Receptores A3 da adenosina: uma nova abordagem terapêutica no câncer

Detalhes bibliográficos
Autor(a) principal: Gaspar,Alexandra
Data de Publicação: 2011
Outros Autores: Silva,Tiago, Borges,Fernanda
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000800022
Resumo: Cancer is a multi-factorial disease linked with different initiating causes, cofactors and promoters, and several types of cellular damage. Advancing knowledge on the cellular and molecular biology of the processes that regulate cell proliferation, cell differentiation and cellular responses to external signals, has provided a wealth of information about the cancer cell and how it differs from a normal one. These findings make available a number of potential targets for new therapeutic approaches. The Medicinal Chemistry artwork performed so far in the development of selective and potent adenosine receptor A3 ligands, a current cancer target, will be highlighted in this work.
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spelling Receptores A3 da adenosina: uma nova abordagem terapêutica no câncercancerAR A3ligandsCancer is a multi-factorial disease linked with different initiating causes, cofactors and promoters, and several types of cellular damage. Advancing knowledge on the cellular and molecular biology of the processes that regulate cell proliferation, cell differentiation and cellular responses to external signals, has provided a wealth of information about the cancer cell and how it differs from a normal one. These findings make available a number of potential targets for new therapeutic approaches. The Medicinal Chemistry artwork performed so far in the development of selective and potent adenosine receptor A3 ligands, a current cancer target, will be highlighted in this work.Sociedade Brasileira de Química2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000800022Química Nova v.34 n.8 2011reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422011000800022info:eu-repo/semantics/openAccessGaspar,AlexandraSilva,TiagoBorges,Fernandapor2011-10-06T00:00:00Zoai:scielo:S0100-40422011000800022Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2011-10-06T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Receptores A3 da adenosina: uma nova abordagem terapêutica no câncer
title Receptores A3 da adenosina: uma nova abordagem terapêutica no câncer
spellingShingle Receptores A3 da adenosina: uma nova abordagem terapêutica no câncer
Gaspar,Alexandra
cancer
AR A3
ligands
title_short Receptores A3 da adenosina: uma nova abordagem terapêutica no câncer
title_full Receptores A3 da adenosina: uma nova abordagem terapêutica no câncer
title_fullStr Receptores A3 da adenosina: uma nova abordagem terapêutica no câncer
title_full_unstemmed Receptores A3 da adenosina: uma nova abordagem terapêutica no câncer
title_sort Receptores A3 da adenosina: uma nova abordagem terapêutica no câncer
author Gaspar,Alexandra
author_facet Gaspar,Alexandra
Silva,Tiago
Borges,Fernanda
author_role author
author2 Silva,Tiago
Borges,Fernanda
author2_role author
author
dc.contributor.author.fl_str_mv Gaspar,Alexandra
Silva,Tiago
Borges,Fernanda
dc.subject.por.fl_str_mv cancer
AR A3
ligands
topic cancer
AR A3
ligands
description Cancer is a multi-factorial disease linked with different initiating causes, cofactors and promoters, and several types of cellular damage. Advancing knowledge on the cellular and molecular biology of the processes that regulate cell proliferation, cell differentiation and cellular responses to external signals, has provided a wealth of information about the cancer cell and how it differs from a normal one. These findings make available a number of potential targets for new therapeutic approaches. The Medicinal Chemistry artwork performed so far in the development of selective and potent adenosine receptor A3 ligands, a current cancer target, will be highlighted in this work.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000800022
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000800022
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422011000800022
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.34 n.8 2011
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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