Morphological alterations in the kidney of rats with natural and experimental leptospira infection

Bibliographic Details
Main Author: Faria, M. Tucunduva de
Publication Date: 2007
Other Authors: Athanazio, Daniel Abensur, Ramos, Eduardo Antônio Gonçalves, Silva, E. F., Reis, M. G., Ko, A. I.
Format: Article
Language: eng
Source: Repositório Institucional da UFBA
Download full: http://repositorio.ufba.br/ri/handle/ri/15973
Summary: Texto completo: acesso restrito. p. 231-238
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spelling Faria, M. Tucunduva deAthanazio, Daniel AbensurRamos, Eduardo Antônio GonçalvesSilva, E. F.Reis, M. G.Ko, A. I.Faria, M. Tucunduva deAthanazio, Daniel AbensurRamos, Eduardo Antônio GonçalvesSilva, E. F.Reis, M. G.Ko, A. I.2014-09-09T15:56:00Z20070021-9975http://repositorio.ufba.br/ri/handle/ri/15973v. 137, n. 4Texto completo: acesso restrito. p. 231-238Leptospirosis is a widespread anthropozoonosis, with a broad array of mammalian reservoirs, occurring as rural endemics, urban outbreaks related to floods, and emergent disease associated with water sports and recreational exposure in developed countries. Rats are the major source of human infection, particularly in urban areas; however few reports have focused on the pathology of leptospirosis in this host. This study reports pathological changes in 60 kidneys from captured wild rats and compares these with changes in the kidney of Wistar rats experimentally infected with Leptospira interrogans serovar Copenhageni strain FIOCRUZ L1-130. A broad range of morphological alterations were detected in the kidneys from captured rats but interstitial nephritis was the only feature reproduced under experimental conditions. The role of interstitial nephritis in the pathogenesis of leptospirosis is reviewed and it is suggested that rats may provide a potential tool for the study of colonization mechanisms and host resistance in acute leptospiral disease.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-01-07T16:30:38Z No. of bitstreams: 1 1-s2.0-S0021997507001338-main.pdf: 1419911 bytes, checksum: 782e1299445c48fa0874714687c6f544 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-09-09T15:55:59Z (GMT) No. of bitstreams: 1 1-s2.0-S0021997507001338-main.pdf: 1419911 bytes, checksum: 782e1299445c48fa0874714687c6f544 (MD5)Made available in DSpace on 2014-09-09T15:56:00Z (GMT). No. of bitstreams: 1 1-s2.0-S0021997507001338-main.pdf: 1419911 bytes, checksum: 782e1299445c48fa0874714687c6f544 (MD5) Previous issue date: 2007http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.jcpa.2007.08.001reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBALeptospirosisRattus norvegicusInterstitial nephritisKidneyMorphological alterations in the kidney of rats with natural and experimental leptospira infectionJournal of Comparative Pathologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL1-s2.0-S0021997507001338-main.pdf1-s2.0-S0021997507001338-main.pdfapplication/pdf1419911https://repositorio.ufba.br/bitstream/ri/15973/1/1-s2.0-S0021997507001338-main.pdf782e1299445c48fa0874714687c6f544MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/15973/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXT1-s2.0-S0021997507001338-main.pdf.txt1-s2.0-S0021997507001338-main.pdf.txtExtracted texttext/plain29817https://repositorio.ufba.br/bitstream/ri/15973/3/1-s2.0-S0021997507001338-main.pdf.txt57a02563e97f0bb9f21fb92b943009d8MD53ri/159732022-08-08 13:17:54.332oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:54Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Morphological alterations in the kidney of rats with natural and experimental leptospira infection
dc.title.alternative.pt_BR.fl_str_mv Journal of Comparative Pathology
title Morphological alterations in the kidney of rats with natural and experimental leptospira infection
spellingShingle Morphological alterations in the kidney of rats with natural and experimental leptospira infection
Faria, M. Tucunduva de
Leptospirosis
Rattus norvegicus
Interstitial nephritis
Kidney
title_short Morphological alterations in the kidney of rats with natural and experimental leptospira infection
title_full Morphological alterations in the kidney of rats with natural and experimental leptospira infection
title_fullStr Morphological alterations in the kidney of rats with natural and experimental leptospira infection
title_full_unstemmed Morphological alterations in the kidney of rats with natural and experimental leptospira infection
title_sort Morphological alterations in the kidney of rats with natural and experimental leptospira infection
author Faria, M. Tucunduva de
author_facet Faria, M. Tucunduva de
Athanazio, Daniel Abensur
Ramos, Eduardo Antônio Gonçalves
Silva, E. F.
Reis, M. G.
Ko, A. I.
author_role author
author2 Athanazio, Daniel Abensur
Ramos, Eduardo Antônio Gonçalves
Silva, E. F.
Reis, M. G.
Ko, A. I.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Faria, M. Tucunduva de
Athanazio, Daniel Abensur
Ramos, Eduardo Antônio Gonçalves
Silva, E. F.
Reis, M. G.
Ko, A. I.
Faria, M. Tucunduva de
Athanazio, Daniel Abensur
Ramos, Eduardo Antônio Gonçalves
Silva, E. F.
Reis, M. G.
Ko, A. I.
dc.subject.por.fl_str_mv Leptospirosis
Rattus norvegicus
Interstitial nephritis
Kidney
topic Leptospirosis
Rattus norvegicus
Interstitial nephritis
Kidney
description Texto completo: acesso restrito. p. 231-238
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2014-09-09T15:56:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15973
dc.identifier.issn.none.fl_str_mv 0021-9975
dc.identifier.number.pt_BR.fl_str_mv v. 137, n. 4
identifier_str_mv 0021-9975
v. 137, n. 4
url http://repositorio.ufba.br/ri/handle/ri/15973
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.jcpa.2007.08.001
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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