Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Hugo Costa
Data de Publicação: 2003
Outros Autores: Ribeiro, Tereza Cristina M., Mattos, Angela P., Valois, Sandra S., Neri, Daniela Almeida, Almeida, Patricia, Cerqueira, Celina M., Ramos, Eduardo Antônio Gonçalves, Young, Rosemary J., Vanderhoof, Jon A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/17524
Resumo: Texto completo:acesso restrito. p. 112-115 J Pediatr
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spelling Ribeiro, Hugo CostaRibeiro, Tereza Cristina M.Mattos, Angela P.Valois, Sandra S.Neri, Daniela AlmeidaAlmeida, PatriciaCerqueira, Celina M.Ramos, Eduardo Antônio GonçalvesYoung, Rosemary J.Vanderhoof, Jon A.2015-05-04T15:25:27Z20030277-2116http://repositorio.ufba.br/ri/handle/ri/17524v. 36, n. 1Texto completo:acesso restrito. p. 112-115 J PediatrBackground: Recent studies have shown that probiotics, most commonly Lactobacillus GG, may be useful in treating acute gastroenteritis. However, beneficial effects appear to be limited to a modest decrease in the duration of diarrhea. No studies have evaluated this therapy in moderate to severe dehydrating diarrhea in a metabolic facility. Methods: Male children less than 2 years of age were admitted to a metabolic unit of the Department of Pediatrics at the Federal University of Bahia, Brazil, with moderate dehydration and were randomized in a double-blind, placebo-controlled fashion. Oral rehydration solution (ORS) was administered per protocol and either placebo or Lactobacillus GG was given in combination with the ORS. Output of urine, stool, and vomitus was recorded along with stool weight, nude body weight, and standard laboratory assessments for hydration. Results: There was no significant reduction in diarrhea duration and stool output in the Lactobacillus GG group. However, Kaplan-Meier survival analysis demonstrated that, even in moderate to severe diarrhea, resolution of the illness occurred so rapidly, that statistically significant benefits of probiotic therapy could not be demonstrated. Conclusion: Our data implies that colonization must occur before benefits of probiotics can be realized. Probiotics are, therefore, likely to be of limited benefit in treating diarrheal illnesses of short duration such as viral enteritis. The beneficial effects of probiotics may be limited to prophylactic usage in high-risk populations. JPGN 36:112–115, 2003. © 2003 Lippincott Williams & Wilkins, Inc.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-01-24T15:37:45Z No. of bitstreams: 1 Hugo Costa Ribeiro.pdf: 211753 bytes, checksum: 20d5de226ac990e0078dfe1034431b9b (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2015-05-04T15:25:27Z (GMT) No. of bitstreams: 1 Hugo Costa Ribeiro.pdf: 211753 bytes, checksum: 20d5de226ac990e0078dfe1034431b9b (MD5)Made available in DSpace on 2015-05-04T15:25:27Z (GMT). No. of bitstreams: 1 Hugo Costa Ribeiro.pdf: 211753 bytes, checksum: 20d5de226ac990e0078dfe1034431b9b (MD5) Previous issue date: 2003PediatricsDiarrheaFluid TherapyLimitations of Probiotic Therapy in Acute, Severe Dehydrating DiarrheaJournal of Pediatric Gastroenterology and Nutritioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01Brasilinfo:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBALICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/17524/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52ORIGINALHugo Costa Ribeiro.pdfHugo Costa Ribeiro.pdfapplication/pdf211753https://repositorio.ufba.br/bitstream/ri/17524/1/Hugo%20Costa%20Ribeiro.pdf20d5de226ac990e0078dfe1034431b9bMD51TEXTHugo Costa Ribeiro.pdf.txtHugo Costa Ribeiro.pdf.txtExtracted texttext/plain19925https://repositorio.ufba.br/bitstream/ri/17524/3/Hugo%20Costa%20Ribeiro.pdf.txt66af180b45b077cc29801b622f984308MD53ri/175242022-03-10 14:02:13.047oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-03-10T17:02:13Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea
dc.title.alternative.pt_BR.fl_str_mv Journal of Pediatric Gastroenterology and Nutrition
title Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea
spellingShingle Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea
Ribeiro, Hugo Costa
Pediatrics
Diarrhea
Fluid Therapy
title_short Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea
title_full Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea
title_fullStr Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea
title_full_unstemmed Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea
title_sort Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea
author Ribeiro, Hugo Costa
author_facet Ribeiro, Hugo Costa
Ribeiro, Tereza Cristina M.
Mattos, Angela P.
Valois, Sandra S.
Neri, Daniela Almeida
Almeida, Patricia
Cerqueira, Celina M.
Ramos, Eduardo Antônio Gonçalves
Young, Rosemary J.
Vanderhoof, Jon A.
author_role author
author2 Ribeiro, Tereza Cristina M.
Mattos, Angela P.
Valois, Sandra S.
Neri, Daniela Almeida
Almeida, Patricia
Cerqueira, Celina M.
Ramos, Eduardo Antônio Gonçalves
Young, Rosemary J.
Vanderhoof, Jon A.
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Ribeiro, Hugo Costa
Ribeiro, Tereza Cristina M.
Mattos, Angela P.
Valois, Sandra S.
Neri, Daniela Almeida
Almeida, Patricia
Cerqueira, Celina M.
Ramos, Eduardo Antônio Gonçalves
Young, Rosemary J.
Vanderhoof, Jon A.
dc.subject.por.fl_str_mv Pediatrics
Diarrhea
Fluid Therapy
topic Pediatrics
Diarrhea
Fluid Therapy
description Texto completo:acesso restrito. p. 112-115 J Pediatr
publishDate 2003
dc.date.issued.fl_str_mv 2003
dc.date.accessioned.fl_str_mv 2015-05-04T15:25:27Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/17524
dc.identifier.issn.none.fl_str_mv 0277-2116
dc.identifier.number.pt_BR.fl_str_mv v. 36, n. 1
identifier_str_mv 0277-2116
v. 36, n. 1
url http://repositorio.ufba.br/ri/handle/ri/17524
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.country.fl_str_mv Brasil
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