Rats offspring exposed to Ipomoea Carnea and handling during gestation: neurochemical evaluation

Detalhes bibliográficos
Autor(a) principal: Schwarz,Aline
Data de Publicação: 2007
Outros Autores: Hosomi,Rosana Zoriki, Flório,Jorge Camilo, Bernardi,Maria Martha, Górniak,Silvana Lima, Spinosa,Helenice Souza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Archives of Biology and Technology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000300009
Resumo: The present study evaluated the central monoamine levels of male and female adult rat offspring exposed orally by gavage to 0.0, 0.7, 3.0 and 15.0 mg/kg I. carnea aqueous extract daily, from gestation day (GD) 5 to GD 21. Several alterations in the monoamine activity systems were observed. However, the major differences were noted between the 0.0 mg/kg and the no gavage control groups, showing that alterations showing that alterations were not due to the alterations to the aqueous extract. The control data showed that gavage and handling of dams were stressful enough to produce a significant decline in 3,4-dihydroxyphenylacetic acid (DOPAC) and an increase in vanilmandelic acid (VMA), indicating decreased dopamine (DA) and enhanced norepinephrine (NE) activity, respectively.
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spelling Rats offspring exposed to Ipomoea Carnea and handling during gestation: neurochemical evaluationIpomoea carneaNeurotransmitterPerinateRatsStressThe present study evaluated the central monoamine levels of male and female adult rat offspring exposed orally by gavage to 0.0, 0.7, 3.0 and 15.0 mg/kg I. carnea aqueous extract daily, from gestation day (GD) 5 to GD 21. Several alterations in the monoamine activity systems were observed. However, the major differences were noted between the 0.0 mg/kg and the no gavage control groups, showing that alterations showing that alterations were not due to the alterations to the aqueous extract. The control data showed that gavage and handling of dams were stressful enough to produce a significant decline in 3,4-dihydroxyphenylacetic acid (DOPAC) and an increase in vanilmandelic acid (VMA), indicating decreased dopamine (DA) and enhanced norepinephrine (NE) activity, respectively.Instituto de Tecnologia do Paraná - Tecpar2007-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000300009Brazilian Archives of Biology and Technology v.50 n.3 2007reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132007000300009info:eu-repo/semantics/openAccessSchwarz,AlineHosomi,Rosana ZorikiFlório,Jorge CamiloBernardi,Maria MarthaGórniak,Silvana LimaSpinosa,Helenice Souzaeng2007-08-31T00:00:00Zoai:scielo:S1516-89132007000300009Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2007-08-31T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false
dc.title.none.fl_str_mv Rats offspring exposed to Ipomoea Carnea and handling during gestation: neurochemical evaluation
title Rats offspring exposed to Ipomoea Carnea and handling during gestation: neurochemical evaluation
spellingShingle Rats offspring exposed to Ipomoea Carnea and handling during gestation: neurochemical evaluation
Schwarz,Aline
Ipomoea carnea
Neurotransmitter
Perinate
Rats
Stress
title_short Rats offspring exposed to Ipomoea Carnea and handling during gestation: neurochemical evaluation
title_full Rats offspring exposed to Ipomoea Carnea and handling during gestation: neurochemical evaluation
title_fullStr Rats offspring exposed to Ipomoea Carnea and handling during gestation: neurochemical evaluation
title_full_unstemmed Rats offspring exposed to Ipomoea Carnea and handling during gestation: neurochemical evaluation
title_sort Rats offspring exposed to Ipomoea Carnea and handling during gestation: neurochemical evaluation
author Schwarz,Aline
author_facet Schwarz,Aline
Hosomi,Rosana Zoriki
Flório,Jorge Camilo
Bernardi,Maria Martha
Górniak,Silvana Lima
Spinosa,Helenice Souza
author_role author
author2 Hosomi,Rosana Zoriki
Flório,Jorge Camilo
Bernardi,Maria Martha
Górniak,Silvana Lima
Spinosa,Helenice Souza
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Schwarz,Aline
Hosomi,Rosana Zoriki
Flório,Jorge Camilo
Bernardi,Maria Martha
Górniak,Silvana Lima
Spinosa,Helenice Souza
dc.subject.por.fl_str_mv Ipomoea carnea
Neurotransmitter
Perinate
Rats
Stress
topic Ipomoea carnea
Neurotransmitter
Perinate
Rats
Stress
description The present study evaluated the central monoamine levels of male and female adult rat offspring exposed orally by gavage to 0.0, 0.7, 3.0 and 15.0 mg/kg I. carnea aqueous extract daily, from gestation day (GD) 5 to GD 21. Several alterations in the monoamine activity systems were observed. However, the major differences were noted between the 0.0 mg/kg and the no gavage control groups, showing that alterations showing that alterations were not due to the alterations to the aqueous extract. The control data showed that gavage and handling of dams were stressful enough to produce a significant decline in 3,4-dihydroxyphenylacetic acid (DOPAC) and an increase in vanilmandelic acid (VMA), indicating decreased dopamine (DA) and enhanced norepinephrine (NE) activity, respectively.
publishDate 2007
dc.date.none.fl_str_mv 2007-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000300009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000300009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-89132007000300009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
publisher.none.fl_str_mv Instituto de Tecnologia do Paraná - Tecpar
dc.source.none.fl_str_mv Brazilian Archives of Biology and Technology v.50 n.3 2007
reponame:Brazilian Archives of Biology and Technology
instname:Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
instname_str Instituto de Tecnologia do Paraná (Tecpar)
instacron_str TECPAR
institution TECPAR
reponame_str Brazilian Archives of Biology and Technology
collection Brazilian Archives of Biology and Technology
repository.name.fl_str_mv Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)
repository.mail.fl_str_mv babt@tecpar.br||babt@tecpar.br
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