomi KatoKuster,Ricardo Machadoeng2014-11-28T00:00:00Zoai:scielo:S0100-40422014001000006Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2014-11-28T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase
title In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase
spellingShingle In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase
Gomes,Anne Caroline Candido
Syngonium podophyllum
Araceae
Isoschaftoside
enzyme inhibition
renal Na+, K+-ATPase
title_short In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase
title_full In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase
title_fullStr In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase
title_full_unstemmed In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase
title_sort In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase
author Gomes,Anne Caroline Candido
author_facet Gomes,Anne Caroline Candido
Sampaio,Luzia da Silva
Silva,Paulo André da
Lamas,Marcelo Einicker
Sakuragui,Cassia Mônica
Barreto Junior,Cleber Bomfim
Simas,Naomi Kato
Kuster,Ricardo Machado
author_role author
author2 Sampaio,Luzia da Silva
Silva,Paulo André da
Lamas,Marcelo Einicker
Sakuragui,Cassia Mônica
Barreto Junior,Cleber Bomfim
Simas,Naomi Kato
Kuster,Ricardo Machado
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gomes,Anne Caroline Candido
Sampaio,Luzia da Silva
Silva,Paulo André da
Lamas,Marcelo Einicker
Sakuragui,Cassia Mônica
Barreto Junior,Cleber Bomfim
Simas,Naomi Kato
Kuster,Ricardo Machado
dc.subject.por.fl_str_mv Syngonium podophyllum
Araceae
Isoschaftoside
enzyme inhibition
renal Na+, K+-ATPase
topic Syngonium podophyllum
Araceae
Isoschaftoside
enzyme inhibition
renal Na+, K+-ATPase
description The present study aimed to investigate the in vitro effects of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+,K+-ATPase. The Na+, K+-ATPase activity was determined by colorimetric measurement of inorganic phosphate (Pi), resulting from ATP hydrolysis. Isoschaftoside significantly decreased the renal Na+, K+-ATPase activity at the highest concentration as well as at a lower concentration. Our work suggests that isoschaftoside is a promising compound for the treatment of hypertension.
publishDate 2014
dc.date.none.fl_str_mv 2014-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014001000006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014001000006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0100-4042.20140257
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.37 n.10 2014
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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