Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFG |
Texto Completo: | http://repositorio.bc.ufg.br/tede/handle/tede/9178 |
Resumo: | The aim of this study was to assess and compare the influence of Visual Field (VF) and/or Optical Coherence Tomography (OCT) when analyzed in association with Color Retinography (CR) to differentiate glaucomatous patients from those with increased physiological cupping, by non-glaucoma specialists. Eighty patients were selected, half with glaucoma and half with physiological cupping. The patients were randomized into 4 groups according to the exam performed on their right eye, which would be shown through Power Point slides to 20 non-specialist ophthalmologists: GI (CR), GII (CR + VF), GIII (CR + OCT), GIV (CR + VF + OCT). The ophthalmologists completed a questionnaire in which they checked whether or not the patient was glaucomatous, without direct examination of the patient. Inter-rater agreement determined by Kappa test was good for GII (k: 0.63; 95% CI,0.53-0.72), moderate for GIII (k:0.58; 95% CI,0.48-0.68) and for GIV (k: 0.41; 95% CI,0.31-0.51) and low for GI (k:0.30; 95% CI,0.20-0.39), the difference among groups being statistically significant (p<0.001). Statistically significant difference was found regarding correct diagnoses among groups, GIII being higher (15.8 ± 1.82) in comparison with GI (12.95 ± 1.46), (p<0.001); and higher for GII (16.25 ± 2.02) when compared to GI and GIV (14.10 ± 2.24), for both p<0.001. We found higher values for GII and GIII (p<0.001) regarding correct diagnoses of slides with glaucomatous patients single-handedly. Sensitivity and Specificity for each group were respectively: GI (59% and 70.5%); GII (86.5% and 76%); GIII (86.5% and 71.5%); GIV (68.5% and 72.5%). Accuracy was higher for GII 81.3% (95% CI,77.1-84.8), followed by GIII 79% (95% CI,74.7-82.7), GIV 70,5% (95% CI,65.9-74.8) and lower for GI 64.8% (95% CI, 60.0-69.3). We concluded that isolated assessment of CR by non-glaucoma specialists failed to properly differentiate glaucomatous patients from those with increased physiological cupping. We detected a significant increase in diagnostic accuracy and inter-rater agreement when either VF or OCT is employed. Increase for Sensitivity and Specificity was not detected for both. |
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Silva, Leopoldo Magacho dos Santoshttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4234054Y4Silva, Leopoldo Magacho dos SantosPaula, Alcio Coutinho deIsaac, David Leonardo CruvinelPereira, Luciano de Sousahttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4205895P7Franco, Cláudia Gomide Vilela de Sousa2018-12-21T10:26:50Z2018-11-19FRANCO, Cláudia Gomide Vilela de Sousa. Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma. 2018. 65 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2018.http://repositorio.bc.ufg.br/tede/handle/tede/9178The aim of this study was to assess and compare the influence of Visual Field (VF) and/or Optical Coherence Tomography (OCT) when analyzed in association with Color Retinography (CR) to differentiate glaucomatous patients from those with increased physiological cupping, by non-glaucoma specialists. Eighty patients were selected, half with glaucoma and half with physiological cupping. The patients were randomized into 4 groups according to the exam performed on their right eye, which would be shown through Power Point slides to 20 non-specialist ophthalmologists: GI (CR), GII (CR + VF), GIII (CR + OCT), GIV (CR + VF + OCT). The ophthalmologists completed a questionnaire in which they checked whether or not the patient was glaucomatous, without direct examination of the patient. Inter-rater agreement determined by Kappa test was good for GII (k: 0.63; 95% CI,0.53-0.72), moderate for GIII (k:0.58; 95% CI,0.48-0.68) and for GIV (k: 0.41; 95% CI,0.31-0.51) and low for GI (k:0.30; 95% CI,0.20-0.39), the difference among groups being statistically significant (p<0.001). Statistically significant difference was found regarding correct diagnoses among groups, GIII being higher (15.8 ± 1.82) in comparison with GI (12.95 ± 1.46), (p<0.001); and higher for GII (16.25 ± 2.02) when compared to GI and GIV (14.10 ± 2.24), for both p<0.001. We found higher values for GII and GIII (p<0.001) regarding correct diagnoses of slides with glaucomatous patients single-handedly. Sensitivity and Specificity for each group were respectively: GI (59% and 70.5%); GII (86.5% and 76%); GIII (86.5% and 71.5%); GIV (68.5% and 72.5%). Accuracy was higher for GII 81.3% (95% CI,77.1-84.8), followed by GIII 79% (95% CI,74.7-82.7), GIV 70,5% (95% CI,65.9-74.8) and lower for GI 64.8% (95% CI, 60.0-69.3). We concluded that isolated assessment of CR by non-glaucoma specialists failed to properly