ANTIBIOTIC PROPHYLAXIS FOR ABDOMINAL SURGERY: WHEN TO RECOMMEND? BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER.
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , |
Tipo de documento: | preprint |
Idioma: | eng |
Título da fonte: | SciELO Preprints |
Texto Completo: | https://preprints.scielo.org/index.php/scielo/preprint/view/6339 |
Resumo: | Background: Surgical antibiotic prophylaxis is an essential component of perioperative care. The use of prophylactic regimens of antibiotics is a well-established practice that is encouraged to be implemented in preoperative/perioperative protocols in order to prevent surgical site infections. Aims: To emphasize the crucial aspects of antibiotic prophylaxis in abdominal surgery. Results: Antibiotic prophylaxis is defined as the administration of antibiotics before contamination occurs, given with the intention of preventing infection by achieving tissue levels of antibiotics above the minimum inhibitory concentration at the time of surgical incision. It is indicated for clean operations with prosthetic materials or in cases where severe consequences may arise in the event of an infection. It is also suitable for all clean-contaminated and contaminated operations. The spectrum of action is determined by the pathogens present at the surgical site. Ideally, a single intravenous bolus dose should be administered within 60 minutes before the surgical incision. An additional dose should be given in case of hemorrhage or prolonged surgery, according to the half-life of the drug. Factors such as the patient's weight, history of allergies, and the likelihood of colonization by resistant bacteria should be taken into account. Compliance with institutional protocols enhances the effectiveness of antibiotic use. Conclusions: Surgical antibiotic prophylaxis is associated with reduced rates of surgical site infection, hospital stay, and morbimortality. |
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ANTIBIOTIC PROPHYLAXIS FOR ABDOMINAL SURGERY: WHEN TO RECOMMEND? BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER.Antibioticoprofilaxia em cirurgia digestiva: quando recomendar? Posicionamento do Colégio Brasileiro de Cirurgia Digestiva. AntibioticoprofilaxiaInfecção da Ferida CirúrgicaComplicações Pós-operatóriasProcedimentos Cirúrgicos do Sistema DigestórioAntibiotic ProphylaxisSurgical Wound InfectionsPostoperative ComplicationsDigestive System Surgical ProceduresBackground: Surgical antibiotic prophylaxis is an essential component of perioperative care. The use of prophylactic regimens of antibiotics is a well-established practice that is encouraged to be implemented in preoperative/perioperative protocols in order to prevent surgical site infections. Aims: To emphasize the crucial aspects of antibiotic prophylaxis in abdominal surgery. Results: Antibiotic prophylaxis is defined as the administration of antibiotics before contamination occurs, given with the intention of preventing infection by achieving tissue levels of antibiotics above the minimum inhibitory concentration at the time of surgical incision. It is indicated for clean operations with prosthetic materials or in cases where severe consequences may arise in the event of an infection. It is also suitable for all clean-contaminated and contaminated operations. The spectrum of action is determined by the pathogens present at the surgical site. Ideally, a single intravenous bolus dose should be administered within 60 minutes before the surgical incision. An additional dose should be given in case of hemorrhage or prolonged surgery, according to the half-life of the drug. Factors such as the patient's weight, history of allergies, and the likelihood of colonization by resistant bacteria should be taken into account. Compliance with institutional protocols enhances the effectiveness of antibiotic use. Conclusions: Surgical antibiotic prophylaxis is associated with reduced rates of surgical site infection, hospital stay, and morbimortality.Racional: A antibioticoprofilaxia é um componente importante dos cuidados perioperatórios. Objetivos: Abordar os principais aspectos da antibioticoprofilaxia em cirurgia digestiva. Resultados: Ela é definida como a redução da carga de bactérias no sítio operatório através da obtenção de níveis séricos de antibiótico acima da concentração inibitória mínima no momento da incisão cirúrgica. Está indicada em cirurgias limpas com próteses e nas quais a consequência de uma eventual infecção seja grave, bem como em todas as cirurgias limpas-contaminadas e contaminadas. O espectro de ação do antibiótico deve ser de acordo com a flora esperada no sítio cirúrgico e deve ser administrado 60 minutos antes da incisão, em bolus, por via endovenosa e preferencialmente em dose única. Nos casos de hemorragia importante ou cirurgias mais longas, uma nova dose pode ser administrada. O peso do paciente, a história de alergia a medicamentos e a possibilidade de colonização por bactérias multirresistentes devem ser levados em conta. A aderência a protocolos institucionais aumenta a chance de uso adequado da antibioticoprofilaxia. Conclusões: A antibioticoprofilaxia está associada à redução das taxas de infecção do sítio cirúrgico, tempo de internação e morbidade.SciELO PreprintsSciELO PreprintsSciELO Preprints2023-07-13info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/633910.1590/0102-672020230040e1758enghttps://preprints.scielo.org/index.php/scielo/article/view/6339/12107Copyright (c) 2023 Alexandre Coutinho Teixeira de Freitas, Álvaro Antonio Bandeira Ferraz, Leandro Cardoso Barchi, Ilka de Fátima Santana Ferreira Boinhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFreitas, Alexandre Coutinho Teixeira deFerraz, Álvaro Antonio BandeiraBarchi, Leandro CardosoBoin, Ilka de Fátima Santana Ferreirareponame:SciELO Preprintsinstname:Scientific Electronic Library Online (SCIELO)instacron:SCI2023-07-13T17:22:58Zoai:ops.preprints.scielo.org:preprint/6339Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2023-07-13T17:22:58SciELO Preprints - Scientific Electronic Library Online (SCIELO)false |
