Simple, mild, and highly efficient synthesis of 2-substituted benzimidazoles and bis-benzimidazoles

Detalhes bibliográficos
Autor(a) principal: Eren,Bilge
Data de Publicação: 2014
Outros Autores: Bekdemir,Yunus
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400011
Resumo: A new convenient method for preparation of 2-substituted benzimidazoles and bis-benzimidazoles is presented. In this method, o-phenylenediamines were condensed with bisulfite adducts of various aldehydes and di-aldehydes under neat conditions by microwave heating. The results were also compared with results of synthesis by conventional heating under reflux. Structures of the products were confirmed by infrared, ¹H- and 13C-NMR spectroscopy. Short reaction times, good yields, easy purification of products, and mild reaction conditions are the main advantages of this method.
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spelling Simple, mild, and highly efficient synthesis of 2-substituted benzimidazoles and bis-benzimidazolesbenzimidazolemicrowave heatingsynthesisA new convenient method for preparation of 2-substituted benzimidazoles and bis-benzimidazoles is presented. In this method, o-phenylenediamines were condensed with bisulfite adducts of various aldehydes and di-aldehydes under neat conditions by microwave heating. The results were also compared with results of synthesis by conventional heating under reflux. Structures of the products were confirmed by infrared, ¹H- and 13C-NMR spectroscopy. Short reaction times, good yields, easy purification of products, and mild reaction conditions are the main advantages of this method.Sociedade Brasileira de Química2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400011Química Nova v.37 n.4 2014reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0100-4042.20140096info:eu-repo/semantics/openAccessEren,BilgeBekdemir,Yunuseng2014-05-29T00:00:00Zoai:scielo:S0100-40422014000400011Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2014-05-29T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Simple, mild, and highly efficient synthesis of 2-substituted benzimidazoles and bis-benzimidazoles
title Simple, mild, and highly efficient synthesis of 2-substituted benzimidazoles and bis-benzimidazoles
spellingShingle Simple, mild, and highly efficient synthesis of 2-substituted benzimidazoles and bis-benzimidazoles
Eren,Bilge
benzimidazole
microwave heating
synthesis
title_short Simple, mild, and highly efficient synthesis of 2-substituted benzimidazoles and bis-benzimidazoles
title_full Simple, mild, and highly efficient synthesis of 2-substituted benzimidazoles and bis-benzimidazoles
title_fullStr Simple, mild, and highly efficient synthesis of 2-substituted benzimidazoles and bis-benzimidazoles
title_full_unstemmed Simple, mild, and highly efficient synthesis of 2-substituted benzimidazoles and bis-benzimidazoles
title_sort Simple, mild, and highly efficient synthesis of 2-substituted benzimidazoles and bis-benzimidazoles
author Eren,Bilge
author_facet Eren,Bilge
Bekdemir,Yunus
author_role author
author2 Bekdemir,Yunus
author2_role author
dc.contributor.author.fl_str_mv Eren,Bilge
Bekdemir,Yunus
dc.subject.por.fl_str_mv benzimidazole
microwave heating
synthesis
topic benzimidazole
microwave heating
synthesis
description A new convenient method for preparation of 2-substituted benzimidazoles and bis-benzimidazoles is presented. In this method, o-phenylenediamines were condensed with bisulfite adducts of various aldehydes and di-aldehydes under neat conditions by microwave heating. The results were also compared with results of synthesis by conventional heating under reflux. Structures of the products were confirmed by infrared, ¹H- and 13C-NMR spectroscopy. Short reaction times, good yields, easy purification of products, and mild reaction conditions are the main advantages of this method.
publishDate 2014
dc.date.none.fl_str_mv 2014-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0100-4042.20140096
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.37 n.4 2014
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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