Hereditary angioedema: quality of life in Brazilian patients
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2013 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/17654 |
Resumo: | p.81-83 |
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Gomide, Maria Abadia Consuelo M. S.Toledo, ElianaValle, Solange Oliveira RodriguesCampos, Régis de AlbuquerqueFrança, Alfeu T.Gomez, Nieves PriorAndrade Junior, Heitor FrancoCaballero, TeresaGrumach, Anete S.Gomide, Maria Abadia Consuelo M. S.Toledo, ElianaValle, Solange Oliveira RodriguesCampos, Régis de AlbuquerqueFrança, Alfeu T.Gomez, Nieves PriorAndrade Junior, Heitor FrancoCaballero, TeresaGrumach, Anete S.2015-05-11T14:47:38Z2015-05-11T14:47:38Z20131807-5932http://repositorio.ufba.br/ri/handle/ri/17654v. 68, n. 1p.81-83OBJECTIVE: Hereditary angioedema is a serious medical condition caused by a rare autosomal dominant genetic disorder and it is associated with deficient production or dysfunction of the C1 esterase inhibitor. In most cases, affected patients experience unexpected and recurrent crises of subcutaneous, gastrointestinal and laryngeal edema. The unpredictability, intensity and other factors associated with the disease impact the quality of life of hereditary angioedema patients. We evaluated the quality of life in Brazilian hereditary angioedema patients. METHODS Patients older than 15 years with any severity of hereditary angioedema and laboratory confirmation of C1 inhibitor deficiency were included. Two questionnaires were used: a clinical questionnaire and the SF-36 (a generic questionnaire). This protocol was approved by the Ethics Committee of Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. RESULTS: The SF-36 showed that 90.4% (mean) of all the patients had a score below 70 and 9.6% had scores equal to or higher than 70. The scores of the eight dimensions ranged from 51.03 to 75.95; vitality and social aspects were more affected than other arenas. The internal consistency of the evaluation was demonstrated by a Cronbach's alpha value above 0.7 in seven of the eight domains. CONCLUSIONS: In this study, Brazilian patients demonstrated an impaired quality of life, as measured by the SF-36. The most affected domains were those related to vitality and social characteristics. The generic SF-36 questionnaire was relevant to the evaluation of quality of life; however, there is a need for more specific instruments for better evaluation.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2015-03-10T15:02:45Z No. of bitstreams: 1 Maria Abadia Consuelo M S Gomide.pdf: 197451 bytes, checksum: 4b7b6bf6c881a971f9f2174b3b32b9ca (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2015-05-11T14:47:38Z (GMT) No. of bitstreams: 1 Maria Abadia Consuelo M S Gomide.pdf: 197451 bytes, checksum: 4b7b6bf6c881a971f9f2174b3b32b9ca (MD5)Made available in DSpace on 2015-05-11T14:47:38Z (GMT). No. of bitstreams: 1 Maria Abadia Consuelo M S Gomide.pdf: 197451 bytes, checksum: 4b7b6bf6c881a971f9f2174b3b32b9ca (MD5) Previous issue date: 2013http://dx.doi.org/ 10.6061/clinics/2013(01)OA13reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAHereditary angioedemaQuality of lifeQuestionnairesSF-36AsphyxiaHereditary angioedema: quality of life in Brazilian patientsClinicsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBrasilinfo:eu-repo/semantics/openAccessengORIGINALMaria Abadia Consuelo M S Gomide.pdfMaria Abadia Consuelo M S Gomide.pdfapplication/pdf197451https://repositorio.ufba.br/bitstream/ri/17654/1/Maria%20Abadia%20Consuelo%20M%20S%20Gomide.pdf4b7b6bf6c881a971f9f2174b3b32b9caMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/17654/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTMaria Abadia Consuelo M S Gomide.pdf.txtMaria Abadia Consuelo M S Gomide.pdf.txtExtracted texttext/plain16025https://repositorio.ufba.br/bitstream/ri/17654/3/Maria%20Abadia%20Consuelo%20M%20S%20Gomide.pdf.txtb1a7810b7ec229a5dd6593f249f5d88dMD53ri/176542022-07-05 14:05:18.268oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:05:18Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Hereditary angioedema: quality of life in Brazilian patients |
| dc.title.alternative.pt_BR.fl_str_mv |
Clinics |
| title |
Hereditary angioedema: quality of life in Brazilian patients |
| spellingShingle |
Hereditary angioedema: quality of life in Brazilian patients Gomide, Maria Abadia Consuelo M. S. Hereditary angioedema Quality of life Questionnaires SF-36 Asphyxia |
| title_short |
Hereditary angioedema: quality of life in Brazilian patients |
| title_full |
Hereditary angioedema: quality of life in Brazilian patients |
| title_fullStr |
Hereditary angioedema: quality of life in Brazilian patients |
| title_full_unstemmed |
Hereditary angioedema: quality of life in Brazilian patients |
| title_sort |
Hereditary angioedema: quality of life in Brazilian patients |
| author |
Gomide, Maria Abadia Consuelo M. S. |
| author_facet |
Gomide, Maria Abadia Consuelo M. S. Toledo, Eliana Valle, Solange Oliveira Rodrigues Campos, Régis de Albuquerque França, Alfeu T. Gomez, Nieves Prior Andrade Junior, Heitor Franco Caballero, Teresa Grumach, Anete S. |
| author_role |
author |
| author2 |
Toledo, Eliana Valle, Solange Oliveira Rodrigues Campos, Régis de Albuquerque França, Alfeu T. Gomez, Nieves Prior Andrade Junior, Heitor Franco Caballero, Teresa Grumach, Anete S. |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Gomide, Maria Abadia Consuelo M. S. Toledo, Eliana Valle, Solange Oliveira Rodrigues Campos, Régis de Albuquerque França, Alfeu T. Gomez, Nieves Prior Andrade Junior, Heitor Franco Caballero, Teresa Grumach, Anete S. Gomide, Maria Abadia Consuelo M. S. Toledo, Eliana Valle, Solange Oliveira Rodrigues Campos, Régis de Albuquerque França, Alfeu T. Gomez, Nieves Prior Andrade Junior, Heitor Franco Caballero, Teresa Grumach, Anete S. |
| dc.subject.por.fl_str_mv |
Hereditary angioedema Quality of life Questionnaires SF-36 Asphyxia |
| topic |
Hereditary angioedema Quality of life Questionnaires SF-36 Asphyxia |
| description |
p.81-83 |
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2013 |
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2013 |
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2015-05-11T14:47:38Z |
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2015-05-11T14:47:38Z |
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1807-5932 |
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v. 68, n. 1 |
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1807-5932 v. 68, n. 1 |
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