Characteristics of lipid micro- and nanoparticles based on supercritical formation for potential pharmaceutical application

Detalhes bibliográficos
Autor(a) principal: Santo, Islane Espírito
Data de Publicação: 2013
Outros Autores: Pedro, André São, Fialho, Rosana, Albuquerque, Elaine Christine de Magalhães Cabral
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15306
Resumo: p. 1-17
id UFBA-2_f8bb52b1cf6a060ca00449cd2cca67a0
oai_identifier_str oai:repositorio.ufba.br:ri/15306
network_acronym_str UFBA-2
network_name_str Repositório Institucional da UFBA
repository_id_str 1932
spelling Santo, Islane EspíritoPedro, André SãoFialho, RosanaAlbuquerque, Elaine Christine de Magalhães CabralSanto, Islane EspíritoPedro, André SãoFialho, RosanaAlbuquerque, Elaine Christine de Magalhães Cabral2014-07-28T14:25:02Z2014-07-28T14:25:02Z20131931-7573http://repositorio.ufba.br/ri/handle/ri/15306v. 8, n. 1p. 1-17The interest of the pharmaceutical industry in lipid drug delivery systems due to their prolonged release profile, biocompatibility, reduction of side effects, and so on is already known. However, conventional methods of preparation of these structures for their use and production in the pharmaceutical industry are difficult since these methods are usually multi-step and involve high amount of organic solvent. Furthermore, some processes need extreme conditions, which can lead to an increase of heterogeneity of particle size and degradation of the drug. An alternative for drug delivery system production is the utilization of supercritical fluid technique. Lipid particles produced by supercritical fluid have shown different physicochemical properties in comparison to lipid particles produced by classical methods. Such particles have shown more physical stability and narrower size distribution. So, in this paper, a critical overview of supercritical fluid-based processes for the production of lipid micro- and nanoparticles is given and the most important characteristics of each process are highlighted.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-04-07T13:43:10Z No. of bitstreams: 1 10.11861556-276X-8-386.pdf: 1618452 bytes, checksum: 5b9bc5564bdb611af84ea9d455e3df7e (MD5)Approved for entry into archive by LIVIA FREITAS (livia.freitas@ufba.br) on 2014-07-28T14:25:02Z (GMT) No. of bitstreams: 1 10.11861556-276X-8-386.pdf: 1618452 bytes, checksum: 5b9bc5564bdb611af84ea9d455e3df7e (MD5)Made available in DSpace on 2014-07-28T14:25:02Z (GMT). No. of bitstreams: 1 10.11861556-276X-8-386.pdf: 1618452 bytes, checksum: 5b9bc5564bdb611af84ea9d455e3df7e (MD5) Previous issue date: 2013http://dx.doi.org/10.1186/1556-276X-8-386reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBALiposomesSolid lipid nanoparticlesSupercritical carbon dioxideCharacteristics of lipid micro- and nanoparticles based on supercritical formation for potential pharmaceutical applicationNanoscale Research LettersArtigo de Periódicoinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionBrasilinfo:eu-repo/semantics/openAccessengORIGINAL10.11861556-276X-8-386.pdf10.11861556-276X-8-386.pdfapplication/pdf1618452https://repositorio.ufba.br/bitstream/ri/15306/1/10.11861556-276X-8-386.pdf5b9bc5564bdb611af84ea9d455e3df7eMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/15306/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52TEXT10.11861556-276X-8-386.pdf.txt10.11861556-276X-8-386.pdf.txtExtracted texttext/plain73345https://repositorio.ufba.br/bitstream/ri/15306/3/10.11861556-276X-8-386.pdf.txta824f1dc2a5c9411a14d1c8623555fb4MD53ri/153062022-08-26 11:47:07.651oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-26T14:47:07Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Characteristics of lipid micro- and nanoparticles based on supercritical formation for potential pharmaceutical application
dc.title.alternative.pt_BR.fl_str_mv Nanoscale Research Letters
title Characteristics of lipid micro- and nanoparticles based on supercritical formation for potential pharmaceutical application
spellingShingle Characteristics of lipid micro- and nanoparticles based on supercritical formation for potential pharmaceutical application
Santo, Islane Espírito
Liposomes
Solid lipid nanoparticles
Supercritical carbon dioxide
title_short Characteristics of lipid micro- and nanoparticles based on supercritical formation for potential pharmaceutical application
title_full Characteristics of lipid micro- and nanoparticles based on supercritical formation for potential pharmaceutical application
title_fullStr Characteristics of lipid micro- and nanoparticles based on supercritical formation for potential pharmaceutical application
title_full_unstemmed Characteristics of lipid micro- and nanoparticles based on supercritical formation for potential pharmaceutical application
title_sort Characteristics of lipid micro- and nanoparticles based on supercritical formation for potential pharmaceutical application
author Santo, Islane Espírito
author_facet Santo, Islane Espírito
Pedro, André São
Fialho, Rosana
Albuquerque, Elaine Christine de Magalhães Cabral
author_role author
author2 Pedro, André São
Fialho, Rosana
Albuquerque, Elaine Christine de Magalhães Cabral
author2_role author
author
author
dc.contributor.author.fl_str_mv Santo, Islane Espírito
Pedro, André São
Fialho, Rosana
Albuquerque, Elaine Christine de Magalhães Cabral
Santo, Islane Espírito
Pedro, André São
Fialho, Rosana
Albuquerque, Elaine Christine de Magalhães Cabral
dc.subject.por.fl_str_mv Liposomes
Solid lipid nanoparticles
Supercritical carbon dioxide
topic Liposomes
Solid lipid nanoparticles
Supercritical carbon dioxide
description p. 1-17
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2014-07-28T14:25:02Z
dc.date.available.fl_str_mv 2014-07-28T14:25:02Z
dc.type.driver.fl_str_mv Artigo de Periódico
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15306
dc.identifier.issn.none.fl_str_mv 1931-7573
dc.identifier.number.pt_BR.fl_str_mv v. 8, n. 1
identifier_str_mv 1931-7573
v. 8, n. 1
url http://repositorio.ufba.br/ri/handle/ri/15306
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.country.fl_str_mv Brasil
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1186/1556-276X-8-386
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/15306/1/10.11861556-276X-8-386.pdf
https://repositorio.ufba.br/bitstream/ri/15306/2/license.txt
https://repositorio.ufba.br/bitstream/ri/15306/3/10.11861556-276X-8-386.pdf.txt
bitstream.checksum.fl_str_mv 5b9bc5564bdb611af84ea9d455e3df7e
0d4b811ef71182510d2015daa7c8a900
a824f1dc2a5c9411a14d1c8623555fb4
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv
_version_ 1801502534665240576

Registros relacionados