INDICATION OF THE JOINT MOBILIZATION TECHNIQUE AFTER BILIRUBIN VERSUS LEPTIN ANALYSIS IN PTNB SUBMITTED TO PHOTOTHERAPY

• Autor(a) principal: Lançoni, Samira Said
• Data de Publicação: 2022
• Outros Autores: Nassif, Paulo Afonso Nunes, Sigwalt, Marcos Fabiano, Albuquerque, Jocilene Pedroso, Rocha, Bruno de Faria Melquíades da, Doubek, João Gabriel Cavazzani
• Tipo de documento: preprint
• Idioma: por
• Título da fonte: SciELO Preprints
• Texto Completo: https://preprints.scielo.org/index.php/scielo/preprint/view/4254
• topic: Unidade de terapia intensiva neonatal; Prematuridade; Leptina; Hiperbilirrubinemia; Doença metabólica óssea; Mobilização articular; Obesidade infantil; Neonatal intensive care unit; Prematurity; Leptin; Hyperbilirubinemia; Metabolic bone disease; Articular mobilization; Child obesity

Introduction: The limits for the viability of survival in preterm births have increased. Complications inherent to the immaturity of the systems lead to metabolic alterations. Physical activity programs have been applied in neonatal ICUs, seeking improvement in bone mineralization, weight gain and increase in leptin levels. Objectives: To analyze the serum levels of leptin and bilirubin in premature infants exposed to phototherapy, in order to establish a safe practice of joint mobilization. Method: Analytical, longitudinal, prospective cohort study with a sample composed of 108 parturients and their respective PTNBs arranged in 2 groups: control group 28 NBs and study group 23 NBs. The variables studied were: weight, gestational age, BMI, sex, serum levels of leptin in the placenta, serum levels of bilirubin, reticulocytes, 12 h, 24 h and rebound leptin, nutrition, body mass index. Results: Regarding weight, gestational age, BMI and sex, the sample was homogeneous. Regarding the concentration of leptin in the placenta and in the 12 h NB, there were no statistically significant differences. When the leptin concentrations were analyzed at the different evaluation moments of the study group, a statistically 3 significant difference (p<0.001) was found between all moments. Comparing assessment 2 to 2 of the study group, a statistically significant difference was found between placentas at all times. There was a trend of difference between 24 h with phototherapy and rebound, the same observed in the control group. There was no difference in leptin distributions in relation to placental time and 12 h between groups. Comparing each group with a leptin value lower than 0.1 the placental time and 12 h showed difference. There was a difference between 24 h with phototherapy and rebound. As for reticulocytes, there was a tendency to decrease in relation to the beginning/rebound (p<0.004). There was no correlation between leptin/bilirubin, leptin/reticulocytes, onset of nutrition and BMI/leptin. Conclusion: Phototherapy does not increase serum leptin levels in PTNBs, making joint mobilization a safe practice in this group.