Xylitol inhibits J774A.1 macrophage adhesion in vitro

Detalhes bibliográficos
Autor(a) principal: Ferreira,Aline Siqueira
Data de Publicação: 2011
Outros Autores: Souza,Maria Aparecida de, Raposo,Nádia Rezende Barbosa, Ferreira,Ana Paula, Silva,Silvio Silvério da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600017
Resumo: The aim of this work was to evaluate the effect of xylitol on J774A.1 macrophage adhesion. Adhesion consisted of a three-hour interval, at room temperature, followed by washing and cell incubation at 37ºC/5% CO2/ 48h. Xylitol was used to treat the cells either before (for 24h) or after the cell incubation (for 48h) at 5% as final concentration in both the situations. It was found that xylitol was effective in preventing the adhesion in both the conditions in spite of the former being 100-fold greater and significant (p < 0.001). The results pointed to an important xylitol action on macrophage adhesion, which should be further investigated as an inflammatory control.
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spelling Xylitol inhibits J774A.1 macrophage adhesion in vitroadhesionJ774A1 macrophagesxylitolThe aim of this work was to evaluate the effect of xylitol on J774A.1 macrophage adhesion. Adhesion consisted of a three-hour interval, at room temperature, followed by washing and cell incubation at 37ºC/5% CO2/ 48h. Xylitol was used to treat the cells either before (for 24h) or after the cell incubation (for 48h) at 5% as final concentration in both the situations. It was found that xylitol was effective in preventing the adhesion in both the conditions in spite of the former being 100-fold greater and significant (p < 0.001). The results pointed to an important xylitol action on macrophage adhesion, which should be further investigated as an inflammatory control.Instituto de Tecnologia do Paraná - Tecpar2011-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600017Brazilian Archives of Biology and Technology v.54 n.6 2011reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132011000600017info:eu-repo/semantics/openAccessFerreira,Aline SiqueiraSouza,Maria Aparecida deRaposo,Nádia Rezende BarbosaFerreira,Ana PaulaSilva,Silvio Silvério daeng2011-12-13T00:00:00Zoai:scielo:S1516-89132011000600017Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2011-12-13T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Xylitol inhibits J774A.1 macrophage adhesion in vitro
title Xylitol inhibits J774A.1 macrophage adhesion in vitro
spellingShingle Xylitol inhibits J774A.1 macrophage adhesion in vitro
Ferreira,Aline Siqueira
adhesion
J774A
1 macrophages
xylitol
title_short Xylitol inhibits J774A.1 macrophage adhesion in vitro
title_full Xylitol inhibits J774A.1 macrophage adhesion in vitro
title_fullStr Xylitol inhibits J774A.1 macrophage adhesion in vitro
title_full_unstemmed Xylitol inhibits J774A.1 macrophage adhesion in vitro
title_sort Xylitol inhibits J774A.1 macrophage adhesion in vitro
author Ferreira,Aline Siqueira
author_facet Ferreira,Aline Siqueira
Souza,Maria Aparecida de
Raposo,Nádia Rezende Barbosa
Ferreira,Ana Paula
Silva,Silvio Silvério da
author_role author
author2 Souza,Maria Aparecida de
Raposo,Nádia Rezende Barbosa
Ferreira,Ana Paula
Silva,Silvio Silvério da
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Ferreira,Aline Siqueira
Souza,Maria Aparecida de
Raposo,Nádia Rezende Barbosa
Ferreira,Ana Paula
Silva,Silvio Silvério da
dc.subject.por.fl_str_mv adhesion
J774A
1 macrophages
xylitol
topic adhesion
J774A
1 macrophages
xylitol
description The aim of this work was to evaluate the effect of xylitol on J774A.1 macrophage adhesion. Adhesion consisted of a three-hour interval, at room temperature, followed by washing and cell incubation at 37ºC/5% CO2/ 48h. Xylitol was used to treat the cells either before (for 24h) or after the cell incubation (for 48h) at 5% as final concentration in both the situations. It was found that xylitol was effective in preventing the adhesion in both the conditions in spite of the former being 100-fold greater and significant (p < 0.001). The results pointed to an important xylitol action on macrophage adhesion, which should be further investigated as an inflammatory control.
publishDate 2011
dc.date.none.fl_str_mv 2011-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600017
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132011000600017
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.54 n.6 2011
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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