Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal

Detalhes bibliográficos
Autor(a) principal: Romeiro, Luiz Antonio Soares
Data de Publicação: 2003
Outros Autores: Fraga, Carlos Alberto Manssour, Barreiro, Eliezer Jesus de Lacerda
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UCB
Texto Completo: http://twingo.ucb.br:8080/jspui/handle/10869/460
https://repositorio.ucb.br:9443/jspui/handle/123456789/7674
Resumo: Depression is a widespread humor disturbance promoted mainly by depletion of biogenic neurotransmitter amines involved in the CNS synapses. Effective drug treatments for depression have been available for more than forty years. Despite its remarkable structural diversity, this paper discuss under the medicinal chemistry point of view, all different classes of “monoamine based” antidepressant drugs, emphasizing the rational design, structure-activity relationships (SAR), biotransformation and physicochemical properties related with antidepressant activity and molecular mechanism of action.
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spelling Romeiro, Luiz Antonio SoaresFraga, Carlos Alberto ManssourBarreiro, Eliezer Jesus de Lacerda2016-10-10T03:52:19Z2016-10-10T03:52:19Z2003ROMEIRO, Luiz Antonio Soares; FRAGA, Carlos Alberto Manssour; BARREIRO; Eliezer Jesus de Lacerda. Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal. Química Nova, vol.26, n.3, pp. 347-358, 2003.0100-4042http://twingo.ucb.br:8080/jspui/handle/10869/460https://repositorio.ucb.br:9443/jspui/handle/123456789/7674Depression is a widespread humor disturbance promoted mainly by depletion of biogenic neurotransmitter amines involved in the CNS synapses. Effective drug treatments for depression have been available for more than forty years. Despite its remarkable structural diversity, this paper discuss under the medicinal chemistry point of view, all different classes of “monoamine based” antidepressant drugs, emphasizing the rational design, structure-activity relationships (SAR), biotransformation and physicochemical properties related with antidepressant activity and molecular mechanism of action.Made available in DSpace on 2016-10-10T03:52:19Z (GMT). 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dc.title.pt_BR.fl_str_mv Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal
dc.title.alternative.pt_BR.fl_str_mv New therapeutical approachs for the treatment of depression: a medicinal chemistry view
title Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal
spellingShingle Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal
Romeiro, Luiz Antonio Soares
Monoamine oxidase inhibitors
Monoamine reuptake inhibitors
Serotonin receptor antagonists
title_short Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal
title_full Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal
title_fullStr Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal
title_full_unstemmed Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal
title_sort Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal
author Romeiro, Luiz Antonio Soares
author_facet Romeiro, Luiz Antonio Soares
Fraga, Carlos Alberto Manssour
Barreiro, Eliezer Jesus de Lacerda
author_role author
author2 Fraga, Carlos Alberto Manssour
Barreiro, Eliezer Jesus de Lacerda
author2_role author
author
dc.contributor.author.fl_str_mv Romeiro, Luiz Antonio Soares
Fraga, Carlos Alberto Manssour
Barreiro, Eliezer Jesus de Lacerda
dc.subject.por.fl_str_mv Monoamine oxidase inhibitors
Monoamine reuptake inhibitors
Serotonin receptor antagonists
topic Monoamine oxidase inhibitors
Monoamine reuptake inhibitors
Serotonin receptor antagonists
dc.description.abstract.por.fl_txt_mv Depression is a widespread humor disturbance promoted mainly by depletion of biogenic neurotransmitter amines involved in the CNS synapses. Effective drug treatments for depression have been available for more than forty years. Despite its remarkable structural diversity, this paper discuss under the medicinal chemistry point of view, all different classes of “monoamine based” antidepressant drugs, emphasizing the rational design, structure-activity relationships (SAR), biotransformation and physicochemical properties related with antidepressant activity and molecular mechanism of action.
dc.description.version.pt_BR.fl_txt_mv Sim
dc.description.status.pt_BR.fl_txt_mv Publicado
description Depression is a widespread humor disturbance promoted mainly by depletion of biogenic neurotransmitter amines involved in the CNS synapses. Effective drug treatments for depression have been available for more than forty years. Despite its remarkable structural diversity, this paper discuss under the medicinal chemistry point of view, all different classes of “monoamine based” antidepressant drugs, emphasizing the rational design, structure-activity relationships (SAR), biotransformation and physicochemical properties related with antidepressant activity and molecular mechanism of action.
publishDate 2003
dc.date.issued.fl_str_mv 2003
dc.date.accessioned.fl_str_mv 2016-10-10T03:52:19Z
dc.date.available.fl_str_mv 2016-10-10T03:52:19Z
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dc.identifier.citation.fl_str_mv ROMEIRO, Luiz Antonio Soares; FRAGA, Carlos Alberto Manssour; BARREIRO; Eliezer Jesus de Lacerda. Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal. Química Nova, vol.26, n.3, pp. 347-358, 2003.
dc.identifier.uri.fl_str_mv http://twingo.ucb.br:8080/jspui/handle/10869/460
https://repositorio.ucb.br:9443/jspui/handle/123456789/7674
dc.identifier.issn.none.fl_str_mv 0100-4042
identifier_str_mv ROMEIRO, Luiz Antonio Soares; FRAGA, Carlos Alberto Manssour; BARREIRO; Eliezer Jesus de Lacerda. Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal. Química Nova, vol.26, n.3, pp. 347-358, 2003.
0100-4042
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