Ovarian function after seven years' use of a levonorgestrel IUD

Detalhes bibliográficos
Autor(a) principal: Barbosa, Ione Cristina
Data de Publicação: 1995
Outros Autores: Olsson, S. E., Odlind, V., Goncalves, T., Coutinho, E.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/13743
Resumo: Texto completo. Acesso restrito. p. 85-95
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spelling Barbosa, Ione CristinaOlsson, S. E.Odlind, V.Goncalves, T.Coutinho, E.Barbosa, Ione CristinaOlsson, S. E.Odlind, V.Goncalves, T.Coutinho, E.2013-11-19T19:51:24Z19950267-4874http://repositorio.ufba.br/ri/handle/ri/13743Texto completo. Acesso restrito. p. 85-95Fifteen women with regular menstrual periods and seven amenorrheic women who had been using a levonorgestrel-releasing (LNg) IUD for more than seven years were studied. For controls, eight women using TCu380Ag IUDs for more than seven years were studied during two complete menstrual cycles. Ovarian function was assessed with hormonal determination and ultrasound examinations. The regularly menstruating women were studied for two complete menstrual cycles and the amenorrheic women for eight weeks. In the regularly menstruating LNg-IUD users, according to progesterone levels, 93% of the cycles were ovulatory but just 58% of these 'ovulatory' cycles showed normal follicular growth and rupture. Follicular cysts and luteinization of regressing follicles were observed in 42% of the 26 'ovulatory' cycles studied. SHBG capacity was decreased in the LNg-IUD users compared with the TCu380Ag users. Progesterone levels were lower in the LNg-IUD users compared with the TCu380Ag users but this difference was not statistically significant. Preovulatory estradiol and LH levels were lower in the LNg-IUD users than in the TCu380Ag users. These differences were not statistically significant. For the amenorrheic women, five had follicular cysts that disappeared spontaneously within 45 days. Two women showed follicular development and rupture. The presence of good cervical mucus was observed in 69% of the ovulatory cycles studied in the LNg-IUD users. This indicates that effects on cervical mucus cannot be the main mechanism of action of the LNg-IUDs. It is concluded that LNg-IUDs may exert a contraceptive effect in many different ways, such as inhibition of ovulation, endometrial changes preventing implantation, alteration of physical and chemical properties of cervical mucus affecting sperm transport and subtle disturbances in hypothalamic pituitary ovarian function, resulting in alterations of follicular development and rupture.Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-09-12T19:43:50Z No. of bitstreams: 1 2222222222222222222.pdf: 940899 bytes, checksum: b8f69cd848d2007b34431e009b6f5de5 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-19T19:51:24Z (GMT) No. of bitstreams: 1 2222222222222222222.pdf: 940899 bytes, checksum: b8f69cd848d2007b34431e009b6f5de5 (MD5)Made available in DSpace on 2013-11-19T19:51:24Z (GMT). No. of bitstreams: 1 2222222222222222222.pdf: 940899 bytes, checksum: b8f69cd848d2007b34431e009b6f5de5 (MD5) Previous issue date: 1995SalvadorAdvances in Contraceptionhttp://link-springer-com.ez10.periodicos.capes.gov.br/content/pdf/10.1007%2FBF01987274.pdfreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAOvarian function after seven years' use of a levonorgestrel IUDAdvances in Contraceptioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL2222222222222222222.pdf2222222222222222222.pdfapplication/pdf940899https://repositorio.ufba.br/bitstream/ri/13743/1/2222222222222222222.pdfb8f69cd848d2007b34431e009b6f5de5MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/13743/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT2222222222222222222.pdf.txt2222222222222222222.pdf.txtExtracted texttext/plain27722https://repositorio.ufba.br/bitstream/ri/13743/3/2222222222222222222.pdf.txt6473d20bb55376431a4e3072ba73dafdMD53ri/137432022-08-08 13:17:35.447oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:35Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Ovarian function after seven years' use of a levonorgestrel IUD
dc.title.alternative.pt_BR.fl_str_mv Advances in Contraception
title Ovarian function after seven years' use of a levonorgestrel IUD
spellingShingle Ovarian function after seven years' use of a levonorgestrel IUD
Barbosa, Ione Cristina
title_short Ovarian function after seven years' use of a levonorgestrel IUD
title_full Ovarian function after seven years' use of a levonorgestrel IUD
title_fullStr Ovarian function after seven years' use of a levonorgestrel IUD
title_full_unstemmed Ovarian function after seven years' use of a levonorgestrel IUD
title_sort Ovarian function after seven years' use of a levonorgestrel IUD
author Barbosa, Ione Cristina
author_facet Barbosa, Ione Cristina
Olsson, S. E.
Odlind, V.
Goncalves, T.
Coutinho, E.
author_role author
author2 Olsson, S. E.
Odlind, V.
Goncalves, T.
Coutinho, E.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Barbosa, Ione Cristina
Olsson, S. E.
Odlind, V.
Goncalves, T.
Coutinho, E.
Barbosa, Ione Cristina
Olsson, S. E.
Odlind, V.
Goncalves, T.
Coutinho, E.
description Texto completo. Acesso restrito. p. 85-95
publishDate 1995
dc.date.issued.fl_str_mv 1995
dc.date.accessioned.fl_str_mv 2013-11-19T19:51:24Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/13743
dc.identifier.issn.none.fl_str_mv 0267-4874
identifier_str_mv 0267-4874
url http://repositorio.ufba.br/ri/handle/ri/13743
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Advances in Contraception
publisher.none.fl_str_mv Advances in Contraception
dc.source.pt_BR.fl_str_mv http://link-springer-com.ez10.periodicos.capes.gov.br/content/pdf/10.1007%2FBF01987274.pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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instname_str Universidade Federal da Bahia (UFBA)
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reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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