BONE MARROW TRANSPLANTATION IN A DOG WITH MEDULAR APLASIA: CASE REPORT

• Main Author: Minuzzo, Tainá
• Publication Date: 2020
• Other Authors: Dutra da Silveira, Solimar
• Format: Article
• Language: eng
• Source: Revista de Ciência Veterinária e Saúde Pública
• Download full: https://periodicos.uem.br/ojs/index.php/RevCiVet/article/view/51913
• topic: hematology, pancytopenia, chronic erlichiosis.; hematologia, pancitopenia, erliquiose crônica.

Medullary aplasia is an extremely rare disorder in dogs and cats and its main feature is a hypocellular bone marrow due to the hematopoietic tissue being replaced by adipose cells, thus leading to a picture of blood pancytopenia. One of the main causes of spinal cord aplasia is known to be Erlichiacanis infection, a disease that in the chronic phase causes hypoplasia of precursors of all cell lines and this haematopoietic abnormality leads to numerous problems for the animal, such as lethargy, anorexia, weight loss and muscle weakness. Once anemia develops, hemorrhagic diathesis may also result from impairment of primary hemostasis (thrombocytopenia), as well as a predisposition to acquire secondary infections, since these patients commonly present with leukopenia. The aim of this study is to report the case of a canine patient diagnosed with spinal cord aplasia subsequent to chronic erlichiosis, where treatment with bone marrow transplantation was instituted, resulting in an improvement in hematological values ​​after the procedure.