Flavonoids and a neolignan glucoside from Guarea macrophylla (Meliaceae)

• Main Author: Pereira,Cristiane
• Publication Date: 2012
• Other Authors: Barreto Júnior,Cleber Bomfim, Kuster,Ricardo Machado, Simas,Naomi Kato, Sakuragui,Cassia Mônica, Porzel,Andrea, Wessjohann,Ludger
• Format: Article
• Language: eng
• Source: Química Nova (Online)
• Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000600010
• topic: Guarea macrophylla; dehydrodiconiferyl alcohol-4-β-D-glucoside; flavonoid glycosides

This work describes the phytochemical study of the methanol extract obtained from leaves of Guarea macrophylla, leading to the isolation and identification of three flavonoid glycosides (quercetin 3-O-β-D-glucopyranoside, quercetin 3-O-b-D-galactopyranoside, kaempferol 7-O-β-D-glucopyranoside) and a neolignan glucoside, dehydrodiconiferyl alcohol-4-β-D-glucoside. All compounds were identified by a combination of spectroscopic methods (¹H, 1D, 2D NMR, 13C and UV), ESI-MS and comparison with the literature data. This is the first report of flavonoids in the genus Guarea and of a neolignan glucoside in the Meliaceae family.