Effect of LED phototherapy of three distinct wavelengths on fibroblasts on wound healing: a histological study in a rodent model

Bibliographic Details
Main Author: Sousa, Ana Paula Cavalcanti de
Publication Date: 2010
Other Authors: Santos, Jean Nunes dos, Reis Junior, João A. dos, Ramos, Thaís Andrade, Souza, José de, Cangussu, Maria Cristina Teixeira, Pinheiro, Antonio Luiz Barbosa
Format: Article
Language: eng
Source: Repositório Institucional da UFBA
Download full: http://repositorio.ufba.br/ri/handle/ri/13443
Summary: Texto completo: acesso restrito. p.547-552
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spelling Sousa, Ana Paula Cavalcanti deSantos, Jean Nunes dosReis Junior, João A. dosRamos, Thaís AndradeSouza, José deCangussu, Maria Cristina TeixeiraPinheiro, Antonio Luiz BarbosaSousa, Ana Paula Cavalcanti deSantos, Jean Nunes dosReis Junior, João A. dosRamos, Thaís AndradeSouza, José deCangussu, Maria Cristina TeixeiraPinheiro, Antonio Luiz Barbosa2013-10-31T18:20:43Z20101549-5418http://repositorio.ufba.br/ri/handle/ri/13443v. 28, n. 4Texto completo: acesso restrito. p.547-552Aim: The aim of the present investigation was to evaluate histologically fibroblastic proliferation on dorsal cutaneous wounds in a rodent model treated or not with light-emitting diodes (LEDs) of three wavelengths. Background: Fibroblasts secrete substances essential for wound healing. There are few reports of LED phototherapy on fibroblast proliferation, mainly in vivo. Animals and Methods: Following approval by the Animal Experimentation Committee of the School of Dentistry of the Federal University of Bahia, we obtained 16 young adult male Wistar rats weighing between 200 and 250 g. Under general anesthesia, one excisional wound was created on the dorsum of each animal; they were then randomly distributed into four groups of four animals each: G0, untreated control; G1, red LED (700 ± 20 nm, 15 mW, 10 J/cm2); G2, green LED (530 ± 20 nm, 8 mW, 10 J/cm2); and G3, blue LED (460 ± 20 nm, 22 mW, 10 J/cm2). The irradiation started immediately after surgery and was repeated every other day for 7 days. Animals were killed 8 days after surgery. The specimens were removed, routinely processed to wax, cut, and stained with hematoxylin/eosin (HE). Fibroblasts were scored by measuring the percentage of these cells occupying the area corresponding to wound healing on stained sections. Results: The quantitative results showed that red LED (700 ± 20 nm) and green LED (530 ± 20 nm) showed a significant increase in fibroblast numbers (p < 0.01 and p = 0.02) when compared with the control group. Conclusion: The use of green and red LED light is effective in increasing fibroblastic proliferation on rodents.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-08-22T14:06:20Z No. of bitstreams: 1 pho%2E2009%2E2605.pdf: 416523 bytes, checksum: 7a24c6e6bb7e0d9427eda1b209b9c78a (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-10-31T18:20:43Z (GMT) No. of bitstreams: 1 pho%2E2009%2E2605.pdf: 416523 bytes, checksum: 7a24c6e6bb7e0d9427eda1b209b9c78a (MD5)Made available in DSpace on 2013-10-31T18:20:43Z (GMT). No. of bitstreams: 1 pho%2E2009%2E2605.pdf: 416523 bytes, checksum: 7a24c6e6bb7e0d9427eda1b209b9c78a (MD5) Previous issue date: 2010http://dx.doi.org/10.1089/pho.2009.2605reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAEffect of LED phototherapy of three distinct wavelengths on fibroblasts on wound healing: a histological study in a rodent modelPhotomedicine and Laser Surgeryinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALpho%2E2009%2E2605.pdfpho%2E2009%2E2605.pdfapplication/pdf416523https://repositorio.ufba.br/bitstream/ri/13443/1/pho%252E2009%252E2605.pdf7a24c6e6bb7e0d9427eda1b209b9c78aMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/13443/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXTpho%2E2009%2E2605.pdf.txtpho%2E2009%2E2605.pdf.txtExtracted texttext/plain25772https://repositorio.ufba.br/bitstream/ri/13443/3/pho%252E2009%252E2605.pdf.txt501d5a338d22c2cb6039a7e78bd1e6b4MD53ri/134432022-07-05 14:03:12.695oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:12Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Effect of LED phototherapy of three distinct wavelengths on fibroblasts on wound healing: a histological study in a rodent model
dc.title.alternative.pt_BR.fl_str_mv Photomedicine and Laser Surgery
title Effect of LED phototherapy of three distinct wavelengths on fibroblasts on wound healing: a histological study in a rodent model
spellingShingle Effect of LED phototherapy of three distinct wavelengths on fibroblasts on wound healing: a histological study in a rodent model
Sousa, Ana Paula Cavalcanti de
title_short Effect of LED phototherapy of three distinct wavelengths on fibroblasts on wound healing: a histological study in a rodent model
title_full Effect of LED phototherapy of three distinct wavelengths on fibroblasts on wound healing: a histological study in a rodent model
title_fullStr Effect of LED phototherapy of three distinct wavelengths on fibroblasts on wound healing: a histological study in a rodent model
title_full_unstemmed Effect of LED phototherapy of three distinct wavelengths on fibroblasts on wound healing: a histological study in a rodent model
title_sort Effect of LED phototherapy of three distinct wavelengths on fibroblasts on wound healing: a histological study in a rodent model
author Sousa, Ana Paula Cavalcanti de
author_facet Sousa, Ana Paula Cavalcanti de
Santos, Jean Nunes dos
Reis Junior, João A. dos
Ramos, Thaís Andrade
Souza, José de
Cangussu, Maria Cristina Teixeira
Pinheiro, Antonio Luiz Barbosa
author_role author
author2 Santos, Jean Nunes dos
Reis Junior, João A. dos
Ramos, Thaís Andrade
Souza, José de
Cangussu, Maria Cristina Teixeira
Pinheiro, Antonio Luiz Barbosa
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Sousa, Ana Paula Cavalcanti de
Santos, Jean Nunes dos
Reis Junior, João A. dos
Ramos, Thaís Andrade
Souza, José de
Cangussu, Maria Cristina Teixeira
Pinheiro, Antonio Luiz Barbosa
Sousa, Ana Paula Cavalcanti de
Santos, Jean Nunes dos
Reis Junior, João A. dos
Ramos, Thaís Andrade
Souza, José de
Cangussu, Maria Cristina Teixeira
Pinheiro, Antonio Luiz Barbosa
description Texto completo: acesso restrito. p.547-552
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2013-10-31T18:20:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/13443
dc.identifier.issn.none.fl_str_mv 1549-5418
dc.identifier.number.pt_BR.fl_str_mv v. 28, n. 4
identifier_str_mv 1549-5418
v. 28, n. 4
url http://repositorio.ufba.br/ri/handle/ri/13443
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1089/pho.2009.2605
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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