Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts

Detalhes bibliográficos
Autor(a) principal: Santos, Luciano Cincurá Silva
Data de Publicação: 2007
Outros Autores: Ramos, Eduardo Antônio Gonçalves, Gurgel, Clarissa Araújo Silva, Santana, Edmar José Borges de, Santos, Jean Nunes dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15962
Resumo: Texto completo: acesso restrito. p. 201-205
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spelling Santos, Luciano Cincurá SilvaRamos, Eduardo Antônio GonçalvesGurgel, Clarissa Araújo SilvaSantana, Edmar José Borges deSantos, Jean Nunes dosSantos, Luciano Cincurá SilvaRamos, Eduardo Antônio GonçalvesGurgel, Clarissa Araújo SilvaSantana, Edmar José Borges deSantos, Jean Nunes dos2014-09-09T15:51:31Z20071567-2379http://repositorio.ufba.br/ri/handle/ri/15962v. 38, n. 3Texto completo: acesso restrito. p. 201-205Objective: Dental granulomas (DGs) and radicular cysts (RCs) are chronic periapical lesions frequently involving the jaws. Langerhans cells (LCs) are dendritic cells responsible for the presentation of antigens to T lymphocytes. This study examined the expression of LCs in DG and RCs by immunohistochemical staining. Study Design: Eighteen cases of DGs and 26 cases of RCs were analyzed using anti-CD1a marker. Results: CD1a-labeled LCs were observed in 11.1% of DGs and in 69.2% of RCs, showing a significant correlation (P < 0.0001; Fisher’s test). In DGs, LCs were only observed in granulation tissue, showing discrete immunostaining density. In RCs, LCs exhibited both a round and a dendritic shape in all epithelial layers. Although a correlation was observed between immunostaining density and epithelial thickness, as well as between immunostaining and inflammatory intensity, the differences were not significant in radicular cysts. Conclusion: Langerhans cells provide important insight into the immunopathogenesis of chronic periapical lesions.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-01-24T13:47:21Z No. of bitstreams: 1 art%3A10.1007%2Fs10735-007-9088-3.pdf: 204472 bytes, checksum: bc1085732a4c93ef84c30a0422b941c0 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-09-09T15:51:31Z (GMT) No. of bitstreams: 1 art%3A10.1007%2Fs10735-007-9088-3.pdf: 204472 bytes, checksum: bc1085732a4c93ef84c30a0422b941c0 (MD5)Made available in DSpace on 2014-09-09T15:51:31Z (GMT). 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dc.title.pt_BR.fl_str_mv Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts
dc.title.alternative.pt_BR.fl_str_mv Journal of Molecular Histology
title Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts
spellingShingle Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts
Santos, Luciano Cincurá Silva
Radicular cyst
Dental granuloma
Immunohistochemistry
Langerhans cell
title_short Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts
title_full Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts
title_fullStr Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts
title_full_unstemmed Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts
title_sort Immunohistochemical detection of Langerhans cells in dental granulomas and radicular cysts
author Santos, Luciano Cincurá Silva
author_facet Santos, Luciano Cincurá Silva
Ramos, Eduardo Antônio Gonçalves
Gurgel, Clarissa Araújo Silva
Santana, Edmar José Borges de
Santos, Jean Nunes dos
author_role author
author2 Ramos, Eduardo Antônio Gonçalves
Gurgel, Clarissa Araújo Silva
Santana, Edmar José Borges de
Santos, Jean Nunes dos
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Santos, Luciano Cincurá Silva
Ramos, Eduardo Antônio Gonçalves
Gurgel, Clarissa Araújo Silva
Santana, Edmar José Borges de
Santos, Jean Nunes dos
Santos, Luciano Cincurá Silva
Ramos, Eduardo Antônio Gonçalves
Gurgel, Clarissa Araújo Silva
Santana, Edmar José Borges de
Santos, Jean Nunes dos
dc.subject.por.fl_str_mv Radicular cyst
Dental granuloma
Immunohistochemistry
Langerhans cell
topic Radicular cyst
Dental granuloma
Immunohistochemistry
Langerhans cell
description Texto completo: acesso restrito. p. 201-205
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2014-09-09T15:51:31Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15962
dc.identifier.issn.none.fl_str_mv 1567-2379
dc.identifier.number.pt_BR.fl_str_mv v. 38, n. 3
identifier_str_mv 1567-2379
v. 38, n. 3
url http://repositorio.ufba.br/ri/handle/ri/15962
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1007/s10735-007-9088-3
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