Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer

Detalhes bibliográficos
Autor(a) principal: Machado, Paulo Roberto Lima
Data de Publicação: 2002
Outros Autores: Araújo, Cibele, Silva, Andréa T. da, Almeida, Roque Pacheco de, D'Oliveira Junior, Argemiro, Bittencourt, Achilea Candida Lisboa, Carvalho Filho, Edgar Marcelino de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/16641
Resumo: Texto completo: acesso restrito. p. 69-73
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spelling Machado, Paulo Roberto LimaAraújo, CibeleSilva, Andréa T. daAlmeida, Roque Pacheco deD'Oliveira Junior, ArgemiroBittencourt, Achilea Candida LisboaCarvalho Filho, Edgar Marcelino deMachado, Paulo Roberto LimaAraújo, CibeleSilva, Andréa T. daAlmeida, Roque Pacheco deD'Oliveira Junior, ArgemiroBittencourt, Achilea Candida LisboaCarvalho Filho, Edgar Marcelino de2014-11-21T13:50:43Z20021058-4838http://repositorio.ufba.br/ri/handle/ri/16641v. 34, n. 12Texto completo: acesso restrito. p. 69-73The clinical characteristics and treatment outcome were determined for 26 patients who presented with early-stage cutaneous leishmaniasis. Illness duration ranged from 8 to 20 days, and the commonest clinical presentation was the presence of a papule with small central crust on a lower extremity. Prominent regional adenopathy was found in 22 (85%) of 26 patients. The results of an intradermal skin test for Leishmania were positive for 96% of those patients, and results of serologic testing were positive for 61% of patients tested. Ten (46%) of 22 patients for whom follow-up data were available developed enlargement and ulceration of the lesion despite early antimony therapy and required additional courses of treatment. Histopathological studies of samples from the lesions of 3 patients showed vasculitis. These data show that early therapy for cutaneous leishmaniasis does not prevent the development of an ulcer in one-half of patients. This unfavorable outcome underlines the relevance of local exacerbated inflammatory and immune response in the pathogenesis of the disease.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-01-20T12:55:22Z No. of bitstreams: 1 Paulo Machado.pdf: 283941 bytes, checksum: 8a820425f50c84a4911718fdbc9636f6 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-11-21T13:50:43Z (GMT) No. of bitstreams: 1 Paulo Machado.pdf: 283941 bytes, checksum: 8a820425f50c84a4911718fdbc9636f6 (MD5)Made available in DSpace on 2014-11-21T13:50:43Z (GMT). No. of bitstreams: 1 Paulo Machado.pdf: 283941 bytes, checksum: 8a820425f50c84a4911718fdbc9636f6 (MD5) Previous issue date: 2002http://dx.doi.org/ 10.1086/340526reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBALeishmaniasis, CutaneousUlcerFailure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcerClinical Infectious Diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengLICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16641/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52ORIGINALPaulo Machado.pdfPaulo Machado.pdfapplication/pdf283941https://repositorio.ufba.br/bitstream/ri/16641/1/Paulo%20Machado.pdf8a820425f50c84a4911718fdbc9636f6MD51TEXTPaulo Machado.pdf.txtPaulo Machado.pdf.txtExtracted texttext/plain20655https://repositorio.ufba.br/bitstream/ri/16641/3/Paulo%20Machado.pdf.txt03b1ba0bb0aaeeb2ba28549d58649a8eMD53ri/166412022-07-05 14:03:44.014oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:44Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer
dc.title.alternative.pt_BR.fl_str_mv Clinical Infectious Diseases
title Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer
spellingShingle Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer
Machado, Paulo Roberto Lima
Leishmaniasis, Cutaneous
Ulcer
title_short Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer
title_full Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer
title_fullStr Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer
title_full_unstemmed Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer
title_sort Failure of early treatment of Cutaneous Leishmaniasis in preventing the development of an ulcer
author Machado, Paulo Roberto Lima
author_facet Machado, Paulo Roberto Lima
Araújo, Cibele
Silva, Andréa T. da
Almeida, Roque Pacheco de
D'Oliveira Junior, Argemiro
Bittencourt, Achilea Candida Lisboa
Carvalho Filho, Edgar Marcelino de
author_role author
author2 Araújo, Cibele
Silva, Andréa T. da
Almeida, Roque Pacheco de
D'Oliveira Junior, Argemiro
Bittencourt, Achilea Candida Lisboa
Carvalho Filho, Edgar Marcelino de
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Machado, Paulo Roberto Lima
Araújo, Cibele
Silva, Andréa T. da
Almeida, Roque Pacheco de
D'Oliveira Junior, Argemiro
Bittencourt, Achilea Candida Lisboa
Carvalho Filho, Edgar Marcelino de
Machado, Paulo Roberto Lima
Araújo, Cibele
Silva, Andréa T. da
Almeida, Roque Pacheco de
D'Oliveira Junior, Argemiro
Bittencourt, Achilea Candida Lisboa
Carvalho Filho, Edgar Marcelino de
dc.subject.por.fl_str_mv Leishmaniasis, Cutaneous
Ulcer
topic Leishmaniasis, Cutaneous
Ulcer
description Texto completo: acesso restrito. p. 69-73
publishDate 2002
dc.date.issued.fl_str_mv 2002
dc.date.accessioned.fl_str_mv 2014-11-21T13:50:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/16641
dc.identifier.issn.none.fl_str_mv 1058-4838
dc.identifier.number.pt_BR.fl_str_mv v. 34, n. 12
identifier_str_mv 1058-4838
v. 34, n. 12
url http://repositorio.ufba.br/ri/handle/ri/16641
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.pt_BR.fl_str_mv http://dx.doi.org/ 10.1086/340526
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