Paternal High-Fat Diet Exposure Induces Adverse Effects on Offspring Health: a Systematic Review of Animal Studies
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100903 |
Resumo: | Abstract This systematic review examined the effects of paternal exposure to a high-fat diet on the likelihood of offspring developing health consequences, including metabolic conditions. While the connection between a mother’s diet and offspring health has been well established, our understanding of whether offspring health is affected by a father’s diet remains limited. This systematic review was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) recommendations. The PubMed, Scopus, and Embase electronic databases were searched using combinations of the MESH terms: obesogenic diet, high-fat diet, cafeteria diet, paternal diet, parental diet, programming, paternal effects, and paternal programming. Sixteen studies were selected after assessing articles for eligibility criteria. The main outcomes concerning offspring health related to metabolic disorders. The offspring of fathers exposed to a high-fat diet displayed elevated gene expression and serum levels of leptin, decreased gene expression and serum levels of adiponectin, insulin resistance, glucose intolerance, hyperglycemia, hyperinsulinemia, changes in the transcriptome of pancreatic islet tissues, increased triglycerides, and increased expression of lipogenic genes. The available evidence suggests that paternal exposure to a high-fat diet may induce harmful effects on the health of offspring. |
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Paternal High-Fat Diet Exposure Induces Adverse Effects on Offspring Health: a Systematic Review of Animal Studieshigh-fat dietpaternal imprintingpaternal programmingoffspringratsmiceAbstract This systematic review examined the effects of paternal exposure to a high-fat diet on the likelihood of offspring developing health consequences, including metabolic conditions. While the connection between a mother’s diet and offspring health has been well established, our understanding of whether offspring health is affected by a father’s diet remains limited. This systematic review was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) recommendations. The PubMed, Scopus, and Embase electronic databases were searched using combinations of the MESH terms: obesogenic diet, high-fat diet, cafeteria diet, paternal diet, parental diet, programming, paternal effects, and paternal programming. Sixteen studies were selected after assessing articles for eligibility criteria. The main outcomes concerning offspring health related to metabolic disorders. The offspring of fathers exposed to a high-fat diet displayed elevated gene expression and serum levels of leptin, decreased gene expression and serum levels of adiponectin, insulin resistance, glucose intolerance, hyperglycemia, hyperinsulinemia, changes in the transcriptome of pancreatic islet tissues, increased triglycerides, and increased expression of lipogenic genes. The available evidence suggests that paternal exposure to a high-fat diet may induce harmful effects on the health of offspring.Instituto de Tecnologia do Paraná - Tecpar2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100903Brazilian Archives of Biology and Technology v.64 2021reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/1678-4324-2021190123info:eu-repo/semantics/openAccessGonçalves,Mariane dos SantosPerez,Gabriela dos SantosFerreira,Luciana de Jesus DantasSantos,Lucimeire Santana dosCordeiro,Gabriele dos SantosCouto,Ricardo DavidMedeiros,Jairza Maria Barretoeng2021-07-02T00:00:00Zoai:scielo:S1516-89132021000100903Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2021-07-02T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Paternal High-Fat Diet Exposure Induces Adverse Effects on Offspring Health: a Systematic Review of Animal Studies |
title |
Paternal High-Fat Diet Exposure Induces Adverse Effects on Offspring Health: a Systematic Review of Animal Studies |
spellingShingle |
Paternal High-Fat Diet Exposure Induces Adverse Effects on Offspring Health: a Systematic Review of Animal Studies Gonçalves,Mariane dos Santos high-fat diet paternal imprinting paternal programming offspring rats mice |
title_short |
Paternal High-Fat Diet Exposure Induces Adverse Effects on Offspring Health: a Systematic Review of Animal Studies |
title_full |
Paternal High-Fat Diet Exposure Induces Adverse Effects on Offspring Health: a Systematic Review of Animal Studies |
title_fullStr |
Paternal High-Fat Diet Exposure Induces Adverse Effects on Offspring Health: a Systematic Review of Animal Studies |
title_full_unstemmed |
Paternal High-Fat Diet Exposure Induces Adverse Effects on Offspring Health: a Systematic Review of Animal Studies |
title_sort |
Paternal High-Fat Diet Exposure Induces Adverse Effects on Offspring Health: a Systematic Review of Animal Studies |
author |
Gonçalves,Mariane dos Santos |
author_facet |
Gonçalves,Mariane dos Santos Perez,Gabriela dos Santos Ferreira,Luciana de Jesus Dantas Santos,Lucimeire Santana dos Cordeiro,Gabriele dos Santos Couto,Ricardo David Medeiros,Jairza Maria Barreto |
author_role |
author |
author2 |
Perez,Gabriela dos Santos Ferreira,Luciana de Jesus Dantas Santos,Lucimeire Santana dos Cordeiro,Gabriele dos Santos Couto,Ricardo David Medeiros,Jairza Maria Barreto |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Gonçalves,Mariane dos Santos Perez,Gabriela dos Santos Ferreira,Luciana de Jesus Dantas Santos,Lucimeire Santana dos Cordeiro,Gabriele dos Santos Couto,Ricardo David Medeiros,Jairza Maria Barreto |
dc.subject.por.fl_str_mv |
high-fat diet paternal imprinting paternal programming offspring rats mice |
topic |
high-fat diet paternal imprinting paternal programming offspring rats mice |
description |
Abstract This systematic review examined the effects of paternal exposure to a high-fat diet on the likelihood of offspring developing health consequences, including metabolic conditions. While the connection between a mother’s diet and offspring health has been well established, our understanding of whether offspring health is affected by a father’s diet remains limited. This systematic review was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) recommendations. The PubMed, Scopus, and Embase electronic databases were searched using combinations of the MESH terms: obesogenic diet, high-fat diet, cafeteria diet, paternal diet, parental diet, programming, paternal effects, and paternal programming. Sixteen studies were selected after assessing articles for eligibility criteria. The main outcomes concerning offspring health related to metabolic disorders. The offspring of fathers exposed to a high-fat diet displayed elevated gene expression and serum levels of leptin, decreased gene expression and serum levels of adiponectin, insulin resistance, glucose intolerance, hyperglycemia, hyperinsulinemia, changes in the transcriptome of pancreatic islet tissues, increased triglycerides, and increased expression of lipogenic genes. The available evidence suggests that paternal exposure to a high-fat diet may induce harmful effects on the health of offspring. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100903 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132021000100903 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1678-4324-2021190123 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.64 2021 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
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1750318280937046016 |