Haemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensis

Detalhes bibliográficos
Autor(a) principal: Guedes, M. T. B.
Data de Publicação: 2012
Outros Autores: Santos, S. C. O., López, J. A., Meira, M., David, Jorge Mauricio, Zacharias, Farouk, David, Juceni Pereira de Lima, Lima, F. W. M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15510
Resumo: Texto completo: acesso restrito. p. 492–493
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spelling Guedes, M. T. B.Santos, S. C. O.López, J. A.Meira, M.David, Jorge MauricioZacharias, FaroukDavid, Juceni Pereira de LimaLima, F. W. M.Guedes, M. T. B.Santos, S. C. O.López, J. A.Meira, M.David, Jorge MauricioZacharias, FaroukDavid, Juceni Pereira de LimaLima, F. W. M.2014-08-07T17:42:32Z20120034-5288http://repositorio.ufba.br/ri/handle/ri/15510v. 92, n. 3Texto completo: acesso restrito. p. 492–493This report describes the inhibition of the proteolytic activity of Haemonchus contortus lysate by a mixture of n-alkyl ferulates isolated from Maprounea guianensis. These compounds were evaluated in vitro for the ability to inhibit the H. contortus proteases using SDS–PAGE copolymerized with gelatine (zymography) and by assaying the hemoglobinolytic activity of these enzymes in solution. The ferulates abrogated the proteolysis compared to E-64, suggesting the activity is the result of a cysteine protease.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-06T13:36:08Z No. of bitstreams: 1 M. T. B. Guedes.pdf: 199192 bytes, checksum: 7c5356840d291ce2a9f5b13c34e31cb7 (MD5)Approved for entry into archive by Patricia Barroso (pbarroso@ufba.br) on 2014-08-07T17:42:32Z (GMT) No. of bitstreams: 1 M. T. B. Guedes.pdf: 199192 bytes, checksum: 7c5356840d291ce2a9f5b13c34e31cb7 (MD5)Made available in DSpace on 2014-08-07T17:42:32Z (GMT). No. of bitstreams: 1 M. T. B. Guedes.pdf: 199192 bytes, checksum: 7c5356840d291ce2a9f5b13c34e31cb7 (MD5) Previous issue date: 2012http://dx.doi.org/ 10.1016/j.rvsc.2011.06.001reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAHaemonchus contortusProtease inhibitionN-Alkyl ferulatesHaemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensisResearch in Veterinary Scienceinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALM. T. B. Guedes.pdfM. T. B. Guedes.pdfapplication/pdf199192https://repositorio.ufba.br/bitstream/ri/15510/1/M.%20T.%20B.%20Guedes.pdf7c5356840d291ce2a9f5b13c34e31cb7MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/15510/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTM. T. B. Guedes.pdf.txtM. T. B. Guedes.pdf.txtExtracted texttext/plain8489https://repositorio.ufba.br/bitstream/ri/15510/3/M.%20T.%20B.%20Guedes.pdf.txt43d11879e0f23a78f0d9080c71bf2cc6MD53ri/155102022-07-05 14:03:14.569oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:14Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Haemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensis
dc.title.alternative.pt_BR.fl_str_mv Research in Veterinary Science
title Haemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensis
spellingShingle Haemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensis
Guedes, M. T. B.
Haemonchus contortus
Protease inhibition
N-Alkyl ferulates
title_short Haemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensis
title_full Haemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensis
title_fullStr Haemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensis
title_full_unstemmed Haemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensis
title_sort Haemonchus contortus protease inhibition by n-alkyl ferulates from Maprounea guianensis
author Guedes, M. T. B.
author_facet Guedes, M. T. B.
Santos, S. C. O.
López, J. A.
Meira, M.
David, Jorge Mauricio
Zacharias, Farouk
David, Juceni Pereira de Lima
Lima, F. W. M.
author_role author
author2 Santos, S. C. O.
López, J. A.
Meira, M.
David, Jorge Mauricio
Zacharias, Farouk
David, Juceni Pereira de Lima
Lima, F. W. M.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Guedes, M. T. B.
Santos, S. C. O.
López, J. A.
Meira, M.
David, Jorge Mauricio
Zacharias, Farouk
David, Juceni Pereira de Lima
Lima, F. W. M.
Guedes, M. T. B.
Santos, S. C. O.
López, J. A.
Meira, M.
David, Jorge Mauricio
Zacharias, Farouk
David, Juceni Pereira de Lima
Lima, F. W. M.
dc.subject.por.fl_str_mv Haemonchus contortus
Protease inhibition
N-Alkyl ferulates
topic Haemonchus contortus
Protease inhibition
N-Alkyl ferulates
description Texto completo: acesso restrito. p. 492–493
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2014-08-07T17:42:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15510
dc.identifier.issn.none.fl_str_mv 0034-5288
dc.identifier.number.pt_BR.fl_str_mv v. 92, n. 3
identifier_str_mv 0034-5288
v. 92, n. 3
url http://repositorio.ufba.br/ri/handle/ri/15510
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.pt_BR.fl_str_mv http://dx.doi.org/ 10.1016/j.rvsc.2011.06.001
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