Risk factors associated with asymptomatic infection by Leishmania chagasi in north-east Brazil

Bibliographic Details
Main Author: Caldas, A. J. M.
Publication Date: 2002
Other Authors: Costa, J. M. L., Silva, A. A. M., Vinhas, Vera Silvia de Freitas, Barral, Aldina Maria Prado
Format: Article
Language: eng
Source: Repositório Institucional da UFBA
Download full: http://www.repositorio.ufba.br/ri/handle/ri/7603
Summary: Texto completo: acesso restrito. p. 21–28
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spelling Caldas, A. J. M.Costa, J. M. L.Silva, A. A. M.Vinhas, Vera Silvia de FreitasBarral, Aldina Maria PradoCaldas, A. J. M.Costa, J. M. L.Silva, A. A. M.Vinhas, Vera Silvia de FreitasBarral, Aldina Maria Prado2012-12-17T16:27:15Z20020035-9203http://www.repositorio.ufba.br/ri/handle/ri/7603v. 96, n. 1Texto completo: acesso restrito. p. 21–28Various factors have been associated with a predisposition to the development of clinical American visceral leishmaniasis (AVL). However, little information is available about the factors that predispose to asymptomatic infection. To identify the risk factors associated with asymptomatic infection, a study was carried out between July 1997 and June 1998 on children aged 0–5 years in the districts of Vila Nova and Bom Viver in the municipality of Raposa in the island of São Luís, State of Maranhão, Brazil. A questionnaire containing socioeconomic, demographic and epidemiological data was used. The delayedtype hypersensitivity (DTH) test was carried out on 639 children in the first phase, and on 572 in the second, 7 months after the first survey, using Leishmania amazonensis antigen. Infection was determined by enzyme-linked immunosorbent assay (ELISA) in 638 children during the first phase, and in 572 during the second. Six outcome measures were used: initial prevalence, final prevalence and incidence, each determined by DTH and ELISA. The incidence of infection was 10 · 8% when determined by DTH and 28 · 5% when determined by ELISA. After adjustment for confounding variables using Cox regression, infection by L. chagasi was associated with child's age (⩾2 years), location of the dwellings (Vila Nova) and reporting of relatives with AVL. Bathing outside the house and playing outdoors between 18:00 and 20:00 were identified as risk factors in some analyses but not in others. Presence of intra- and peridomestic Lutzomyia sandflies and animals such as dogs or chickens in the house or in the neighbourhood appeared as risk factors in some analyses but in others they unexpectedly seemed to protect from infection. Malnutrition was not found to be associated with infection.Submitted by Suelen Reis (suelen_suzane@hotmail.com) on 2012-12-17T16:27:15Z No. of bitstreams: 1 1-s2.0-S0035920302902270-main.pdf: 1741544 bytes, checksum: db78cc463c35d36a7c1dd1151fc97f91 (MD5)Made available in DSpace on 2012-12-17T16:27:15Z (GMT). No. of bitstreams: 1 1-s2.0-S0035920302902270-main.pdf: 1741544 bytes, checksum: db78cc463c35d36a7c1dd1151fc97f91 (MD5) Previous issue date: 2002http://dx.doi.org/10.1016/S0035-9203(02)90227-0reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAvisceral leishmaniasisLeishmania chagasiasymptomatic infectionchildrenprevalenceincidencerisk factorsBrazilRisk factors associated with asymptomatic infection by Leishmania chagasi in north-east BrazilTransactions of The Royal Society of Tropical Medicine and Hygieneinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINAL1-s2.0-S0035920302902270-main.pdf1-s2.0-S0035920302902270-main.pdfapplication/pdf1741544https://repositorio.ufba.br/bitstream/ri/7603/1/1-s2.0-S0035920302902270-main.pdfdb78cc463c35d36a7c1dd1151fc97f91MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/7603/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT1-s2.0-S0035920302902270-main.pdf.txt1-s2.0-S0035920302902270-main.pdf.txtExtracted texttext/plain43407https://repositorio.ufba.br/bitstream/ri/7603/3/1-s2.0-S0035920302902270-main.pdf.txt1b5738576340d12e70a5e53e2fc71a26MD53ri/76032022-08-08 13:17:40.889oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:40Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Risk factors associated with asymptomatic infection by Leishmania chagasi in north-east Brazil
dc.title.alternative.pt_BR.fl_str_mv Transactions of The Royal Society of Tropical Medicine and Hygiene
title Risk factors associated with asymptomatic infection by Leishmania chagasi in north-east Brazil
spellingShingle Risk factors associated with asymptomatic infection by Leishmania chagasi in north-east Brazil
Caldas, A. J. M.
visceral leishmaniasis
Leishmania chagasi
asymptomatic infection
children
prevalence
incidence
risk factors
Brazil
title_short Risk factors associated with asymptomatic infection by Leishmania chagasi in north-east Brazil
title_full Risk factors associated with asymptomatic infection by Leishmania chagasi in north-east Brazil
title_fullStr Risk factors associated with asymptomatic infection by Leishmania chagasi in north-east Brazil
title_full_unstemmed Risk factors associated with asymptomatic infection by Leishmania chagasi in north-east Brazil
title_sort Risk factors associated with asymptomatic infection by Leishmania chagasi in north-east Brazil
author Caldas, A. J. M.
author_facet Caldas, A. J. M.
Costa, J. M. L.
Silva, A. A. M.
Vinhas, Vera Silvia de Freitas
Barral, Aldina Maria Prado
author_role author
author2 Costa, J. M. L.
Silva, A. A. M.
Vinhas, Vera Silvia de Freitas
Barral, Aldina Maria Prado
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Caldas, A. J. M.
Costa, J. M. L.
Silva, A. A. M.
Vinhas, Vera Silvia de Freitas
Barral, Aldina Maria Prado
Caldas, A. J. M.
Costa, J. M. L.
Silva, A. A. M.
Vinhas, Vera Silvia de Freitas
Barral, Aldina Maria Prado
dc.subject.por.fl_str_mv visceral leishmaniasis
Leishmania chagasi
asymptomatic infection
children
prevalence
incidence
risk factors
Brazil
topic visceral leishmaniasis
Leishmania chagasi
asymptomatic infection
children
prevalence
incidence
risk factors
Brazil
description Texto completo: acesso restrito. p. 21–28
publishDate 2002
dc.date.issued.fl_str_mv 2002
dc.date.accessioned.fl_str_mv 2012-12-17T16:27:15Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/7603
dc.identifier.issn.none.fl_str_mv 0035-9203
dc.identifier.number.pt_BR.fl_str_mv v. 96, n. 1
identifier_str_mv 0035-9203
v. 96, n. 1
url http://www.repositorio.ufba.br/ri/handle/ri/7603
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/S0035-9203(02)90227-0
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
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