Análise de naftoquinonas em extratos brutos de raízes de Zeyheria montana M. (bolsa-de-pastor)

• Main Author: Jácome,Rose Lisieux. R. Paiva
• Publication Date: 1999
• Other Authors: Oliveira,Alaíde Braga de, Raslan,Délio S., Müller,Andreas, Wagner,Hildebert
• Format: Article
• Language: por
• Source: Química Nova (Online)
• Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40421999000200004
• topic: Z. montana; Bignoniaceae; naphthoquinones; HPLC

Four naphthoquinones, lapachol, a-lapachone, dehydro-a-lapachone and 4-hydroxy-a-lapachone were isolated from the ethanol extract of Zeyheria montana M. roots (Bignoniaceae) and were identified by spectroscopic methods. These naphthoquinones, except 4-hydroxy-a-lapachone, were quantified by HPLC, in the crude ethanol extracts of Z. montana roots. The separation of lapachol, a-lapachone and dehydro-a-lapachone was achieved and these compounds were identified in the chromatograms by their retention times and by their on line UV-spectra. The quantification of the three naphthoquinones, in four different samples showed medium contents of 11,0 mg of lapachol, 6,1 mg of a-lapachone and 4,3 mg of dehydro-a-lapachone, in 100 mg of Z.montana roots.