Dereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastline

Detalhes bibliográficos
Autor(a) principal: Silva, Michelli M.
Data de Publicação: 2010
Outros Autores: Bergamasco, Juliana, Lira, Simone Possedente de, Lopes, Norberto Peporine, Hajdu, Eduardo, Peixinho, Solange, Berlinck, Roberto Gomes de Souza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/12746
Resumo: Texto completo: acesso restrito. p.886-894
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spelling Silva, Michelli M.Bergamasco, JulianaLira, Simone Possedente deLopes, Norberto PeporineHajdu, EduardoPeixinho, SolangeBerlinck, Roberto Gomes de SouzaSilva, Michelli M.Bergamasco, JulianaLira, Simone Possedente deLopes, Norberto PeporineHajdu, EduardoPeixinho, SolangeBerlinck, Roberto Gomes de Souza2013-08-27T15:13:52Z20100004-9425http://www.repositorio.ufba.br/ri/handle/ri/12746v. 63, n. 6Texto completo: acesso restrito. p.886-894In order to investigate the chemical profile of 14 specimens of Aplysina spp. marine sponges, we have developed a method based on LC-PDA-MS for the detection of bromotyrosine-derived metabolites. The method enabled the dereplication of three distinct chemotypes of bromotyrosine-derived compounds based on UV absorptions, which were further refined by electrospray ionization-mass spectrometry analysis of the brominated quasi-molecular ion clusters. This procedure led to either a single compound assignment, or a maximum of two possible isobaric compounds. The dereplication study indicated that the chemical profile of the 14 specimens of Aplysina spp. analyzed presented practically the same dibromotyrosine-derived compounds. The results obtained suggested a possible biogenetic pathway for the formation of dibromotyrosine-derived compounds of wide occurrence in Verongida sponges.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-08-27T15:13:52Z No. of bitstreams: 1 Michelli M. Silva.pdf: 524288 bytes, checksum: 163fed6b0690131158283d93abf6fa49 (MD5)Made available in DSpace on 2013-08-27T15:13:52Z (GMT). No. of bitstreams: 1 Michelli M. Silva.pdf: 524288 bytes, checksum: 163fed6b0690131158283d93abf6fa49 (MD5) Previous issue date: 2010http://dx.doi.org/10.1071/CH09616reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBADereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastlineAustralian Journal of Chemistryinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINALMichelli M. Silva.pdfMichelli M. Silva.pdfapplication/pdf524288https://repositorio.ufba.br/bitstream/ri/12746/1/Michelli%20M.%20Silva.pdf163fed6b0690131158283d93abf6fa49MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/12746/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXTMichelli M. Silva.pdf.txtMichelli M. 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dc.title.pt_BR.fl_str_mv Dereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastline
dc.title.alternative.pt_BR.fl_str_mv Australian Journal of Chemistry
title Dereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastline
spellingShingle Dereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastline
Silva, Michelli M.
title_short Dereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastline
title_full Dereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastline
title_fullStr Dereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastline
title_full_unstemmed Dereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastline
title_sort Dereplication of bromotyrosine-derived metabolites by LC-PDA-MS and analysis of the chemical profile of 14 aplysina sponge specimens from the Brazilian coastline
author Silva, Michelli M.
author_facet Silva, Michelli M.
Bergamasco, Juliana
Lira, Simone Possedente de
Lopes, Norberto Peporine
Hajdu, Eduardo
Peixinho, Solange
Berlinck, Roberto Gomes de Souza
author_role author
author2 Bergamasco, Juliana
Lira, Simone Possedente de
Lopes, Norberto Peporine
Hajdu, Eduardo
Peixinho, Solange
Berlinck, Roberto Gomes de Souza
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Michelli M.
Bergamasco, Juliana
Lira, Simone Possedente de
Lopes, Norberto Peporine
Hajdu, Eduardo
Peixinho, Solange
Berlinck, Roberto Gomes de Souza
Silva, Michelli M.
Bergamasco, Juliana
Lira, Simone Possedente de
Lopes, Norberto Peporine
Hajdu, Eduardo
Peixinho, Solange
Berlinck, Roberto Gomes de Souza
description Texto completo: acesso restrito. p.886-894
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2013-08-27T15:13:52Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/12746
dc.identifier.issn.none.fl_str_mv 0004-9425
dc.identifier.number.pt_BR.fl_str_mv v. 63, n. 6
identifier_str_mv 0004-9425
v. 63, n. 6
url http://www.repositorio.ufba.br/ri/handle/ri/12746
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1071/CH09616
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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