Toxicity of ricin present in castor bean seeds

Detalhes bibliográficos
Autor(a) principal: Fonseca, Nayanna Brunna da Silva
Data de Publicação: 2014
Outros Autores: Soto-Blanco, Benito
Tipo de documento: Artigo
Idioma: por
Título da fonte: Semina. Ciências Agrárias (Online)
Texto Completo: https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15034
Resumo: The castor bean (Ricinus communis) is a bush from Euphorbiacea family cultivated for obtaining oil from the seeds. This oil has broad industrial employment, particularly for biodiesel. However, castor bean seeds exhibit a potent toxin, ricin. It is a glycoprotein with highly toxic action of inactivating ribosomes. The toxic action of ricin is due to inhibition of protein synthesis in eukaryotic cells, causing cell death. Only one molecule of ricin that enters the cytosol is able to inactivate ribosomes over 1500 per minute. Clinical signs associated with castor bean poisoning often occur in animals in a few hours after ingestion of the seeds. This paper reviews the literature on the toxic effects of ricin and techniques for preventing the poisoning.
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spelling Toxicity of ricin present in castor bean seedsToxicidade da ricina presente nas sementes de mamonaRicinus communisEuforbiaceaToxalbuminPoisonous plantToxin.Ricinus communisEuforbiáceaToxalbuminaPlanta tóxicaToxina.The castor bean (Ricinus communis) is a bush from Euphorbiacea family cultivated for obtaining oil from the seeds. This oil has broad industrial employment, particularly for biodiesel. However, castor bean seeds exhibit a potent toxin, ricin. It is a glycoprotein with highly toxic action of inactivating ribosomes. The toxic action of ricin is due to inhibition of protein synthesis in eukaryotic cells, causing cell death. Only one molecule of ricin that enters the cytosol is able to inactivate ribosomes over 1500 per minute. Clinical signs associated with castor bean poisoning often occur in animals in a few hours after ingestion of the seeds. This paper reviews the literature on the toxic effects of ricin and techniques for preventing the poisoning.A mamona (Ricinus communis) é um arbusto da família Euforbiacea cultivada para a obtenção do óleo das sementes. Este óleo apresenta amplo emprego industrial, com destaque para o biodiesel. No entanto, as sementes de mamona apresentam uma potente toxina, a ricina. Trata-se de uma glicoproteína altamente tóxica com ação inativadora de ribossomos. A ação tóxica da ricina é decorrente da inibição da síntese proteica nas células eucarióticas, ocasionando a morte celular. Apenas uma molécula de ricina que entra no citosol é capaz de inativar mais de 1500 ribossomos por minuto. Os sinais clínicos associados com a intoxicação de mamona em animais frequentemente ocorrem em algumas horas após a ingestão das sementes. Este trabalho faz uma revisão da literatura sobre os efeitos tóxicos da ricina e as técnicas para a prevenção da intoxicação. UEL2014-06-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/1503410.5433/1679-0359.2014v35n3p1415Semina: Ciências Agrárias; Vol. 35 No. 3 (2014); 1415-1424Semina: Ciências Agrárias; v. 35 n. 3 (2014); 1415-14241679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELporhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15034/pdf_339https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15034/33521https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15034/34107Fonseca, Nayanna Brunna da SilvaSoto-Blanco, Benitoinfo:eu-repo/semantics/openAccess2015-11-19T18:35:47Zoai:ojs.pkp.sfu.ca:article/15034Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2015-11-19T18:35:47Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false
dc.title.none.fl_str_mv Toxicity of ricin present in castor bean seeds
Toxicidade da ricina presente nas sementes de mamona
title Toxicity of ricin present in castor bean seeds
spellingShingle Toxicity of ricin present in castor bean seeds
Fonseca, Nayanna Brunna da Silva
Ricinus communis
Euforbiacea
Toxalbumin
Poisonous plant
Toxin.
Ricinus communis
Euforbiácea
Toxalbumina
Planta tóxica
Toxina.
title_short Toxicity of ricin present in castor bean seeds
title_full Toxicity of ricin present in castor bean seeds
title_fullStr Toxicity of ricin present in castor bean seeds
title_full_unstemmed Toxicity of ricin present in castor bean seeds
title_sort Toxicity of ricin present in castor bean seeds
author Fonseca, Nayanna Brunna da Silva
author_facet Fonseca, Nayanna Brunna da Silva
Soto-Blanco, Benito
author_role author
author2 Soto-Blanco, Benito
author2_role author
dc.contributor.author.fl_str_mv Fonseca, Nayanna Brunna da Silva
Soto-Blanco, Benito
dc.subject.por.fl_str_mv Ricinus communis
Euforbiacea
Toxalbumin
Poisonous plant
Toxin.
Ricinus communis
Euforbiácea
Toxalbumina
Planta tóxica
Toxina.
topic Ricinus communis
Euforbiacea
Toxalbumin
Poisonous plant
Toxin.
Ricinus communis
Euforbiácea
Toxalbumina
Planta tóxica
Toxina.
description The castor bean (Ricinus communis) is a bush from Euphorbiacea family cultivated for obtaining oil from the seeds. This oil has broad industrial employment, particularly for biodiesel. However, castor bean seeds exhibit a potent toxin, ricin. It is a glycoprotein with highly toxic action of inactivating ribosomes. The toxic action of ricin is due to inhibition of protein synthesis in eukaryotic cells, causing cell death. Only one molecule of ricin that enters the cytosol is able to inactivate ribosomes over 1500 per minute. Clinical signs associated with castor bean poisoning often occur in animals in a few hours after ingestion of the seeds. This paper reviews the literature on the toxic effects of ricin and techniques for preventing the poisoning.
publishDate 2014
dc.date.none.fl_str_mv 2014-06-25
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15034
10.5433/1679-0359.2014v35n3p1415
url https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15034
identifier_str_mv 10.5433/1679-0359.2014v35n3p1415
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15034/pdf_339
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15034/33521
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/15034/34107
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv UEL
publisher.none.fl_str_mv UEL
dc.source.none.fl_str_mv Semina: Ciências Agrárias; Vol. 35 No. 3 (2014); 1415-1424
Semina: Ciências Agrárias; v. 35 n. 3 (2014); 1415-1424
1679-0359
1676-546X
reponame:Semina. Ciências Agrárias (Online)
instname:Universidade Estadual de Londrina (UEL)
instacron:UEL
instname_str Universidade Estadual de Londrina (UEL)
instacron_str UEL
institution UEL
reponame_str Semina. Ciências Agrárias (Online)
collection Semina. Ciências Agrárias (Online)
repository.name.fl_str_mv Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)
repository.mail.fl_str_mv semina.agrarias@uel.br
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