dc.title.none.fl_str_mv |
ANTIBIOTIC PROPHYLAXIS FOR ABDOMINAL SURGERY: WHEN TO RECOMMEND? BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER. Antibioticoprofilaxia em cirurgia digestiva: quando recomendar? Posicionamento do Colégio Brasileiro de Cirurgia Digestiva. |
title |
ANTIBIOTIC PROPHYLAXIS FOR ABDOMINAL SURGERY: WHEN TO RECOMMEND? BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER. |
spellingShingle |
ANTIBIOTIC PROPHYLAXIS FOR ABDOMINAL SURGERY: WHEN TO RECOMMEND? BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER. Freitas, Alexandre Coutinho Teixeira de Antibioticoprofilaxia Infecção da Ferida Cirúrgica Complicações Pós-operatórias Procedimentos Cirúrgicos do Sistema Digestório Antibiotic Prophylaxis Surgical Wound Infections Postoperative Complications Digestive System Surgical Procedures |
title_short |
ANTIBIOTIC PROPHYLAXIS FOR ABDOMINAL SURGERY: WHEN TO RECOMMEND? BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER. |
title_full |
ANTIBIOTIC PROPHYLAXIS FOR ABDOMINAL SURGERY: WHEN TO RECOMMEND? BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER. |
title_fullStr |
ANTIBIOTIC PROPHYLAXIS FOR ABDOMINAL SURGERY: WHEN TO RECOMMEND? BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER. |
title_full_unstemmed |
ANTIBIOTIC PROPHYLAXIS FOR ABDOMINAL SURGERY: WHEN TO RECOMMEND? BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER. |
title_sort |
ANTIBIOTIC PROPHYLAXIS FOR ABDOMINAL SURGERY: WHEN TO RECOMMEND? BRAZILIAN COLLEGE OF DIGESTIVE SURGERY POSITION PAPER. |
author |
Freitas, Alexandre Coutinho Teixeira de |
author_facet |
Freitas, Alexandre Coutinho Teixeira de Ferraz, Álvaro Antonio Bandeira Barchi, Leandro Cardoso Boin, Ilka de Fátima Santana Ferreira |
author_role |
author |
author2 |
Ferraz, Álvaro Antonio Bandeira Barchi, Leandro Cardoso Boin, Ilka de Fátima Santana Ferreira |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Freitas, Alexandre Coutinho Teixeira de Ferraz, Álvaro Antonio Bandeira Barchi, Leandro Cardoso Boin, Ilka de Fátima Santana Ferreira |
dc.subject.por.fl_str_mv |
Antibioticoprofilaxia Infecção da Ferida Cirúrgica Complicações Pós-operatórias Procedimentos Cirúrgicos do Sistema Digestório Antibiotic Prophylaxis Surgical Wound Infections Postoperative Complications Digestive System Surgical Procedures |
topic |
Antibioticoprofilaxia Infecção da Ferida Cirúrgica Complicações Pós-operatórias Procedimentos Cirúrgicos do Sistema Digestório Antibiotic Prophylaxis Surgical Wound Infections Postoperative Complications Digestive System Surgical Procedures |
description |
Background: Surgical antibiotic prophylaxis is an essential component of perioperative care. The use of prophylactic regimens of antibiotics is a well-established practice that is encouraged to be implemented in preoperative/perioperative protocols in order to prevent surgical site infections. Aims: To emphasize the crucial aspects of antibiotic prophylaxis in abdominal surgery. Results: Antibiotic prophylaxis is defined as the administration of antibiotics before contamination occurs, given with the intention of preventing infection by achieving tissue levels of antibiotics above the minimum inhibitory concentration at the time of surgical incision. It is indicated for clean operations with prosthetic materials or in cases where severe consequences may arise in the event of an infection. It is also suitable for all clean-contaminated and contaminated operations. The spectrum of action is determined by the pathogens present at the surgical site. Ideally, a single intravenous bolus dose should be administered within 60 minutes before the surgical incision. An additional dose should be given in case of hemorrhage or prolonged surgery, according to the half-life of the drug. Factors such as the patient's weight, history of allergies, and the likelihood of colonization by resistant bacteria should be taken into account. Compliance with institutional protocols enhances the effectiveness of antibiotic use. Conclusions: Surgical antibiotic prophylaxis is associated with reduced rates of surgical site infection, hospital stay, and morbimortality. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-13 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/preprint info:eu-repo/semantics/publishedVersion |
format |
preprint |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://preprints.scielo.org/index.php/scielo/preprint/view/6339 10.1590/0102-672020230040e1758 |
url |
https://preprints.scielo.org/index.php/scielo/preprint/view/6339 |
identifier_str_mv |
10.1590/0102-672020230040e1758 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://preprints.scielo.org/index.php/scielo/article/view/6339/12107 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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SciELO Preprints SciELO Preprints SciELO Preprints |
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SciELO Preprints SciELO Preprints SciELO Preprints |
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