Investigation of resistance of Salmonella spp. isolated from products and raw material of animal origin (swine and poultry)to antibiotics and disinfectants

• Main Author: Maciel,Mônica Jachetti
• Publication Date: 2019
• Other Authors: Machado,Gustavo, Avancini,Cesar Augusto Marchionatti
• Format: Article
• Language: eng
• Source: Revista Brasileira de Saúde e Produção Animal
• Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-99402019000100400
• topic: antimicrobial resistance; simultaneous resistance; Salmonella

ABSTRACT The genus Salmonella spp. Has worldwide geographical distribution, and represents a potential risk both to animal and human health. Inadequate use as well as continuous exposure to antibiotics and disinfectants might lead to the appearance of resistance of these microorganisms to antimicrobial compounds. The aims of this study were to investigate the occurrence of resistance in Salmonella spp., isolated from products and raw material of animal origin (swine and poultry), to antibiotics and disinfectants, and check whether the phenomenon of simultaneous resistance to disinfectants occurs among the antibiotic-resistant isolates. The test of susceptibility to antimicrobials (TSA) applied in 134 isolates indicated that 51 (38%) were resistant to at least one of the eight antibiotics used, and 28 (55%) of resistant isolates were multi-resistant. Resistant isolates were submitted to the test of quantitative suspension against four concentrations of disinfectants in three contact times, and the result was compared with that of the reference strain (Salmonella Choleraesuis ATCC 10.708). While the reference strain was sensitive considering the highest concentration (200 ppm) and the lowest contact time (5 min) as indicators, 12 (24%) isolates were resistant to cetyltrimethylammonium chloride (ammonia quaternary); the reference strain was resistant to chlorhexidine, which also occurred with 22 (43%) of the isolates; similar to the reference strain, all isolates were sensitive/inactivated by sodium hypochlorite and iodophore. There were no significant relations of simultaneous resistance between the antibiotics and the disinfectants tested.