differentiate glaucomatous patients from those with increased physiological cupping. We detected a significant increase in diagnostic accuracy and inter-rater agreement when either VF or OCT is employed. Increase for Sensitivity and Specificity was not detected for both.O objetivo deste estudo foi verificar a influência do campo visual (CV) e/ou tomografia de coerência óptica (TCO), quando analisados em associação à retinografia colorida (RC), na diferenciação entre indivíduos com glaucoma daqueles com aumento fisiológico de escavação, por oftalmologistas não especialistas em glaucoma. Foram selecionados 80 pacientes, metade deles com glaucoma e metade com aumento fisiológico da escavação. Os pacientes foram randomizados em 4 grupos de acordo com os exames do olho direito, que foram mostrados em slides numerados do Power Point para 20 oftalmologistas não especialistas: GI (RC), GII (RC + CV), GIII (RC + TCO), GIV (RC + CV + TCO). Os oftalmologistas responderam a um questionário na qual assinalavam se o paciente tinha glaucoma ou não, sem o exame direto do paciente. A concordância (kappa) interobservador foi boa no GII (κ: 0,63; 95% IC, 0,53-0,72), moderada no GIII (κ: 0,58; 95% IC, 0,48-0,68) e GIV (κ: 0,41; 95% IC, 0,31-0,51) e baixa no GI (κ: 0,30; 95% IC, 0,20-0,39); a diferença entre os grupos foi significativa (p<0,001). Em relação ao número total de acertos, houve diferença significativa na comparação entre os grupos: o GIII (15,8 ± 1,82) foi superior em relação ao GI (12,95 ± 1,46), (p<0,001); e o GII (16,25 ± 2,02) superior em relação aos GI e GIV (14,10 ± 2,24), para ambos, p<0,001. Em relação aos acertos referentes apenas aos slides de pacientes com glaucoma, encontrou-se que GII e GIII foram superiores a GI e GIV (p<0,001). A sensibilidade (Se) e especificidade (Es) em cada grupo foram respectivamente: GI (59% e 70,5%); GII (86,5% e 76%); GIII (86,5% e 71,5%); GIV (68,5% e 72,5%). A acurácia foi maior no GII 81,3% (95% IC, 77,1-84,8), seguido pelo GIII 79% (95% IC, 74,7-82,7), GIV 70,5% (95% IC, 65,9-74,8) e menor no GI 64,8% (95% IC, 60,0- 69,3). Conclui-se que a avaliação isolada da RC por oftalmologistas não especialistas em glaucoma foi pouco sensível em discriminar pacientes glaucomatosos daqueles com aumento fisiológico de escavação. Notou-se significativo aumento na habilidade diagnóstica e na concordância interexaminador quando há a associação do CV ou TCO. Não houve aumento de Se e Es com ambos.Submitted by Marlene Santos (marlene.bc.ufg@gmail.com) on 2018-12-18T17:00:40Z No. of bitstreams: 2 Dissertação - Cláudia Gomide Vilela de Sousa Franco - 2018.pdf: 2504961 bytes, checksum: 3d5f9b9adba46fd17cd268a418694fc9 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2018-12-21T10:26:50Z (GMT) No. of bitstreams: 2 Dissertação - Cláudia Gomide Vilela de Sousa Franco - 2018.pdf: 2504961 bytes, checksum: 3d5f9b9adba46fd17cd268a418694fc9 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Made available in DSpace on 2018-12-21T10:26:50Z (GMT). No. of bitstreams: 2 Dissertação - Cláudia Gomide Vilela de Sousa Franco - 2018.pdf: 2504961 bytes, checksum: 3d5f9b9adba46fd17cd268a418694fc9 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2018-11-19Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfporUniversidade Federal de GoiásPrograma de Pós-graduação em Ciências da Saúde (FM)UFGBrasilFaculdade de Medicina - FM (RG)http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessGlaucomaTomografia de coerência ópticaTestes de campo visualDisco ópticoVariações dependentes de observadorOptical coherence tomographyVisual field testsOptic diskObserver variationCIENCIAS DA SAUDE::MEDICINAInfluência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucomaInfluence of computerized campimetry, optical coherence tomography or both in glaucoma diagnosis by ophthalmologist not specialized in glaucomainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis-10068643126177453106006006006001545772475950486338-9693694523087866272075167498588264571reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; 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dc.title.eng.fl_str_mv |
Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma |
dc.title.alternative.eng.fl_str_mv |
Influence of computerized campimetry, optical coherence tomography or both in glaucoma diagnosis by ophthalmologist not specialized in glaucoma |
title |
Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma |
spellingShingle |
Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma Franco, Cláudia Gomide Vilela de Sousa Glaucoma Tomografia de coerência óptica Testes de campo visual Disco óptico Variações dependentes de observador Optical coherence tomography Visual field tests Optic disk Observer variation CIENCIAS DA SAUDE::MEDICINA |
title_short |
Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma |
title_full |
Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma |
title_fullStr |
Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma |
title_full_unstemmed |
Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma |
title_sort |
Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma |
author |
Franco, Cláudia Gomide Vilela de Sousa |
author_facet |
Franco, Cláudia Gomide Vilela de Sousa |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Silva, Leopoldo Magacho dos Santos |
dc.contributor.advisor1Lattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4234054Y4 |
dc.contributor.referee1.fl_str_mv |
Silva, Leopoldo Magacho dos Santos |
dc.contributor.referee2.fl_str_mv |
Paula, Alcio Coutinho de |
dc.contributor.referee3.fl_str_mv |
Isaac, David Leonardo Cruvinel |
dc.contributor.referee4.fl_str_mv |
Pereira, Luciano de Sousa |
dc.contributor.authorLattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4205895P7 |
dc.contributor.author.fl_str_mv |
Franco, Cláudia Gomide Vilela de Sousa |
contributor_str_mv |
Silva, Leopoldo Magacho dos Santos Silva, Leopoldo Magacho dos Santos Paula, Alcio Coutinho de Isaac, David Leonardo Cruvinel Pereira, Luciano de Sousa |
dc.subject.por.fl_str_mv |
Glaucoma Tomografia de coerência óptica Testes de campo visual Disco óptico Variações dependentes de observador |
topic |
Glaucoma Tomografia de coerência óptica Testes de campo visual Disco óptico Variações dependentes de observador Optical coherence tomography Visual field tests Optic disk Observer variation CIENCIAS DA SAUDE::MEDICINA |
dc.subject.eng.fl_str_mv |
Optical coherence tomography Visual field tests Optic disk Observer variation |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE::MEDICINA |
description |
The aim of this study was to assess and compare the influence of Visual Field (VF) and/or Optical Coherence Tomography (OCT) when analyzed in association with Color Retinography (CR) to differentiate glaucomatous patients from those with increased physiological cupping, by non-glaucoma specialists. Eighty patients were selected, half with glaucoma and half with physiological cupping. The patients were randomized into 4 groups according to the exam performed on their right eye, which would be shown through Power Point slides to 20 non-specialist ophthalmologists: GI (CR), GII (CR + VF), GIII (CR + OCT), GIV (CR + VF + OCT). The ophthalmologists completed a questionnaire in which they checked whether or not the patient was glaucomatous, without direct examination of the patient. Inter-rater agreement determined by Kappa test was good for GII (k: 0.63; 95% CI,0.53-0.72), moderate for GIII (k:0.58; 95% CI,0.48-0.68) and for GIV (k: 0.41; 95% CI,0.31-0.51) and low for GI (k:0.30; 95% CI,0.20-0.39), the difference among groups being statistically significant (p<0.001). Statistically significant difference was found regarding correct diagnoses among groups, GIII being higher (15.8 ± 1.82) in comparison with GI (12.95 ± 1.46), (p<0.001); and higher for GII (16.25 ± 2.02) when compared to GI and GIV (14.10 ± 2.24), for both p<0.001. We found higher values for GII and GIII (p<0.001) regarding correct diagnoses of slides with glaucomatous patients single-handedly. Sensitivity and Specificity for each group were respectively: GI (59% and 70.5%); GII (86.5% and 76%); GIII (86.5% and 71.5%); GIV (68.5% and 72.5%). Accuracy was higher for GII 81.3% (95% CI,77.1-84.8), followed by GIII 79% (95% CI,74.7-82.7), GIV 70,5% (95% CI,65.9-74.8) and lower for GI 64.8% (95% CI, 60.0-69.3). We concluded that isolated assessment of CR by non-glaucoma specialists failed to properly differentiate glaucomatous patients from those with increased physiological cupping. We detected a significant increase in diagnostic accuracy and inter-rater agreement when either VF or OCT is employed. Increase for Sensitivity and Specificity was not detected for both. |
publishDate |
2018 |
dc.date.accessioned.fl_str_mv |
2018-12-21T10:26:50Z |
dc.date.issued.fl_str_mv |
2018-11-19 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
FRANCO, Cláudia Gomide Vilela de Sousa. Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma. 2018. 65 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2018. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tede/9178 |
identifier_str_mv |
FRANCO, Cláudia Gomide Vilela de Sousa. Influência da campimetria computadorizada, da tomografia de coerência óptica, ou ambas, no diagnóstico do glaucoma por oftalmologistas não especialistas em glaucoma. 2018. 65 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2018. |
url |
http://repositorio.bc.ufg.br/tede/handle/tede/9178 |
dc.language.iso.fl_str_mv |
por |
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