Association of cytokines, neurological disability, and disease duration in HAM/TSP patients
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2006 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/5878 |
Resumo: | p.217-221 |
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Muniz, André Luís NunesRodrigues Junior, WaldyrSantos, Silvane Maria BragaJesus, Amélia Maria Ribeiro dePorto, Maria Aurélia da FonsecaCastro, Néviton Matos deOliveira Filho, JamaryAlmeida, Juliana PassosCarvalho, Otavio Augusto Moreno deCarvalho Filho, Edgar Marcelino deMuniz, André Luís NunesRodrigues Junior, WaldyrSantos, Silvane Maria BragaJesus, Amélia Maria Ribeiro dePorto, Maria Aurélia da FonsecaCastro, Néviton Matos deOliveira Filho, JamaryAlmeida, Juliana PassosCarvalho, Otavio Augusto Moreno deCarvalho Filho, Edgar Marcelino de2012-05-16T14:51:45Z2012-05-16T14:51:45Z2006-060004-282Xhttp://www.repositorio.ufba.br/ri/handle/ri/5878v. 64, n. 2-Ap.217-221Objective: To identify clinical and immunological markers associated with HTLV-I associated myelopath y / tropical spastic paraparesis (HAM/TSP). Method: 237 HTLV-I infected individuals were clinically assessed. They were classified according to the Expanded Disability Status Scale (EDSS) and Osame’s Motor Disability Score (OMDS). Cytokine levels were determined in HTLV-I seropositive individuals. Results: 37 patients had HAM/TSP. There was a correlation between the degrees of disability assessed by both scales. There was also a correlation between the duration of HAM/TSP and the severity of disability assessed by either EDSS or OMDS. Higher levels of IFN-were detected in unstimulated peripheral blood mononuclear cells (PBMC) from HAM/TSP patients as compared with HTLV-I carriers. Conclusion: This study shows the validity of the neurological scales to classify the degree of neurological disability in HTLV-I carriers and suggests a pro g ressive behavior of HAM/TSP. This study also shows that IFN-in PBMC supernatants are markers of HAM/TSP.Submitted by Texeira Ana (atanateixeira@gmail.com) on 2012-05-16T14:51:45Z No. of bitstreams: 1 Muniz, André Luiz.pdf: 397193 bytes, checksum: 353ac9e70f674339c8cf516b0af766c8 (MD5)Made available in DSpace on 2012-05-16T14:51:45Z (GMT). No. of bitstreams: 1 Muniz, André Luiz.pdf: 397193 bytes, checksum: 353ac9e70f674339c8cf516b0af766c8 (MD5) Previous issue date: 2006-06São PauloAssociação Arquivos de Neuro-Psiquiatria Dr. Oswaldo Langehttp://dx.doi.org/10.1590/S0004-282X2006000200009reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAHuman T-lymphotropic virus 1Nervous system diseasesCytokinesNeurological disabilityAssociation of cytokines, neurological disability, and disease duration in HAM/TSP patientsArq Neuropsiquiatrinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINALMuniz, André Luiz.pdfMuniz, André Luiz.pdfapplication/pdf397193https://repositorio.ufba.br/bitstream/ri/5878/1/Muniz%2c%20Andr%c3%a9%20Luiz.pdf353ac9e70f674339c8cf516b0af766c8MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5878/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXTMuniz, André Luiz.pdf.txtMuniz, André Luiz.pdf.txtExtracted texttext/plain21792https://repositorio.ufba.br/bitstream/ri/5878/3/Muniz%2c%20Andr%c3%a9%20Luiz.pdf.txtbf98488c858bbd5c38502e2eccd56355MD53ri/58782022-07-05 14:03:12.449oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:12Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Association of cytokines, neurological disability, and disease duration in HAM/TSP patients |
| dc.title.alternative.pt_BR.fl_str_mv |
Arq Neuropsiquiatr |
| title |
Association of cytokines, neurological disability, and disease duration in HAM/TSP patients |
| spellingShingle |
Association of cytokines, neurological disability, and disease duration in HAM/TSP patients Muniz, André Luís Nunes Human T-lymphotropic virus 1 Nervous system diseases Cytokines Neurological disability |
| title_short |
Association of cytokines, neurological disability, and disease duration in HAM/TSP patients |
| title_full |
Association of cytokines, neurological disability, and disease duration in HAM/TSP patients |
| title_fullStr |
Association of cytokines, neurological disability, and disease duration in HAM/TSP patients |
| title_full_unstemmed |
Association of cytokines, neurological disability, and disease duration in HAM/TSP patients |
| title_sort |
Association of cytokines, neurological disability, and disease duration in HAM/TSP patients |
| author |
Muniz, André Luís Nunes |
| author_facet |
Muniz, André Luís Nunes Rodrigues Junior, Waldyr Santos, Silvane Maria Braga Jesus, Amélia Maria Ribeiro de Porto, Maria Aurélia da Fonseca Castro, Néviton Matos de Oliveira Filho, Jamary Almeida, Juliana Passos Carvalho, Otavio Augusto Moreno de Carvalho Filho, Edgar Marcelino de |
| author_role |
author |
| author2 |
Rodrigues Junior, Waldyr Santos, Silvane Maria Braga Jesus, Amélia Maria Ribeiro de Porto, Maria Aurélia da Fonseca Castro, Néviton Matos de Oliveira Filho, Jamary Almeida, Juliana Passos Carvalho, Otavio Augusto Moreno de Carvalho Filho, Edgar Marcelino de |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Muniz, André Luís Nunes Rodrigues Junior, Waldyr Santos, Silvane Maria Braga Jesus, Amélia Maria Ribeiro de Porto, Maria Aurélia da Fonseca Castro, Néviton Matos de Oliveira Filho, Jamary Almeida, Juliana Passos Carvalho, Otavio Augusto Moreno de Carvalho Filho, Edgar Marcelino de Muniz, André Luís Nunes Rodrigues Junior, Waldyr Santos, Silvane Maria Braga Jesus, Amélia Maria Ribeiro de Porto, Maria Aurélia da Fonseca Castro, Néviton Matos de Oliveira Filho, Jamary Almeida, Juliana Passos Carvalho, Otavio Augusto Moreno de Carvalho Filho, Edgar Marcelino de |
| dc.subject.por.fl_str_mv |
Human T-lymphotropic virus 1 Nervous system diseases Cytokines Neurological disability |
| topic |
Human T-lymphotropic virus 1 Nervous system diseases Cytokines Neurological disability |
| description |
p.217-221 |
| publishDate |
2006 |
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2006-06 |
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2012-05-16T14:51:45Z |
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2012-05-16T14:51:45Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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http://www.repositorio.ufba.br/ri/handle/ri/5878 |
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0004-282X |
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v. 64, n. 2-A |
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0004-282X v. 64, n. 2-A |
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Associação Arquivos de Neuro-Psiquiatria Dr. Oswaldo Lange |
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Associação Arquivos de Neuro-Psiquiatria Dr. Oswaldo Lange |
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http://dx.doi.org/10.1590/S0004-282X2006000200009 |
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