Angiogenesis and osteogenesis at incorporation process of onlay bone graft

Detalhes bibliográficos
Autor(a) principal: Moreira, David Costa
Data de Publicação: 2013
Outros Autores: Sá, Camila Neves, Andrade, Miguel Gustavo Setúbal, Bittencourt, Thereza Cristina Borio dos Santos Calmon de, Reis, Silvia Regina de Almeida, Pithon, Matheus Melo, Sadigursky, Moysés
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15918
Resumo: Texto completo: acesso restrito. p. 2048–2057
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spelling Moreira, David CostaSá, Camila NevesAndrade, Miguel Gustavo SetúbalBittencourt, Thereza Cristina Borio dos Santos Calmon deReis, Silvia Regina de AlmeidaPithon, Matheus MeloSadigursky, MoysésMoreira, David CostaSá, Camila NevesAndrade, Miguel Gustavo SetúbalBittencourt, Thereza Cristina Borio dos Santos Calmon deReis, Silvia Regina de AlmeidaPithon, Matheus MeloSadigursky, Moysés2014-09-09T15:12:14Z20130278-2391http://repositorio.ufba.br/ri/handle/ri/15918v. 71, n. 12Texto completo: acesso restrito. p. 2048–2057Purpose: The roles of angiogenesis and osteogenesis in autologous and allogenic bone grafts and the use of platelet-rich plasma (PRP) as a modifier were investigated. Materials and Methods: Forty rabbit mandibles received onlay grafts of fresh autologous and frozen allogeneic bone. PRP was added on the right side. After intervals of 3, 7, 14, 28, and 56 days, the animals were euthanized. Hematoxylin and eosin staining was used to measure the quantity and area of osteoblasts. Sections stained with toluidine blue showed newly formed bone area. In sections with Weigert-van Gieson staining, the number of vessels and their lumens was quantified. The quantity and area of cellular arrangements expressing CD31 and the area of vessels were obtained. Results: Quantities of osteoblasts and their areas, newly formed matrices, and vessels and their lumen areas were obtained and identified by immunomarking with CD31. In general, values for these were higher in rabbits with allogeneic bone grafts and on the sides where PRP had been added. There was a variable significance between categories and days. It was confirmed that osteogenesis was intensified when angiogenesis was consolidated. Conclusions: Angiogenesis was important for greater osteoblast differentiation and bone matrix synthesis, ensuring consolidation of onlay grafts with the receptor bed. Allogeneic grafts and PRP intensified these processes.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-04-01T12:03:18Z No. of bitstreams: 1 1-s2.0-S0278239113008215-main.pdf: 1539074 bytes, checksum: 19ccd162cd451e8fa7a4b5f03c367538 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-09-09T15:12:14Z (GMT) No. of bitstreams: 1 1-s2.0-S0278239113008215-main.pdf: 1539074 bytes, checksum: 19ccd162cd451e8fa7a4b5f03c367538 (MD5)Made available in DSpace on 2014-09-09T15:12:14Z (GMT). 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dc.title.pt_BR.fl_str_mv Angiogenesis and osteogenesis at incorporation process of onlay bone graft
dc.title.alternative.pt_BR.fl_str_mv Journal of Oral and Maxillofacial Surgery
title Angiogenesis and osteogenesis at incorporation process of onlay bone graft
spellingShingle Angiogenesis and osteogenesis at incorporation process of onlay bone graft
Moreira, David Costa
title_short Angiogenesis and osteogenesis at incorporation process of onlay bone graft
title_full Angiogenesis and osteogenesis at incorporation process of onlay bone graft
title_fullStr Angiogenesis and osteogenesis at incorporation process of onlay bone graft
title_full_unstemmed Angiogenesis and osteogenesis at incorporation process of onlay bone graft
title_sort Angiogenesis and osteogenesis at incorporation process of onlay bone graft
author Moreira, David Costa
author_facet Moreira, David Costa
Sá, Camila Neves
Andrade, Miguel Gustavo Setúbal
Bittencourt, Thereza Cristina Borio dos Santos Calmon de
Reis, Silvia Regina de Almeida
Pithon, Matheus Melo
Sadigursky, Moysés
author_role author
author2 Sá, Camila Neves
Andrade, Miguel Gustavo Setúbal
Bittencourt, Thereza Cristina Borio dos Santos Calmon de
Reis, Silvia Regina de Almeida
Pithon, Matheus Melo
Sadigursky, Moysés
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Moreira, David Costa
Sá, Camila Neves
Andrade, Miguel Gustavo Setúbal
Bittencourt, Thereza Cristina Borio dos Santos Calmon de
Reis, Silvia Regina de Almeida
Pithon, Matheus Melo
Sadigursky, Moysés
Moreira, David Costa
Sá, Camila Neves
Andrade, Miguel Gustavo Setúbal
Bittencourt, Thereza Cristina Borio dos Santos Calmon de
Reis, Silvia Regina de Almeida
Pithon, Matheus Melo
Sadigursky, Moysés
description Texto completo: acesso restrito. p. 2048–2057
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2014-09-09T15:12:14Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15918
dc.identifier.issn.none.fl_str_mv 0278-2391
dc.identifier.number.pt_BR.fl_str_mv v. 71, n. 12
identifier_str_mv 0278-2391
v. 71, n. 12
url http://repositorio.ufba.br/ri/handle/ri/15918
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