Effectiveness of metronidazole in the treatment of tumor wound odors
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng por |
Título da fonte: | Rev Rene (Online) |
Texto Completo: | http://periodicos.ufc.br/rene/article/view/31410 |
Resumo: | Objective: to analyze the evidence of the effectiveness of Metronidazole in the treatment of odors in tumor wounds. Methods: this is an integrative review performed at the health databases and the PubMed portal. The studies were evaluated by the Jadad Scale (randomized clinical trials), Downs and Black (quasi-experiment) and the Strengthening the Reporting of Observational studies in Epidemiology (observational). A sample of the ten studies and articles were considered cut-off points that reached 50.0% of the criteria. Results: Metronidazole was effective in 95.6% of the cases and the gel preparation at 0.75% was the most used in the studies. Conclusion: the evidence indicates that metronidazole is safe and effective in the control of tumor wound odors, but there is no consensus on the most effective forms of presentation and administration routes. Most studies associate the appearance of bad odor with the growth of anaerobic bacteria in the tumor tissue. |
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Effectiveness of metronidazole in the treatment of tumor wound odorsEfetividade do metronidazol no tratamento de odores em feridas tumoraisWounds and Injuries; Odorants; Metronidazole; Neoplasms.Ferimentos e Lesões; Odorantes; Metronidazol; Neoplasias.Objective: to analyze the evidence of the effectiveness of Metronidazole in the treatment of odors in tumor wounds. Methods: this is an integrative review performed at the health databases and the PubMed portal. The studies were evaluated by the Jadad Scale (randomized clinical trials), Downs and Black (quasi-experiment) and the Strengthening the Reporting of Observational studies in Epidemiology (observational). A sample of the ten studies and articles were considered cut-off points that reached 50.0% of the criteria. Results: Metronidazole was effective in 95.6% of the cases and the gel preparation at 0.75% was the most used in the studies. Conclusion: the evidence indicates that metronidazole is safe and effective in the control of tumor wound odors, but there is no consensus on the most effective forms of presentation and administration routes. Most studies associate the appearance of bad odor with the growth of anaerobic bacteria in the tumor tissue.Objetivo: analisar as evidências da efetividade do Metronidazol no tratamento de odores em feridas tumorais. Métodos: revisão integrativa realizada nas bases de saúde e no portal PubMed. Os estudos foram avaliados pela Escala de Jadad (ensaios clínicos randomizados), Downs e Black (quase experimentais) e o Strengthening the Reporting of Observational studies in Epidemiology (observacionais). Amostra de dez estudos e considerou-se como ponto de corte artigos que atingiram 50,0% dos critérios. Resultados: o Metronidazol se mostrou efetivo em 95,6% dos casos e a preparação em gel a 0,75% foi a mais utilizada nos estudos. Conclusão:as evidências apontam o metronidazol como seguro e eficaz no controle de odores em feridas tumorais, porém não há consenso sobre as formas de apresentação e vias de administração mais efetivas. A maioria dos estudos associa o surgimento de mau odor com o crescimento de bactérias anaeróbias no tecido tumoral.Universidade Federal do Ceará2018-05-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionrevisão integrativa application/pdfapplication/pdfhttp://periodicos.ufc.br/rene/article/view/3141010.15253/2175-6783.2018193245Rev Rene; Vol 19 (2018): Rev Rene; e3245Rev Rene; v. 19 (2018): Rev Rene; e32452175-67831517-3852reponame:Rev Rene (Online)instname:Universidade Federal do Ceará (UFC)instacron:UFCengporhttp://periodicos.ufc.br/rene/article/view/31410/71873http://periodicos.ufc.br/rene/article/view/31410/pdfCopyright (c) 2018 Rev Renehttps://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessBarreto, Arthur MonteMarques, Antonio Dean BarbosaCestari, Virna Ribeiro FeitosaCavalcante, Rochelle da CostaMoreira, Thereza Maria Magalhães2020-05-28T15:35:25Zoai:periodicos.ufc:article/31410Revistahttp://periodicos.ufc.br/renePUBhttp://periodicos.ufc.br/rene/oairene@ufc.br||2175-67831517-3852opendoar:2020-05-28T15:35:25Rev Rene (Online) - Universidade Federal do Ceará (UFC)false |
