Imaging and therapy with radionuclide labeled magnetic nanoparticles

Detalhes bibliográficos
Autor(a) principal: Ünak,Perihan
Data de Publicação: 2008
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700006
Resumo: Magnetic nanoparticles offer exciting new opportunities including the improvement of the quality of magnetic resonance imaging (MRI), hyperthermic treatment for malignant cells, site-specific drug delivery and also the recent research interest of manipulating cell membranes. The biological applications of these nanomaterials require these nanoparticles to have high magnetization values, size smaller than 20 nm, narrow particle size distribution and a special surface coating for both avoiding toxicity and allowing the coupling of biomolecules. In this review, we focus on the feasibility of radionuclide labeled magnetic nanoparticles, as drug carriers, and summarize recent advances in this field.
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spelling Imaging and therapy with radionuclide labeled magnetic nanoparticlesMagnetite Nanoparticlesradionuclideimagingtherapytargeted drug deliveryiron oxideMagnetic nanoparticles offer exciting new opportunities including the improvement of the quality of magnetic resonance imaging (MRI), hyperthermic treatment for malignant cells, site-specific drug delivery and also the recent research interest of manipulating cell membranes. The biological applications of these nanomaterials require these nanoparticles to have high magnetization values, size smaller than 20 nm, narrow particle size distribution and a special surface coating for both avoiding toxicity and allowing the coupling of biomolecules. In this review, we focus on the feasibility of radionuclide labeled magnetic nanoparticles, as drug carriers, and summarize recent advances in this field.Instituto de Tecnologia do Paraná - Tecpar2008-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700006Brazilian Archives of Biology and Technology v.51 n.spe 2008reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132008000700006info:eu-repo/semantics/openAccessÜnak,Perihaneng2009-02-20T00:00:00Zoai:scielo:S1516-89132008000700006Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2009-02-20T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Imaging and therapy with radionuclide labeled magnetic nanoparticles
title Imaging and therapy with radionuclide labeled magnetic nanoparticles
spellingShingle Imaging and therapy with radionuclide labeled magnetic nanoparticles
Ünak,Perihan
Magnetite Nanoparticles
radionuclide
imaging
therapy
targeted drug delivery
iron oxide
title_short Imaging and therapy with radionuclide labeled magnetic nanoparticles
title_full Imaging and therapy with radionuclide labeled magnetic nanoparticles
title_fullStr Imaging and therapy with radionuclide labeled magnetic nanoparticles
title_full_unstemmed Imaging and therapy with radionuclide labeled magnetic nanoparticles
title_sort Imaging and therapy with radionuclide labeled magnetic nanoparticles
author Ünak,Perihan
author_facet Ünak,Perihan
author_role author
dc.contributor.author.fl_str_mv Ünak,Perihan
dc.subject.por.fl_str_mv Magnetite Nanoparticles
radionuclide
imaging
therapy
targeted drug delivery
iron oxide
topic Magnetite Nanoparticles
radionuclide
imaging
therapy
targeted drug delivery
iron oxide
description Magnetic nanoparticles offer exciting new opportunities including the improvement of the quality of magnetic resonance imaging (MRI), hyperthermic treatment for malignant cells, site-specific drug delivery and also the recent research interest of manipulating cell membranes. The biological applications of these nanomaterials require these nanoparticles to have high magnetization values, size smaller than 20 nm, narrow particle size distribution and a special surface coating for both avoiding toxicity and allowing the coupling of biomolecules. In this review, we focus on the feasibility of radionuclide labeled magnetic nanoparticles, as drug carriers, and summarize recent advances in this field.
publishDate 2008
dc.date.none.fl_str_mv 2008-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132008000700006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.51 n.spe 2008
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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