Síntese de aminoálcoois derivados do D-manitol

Detalhes bibliográficos
Autor(a) principal: Oliveira,Pedro S. M. de
Data de Publicação: 2008
Outros Autores: Ferreira,Vitor F., Souza,Marcus Vinicius N. de, Carvalho,Erika Martins de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000400013
Resumo: Aminoalcohols have found important applications in synthetic and medicinal chemistry, being used as chiral building blocks for the synthesis of many biologically active compounds. This class of compounds has been also used as chiral auxiliaries and ligands in asymmetric synthesis. Due to the importance of aminoalcohols in the treatment of several diseases, such as tuberculosis, the aim of this article is the synthesis and preliminary evaluation against tuberculosis of six aminoalcohols in 5 or 6 steps using D-mannitol as starting material, which is a useful carbohydrate employed in many syntheses.
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spelling Síntese de aminoálcoois derivados do D-manitolaminoalcoholsmannitoltuberculosisAminoalcohols have found important applications in synthetic and medicinal chemistry, being used as chiral building blocks for the synthesis of many biologically active compounds. This class of compounds has been also used as chiral auxiliaries and ligands in asymmetric synthesis. Due to the importance of aminoalcohols in the treatment of several diseases, such as tuberculosis, the aim of this article is the synthesis and preliminary evaluation against tuberculosis of six aminoalcohols in 5 or 6 steps using D-mannitol as starting material, which is a useful carbohydrate employed in many syntheses.Sociedade Brasileira de Química2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000400013Química Nova v.31 n.4 2008reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422008000400013info:eu-repo/semantics/openAccessOliveira,Pedro S. M. deFerreira,Vitor F.Souza,Marcus Vinicius N. deCarvalho,Erika Martins depor2008-06-19T00:00:00Zoai:scielo:S0100-40422008000400013Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2008-06-19T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Síntese de aminoálcoois derivados do D-manitol
title Síntese de aminoálcoois derivados do D-manitol
spellingShingle Síntese de aminoálcoois derivados do D-manitol
Oliveira,Pedro S. M. de
aminoalcohols
mannitol
tuberculosis
title_short Síntese de aminoálcoois derivados do D-manitol
title_full Síntese de aminoálcoois derivados do D-manitol
title_fullStr Síntese de aminoálcoois derivados do D-manitol
title_full_unstemmed Síntese de aminoálcoois derivados do D-manitol
title_sort Síntese de aminoálcoois derivados do D-manitol
author Oliveira,Pedro S. M. de
author_facet Oliveira,Pedro S. M. de
Ferreira,Vitor F.
Souza,Marcus Vinicius N. de
Carvalho,Erika Martins de
author_role author
author2 Ferreira,Vitor F.
Souza,Marcus Vinicius N. de
Carvalho,Erika Martins de
author2_role author
author
author
dc.contributor.author.fl_str_mv Oliveira,Pedro S. M. de
Ferreira,Vitor F.
Souza,Marcus Vinicius N. de
Carvalho,Erika Martins de
dc.subject.por.fl_str_mv aminoalcohols
mannitol
tuberculosis
topic aminoalcohols
mannitol
tuberculosis
description Aminoalcohols have found important applications in synthetic and medicinal chemistry, being used as chiral building blocks for the synthesis of many biologically active compounds. This class of compounds has been also used as chiral auxiliaries and ligands in asymmetric synthesis. Due to the importance of aminoalcohols in the treatment of several diseases, such as tuberculosis, the aim of this article is the synthesis and preliminary evaluation against tuberculosis of six aminoalcohols in 5 or 6 steps using D-mannitol as starting material, which is a useful carbohydrate employed in many syntheses.
publishDate 2008
dc.date.none.fl_str_mv 2008-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000400013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000400013
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422008000400013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.31 n.4 2008
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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