Bioaerossóis na indústria farmacêutica

• Autor(a) principal: Ferreira, Guilherme Neves
• Data de Publicação: 2009
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações da UERJ
• Texto Completo: http://www.bdtd.uerj.br/handle/1/15713
• topic: Barrier; Microbiological contamination; Barreira; Contaminação microbiológica; CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA

This study had as objective to test a barrier against microbiological contamination in contact plates that are used in sterile pharmaceutical products clean rooms monitoring. During 2007 the tests were performed and compared with data from, 2004, 2005 and 2006, when the mentioned barrier was not used. The test environments were two clean rooms from a pharmaceutical plant located at Rio de Janeiro. In the mentioned environments the use of special garments is necessary for avoiding that particles from operators bodies, bacteria and most remain in contact with the room environment, adding risk to the sterilized products. So, it was proposed the use of undershirt between the garment and the operator skin for reducing the contact plate s contamination during the regular rooms monitoring. This undershirt was used during 2007 and the results were compared with the samples of 2004, 2005 and 2006 when the undershirt was not used. The results demonstrated that it was obtained a reduction of about 50% in relation to contaminated plates. In relation to the total number of colonies the reduction was 75% in comparison with 2004 and 2005, and 50% in comparison with 2006