Determining anthelmintic residues in goat milk in Brazil

• Autor(a) principal: PORTO FILHO,José Matias
• Data de Publicação: 2019
• Outros Autores: COSTA,Roberto Germano, ARAÚJO,Adélia Cristina Pessoa, ALBUQUERQUE JÚNIOR,Eden Cavalcanti, CUNHA,Adriano Nunes, CRUZ,George Rodrigo Beltrão da
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista Brasileira de Saúde e Produção Animal
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-99402019000100814
• topic: Goats; mass spectrometry; maximum residue limit; moxidectin; ivermectin

SUMMARY Anthelmintics are used to combat nematodes. The misuse of anthelmintics can raise the cost of milk production. The objective of this research was to determine the presence of anthelmintics in goat milk. Twenty goats were used, divided into four groups of five animals: I- animals treated with an ivermectin-based anthelmintic; II- animals treated with moxidectin; III- animals treated with levamisole hydrochloride; and IV: animals treated with albendazole. Milk samples were collected individually: before, and 1, 2, 3, 15 and 21 days after administration of the anthelmintics. Determination of anthelmintic residues was performed by liquid chromatography-mass spectrometry (LC-MS). According to the results, there was an exponential effect (P<0.05) for ivermectin and moxidectin. Moxidectin was the anthelmintic that left a residue in the milk for the longest time, up to 21 days. However, with all the anthelmintics researched, residues were below the maximum limit recommended by the inspecting agencies.