dc.title.none.fl_str_mv |
Effectiveness of metronidazole in the treatment of tumor wound odors Efetividade do metronidazol no tratamento de odores em feridas tumorais |
title |
Effectiveness of metronidazole in the treatment of tumor wound odors |
spellingShingle |
Effectiveness of metronidazole in the treatment of tumor wound odors Barreto, Arthur Monte Wounds and Injuries; Odorants; Metronidazole; Neoplasms. Ferimentos e Lesões; Odorantes; Metronidazol; Neoplasias. |
title_short |
Effectiveness of metronidazole in the treatment of tumor wound odors |
title_full |
Effectiveness of metronidazole in the treatment of tumor wound odors |
title_fullStr |
Effectiveness of metronidazole in the treatment of tumor wound odors |
title_full_unstemmed |
Effectiveness of metronidazole in the treatment of tumor wound odors |
title_sort |
Effectiveness of metronidazole in the treatment of tumor wound odors |
author |
Barreto, Arthur Monte |
author_facet |
Barreto, Arthur Monte Marques, Antonio Dean Barbosa Cestari, Virna Ribeiro Feitosa Cavalcante, Rochelle da Costa Moreira, Thereza Maria Magalhães |
author_role |
author |
author2 |
Marques, Antonio Dean Barbosa Cestari, Virna Ribeiro Feitosa Cavalcante, Rochelle da Costa Moreira, Thereza Maria Magalhães |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Barreto, Arthur Monte Marques, Antonio Dean Barbosa Cestari, Virna Ribeiro Feitosa Cavalcante, Rochelle da Costa Moreira, Thereza Maria Magalhães |
dc.subject.por.fl_str_mv |
Wounds and Injuries; Odorants; Metronidazole; Neoplasms. Ferimentos e Lesões; Odorantes; Metronidazol; Neoplasias. |
topic |
Wounds and Injuries; Odorants; Metronidazole; Neoplasms. Ferimentos e Lesões; Odorantes; Metronidazol; Neoplasias. |
description |
Objective: to analyze the evidence of the effectiveness of Metronidazole in the treatment of odors in tumor wounds. Methods: this is an integrative review performed at the health databases and the PubMed portal. The studies were evaluated by the Jadad Scale (randomized clinical trials), Downs and Black (quasi-experiment) and the Strengthening the Reporting of Observational studies in Epidemiology (observational). A sample of the ten studies and articles were considered cut-off points that reached 50.0% of the criteria. Results: Metronidazole was effective in 95.6% of the cases and the gel preparation at 0.75% was the most used in the studies. Conclusion: the evidence indicates that metronidazole is safe and effective in the control of tumor wound odors, but there is no consensus on the most effective forms of presentation and administration routes. Most studies associate the appearance of bad odor with the growth of anaerobic bacteria in the tumor tissue. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-05-07 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion revisão integrativa |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://periodicos.ufc.br/rene/article/view/31410 10.15253/2175-6783.2018193245 |
url |
http://periodicos.ufc.br/rene/article/view/31410 |
identifier_str_mv |
10.15253/2175-6783.2018193245 |
dc.language.iso.fl_str_mv |
eng por |
language |
eng por |
dc.relation.none.fl_str_mv |
http://periodicos.ufc.br/rene/article/view/31410/71873 http://periodicos.ufc.br/rene/article/view/31410/pdf |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Rev Rene https://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Rev Rene https://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal do Ceará |
publisher.none.fl_str_mv |
Universidade Federal do Ceará |
dc.source.none.fl_str_mv |
Rev Rene; Vol 19 (2018): Rev Rene; e3245 Rev Rene; v. 19 (2018): Rev Rene; e3245 2175-6783 1517-3852 reponame:Rev Rene (Online) instname:Universidade Federal do Ceará (UFC) instacron:UFC |
instname_str |
Universidade Federal do Ceará (UFC) |
instacron_str |
UFC |
institution |
UFC |
reponame_str |
Rev Rene (Online) |
collection |
Rev Rene (Online) |
repository.name.fl_str_mv |
Rev Rene (Online) - Universidade Federal do Ceará (UFC) |
repository.mail.fl_str_mv |
rene@ufc.br|| |
_version_ |
1797174733185220608 |