HEMATOLOGICAL OBSERVATIONS IN THE BLOOD AND BONE MARROW OF DOGS NATURALLY INFECTED BY Ehrlichia spp. AND Anaplasma spp.

• Autor(a) principal: Holanda, Lidiana Carvalho de
• Data de Publicação: 2019
• Outros Autores: Craveiro de Almeida, Telga Lucena Alves, de Mesquita, Rebeca Menelau, de Oliveira, Júnior Mario Baltazar, Oliveira, Andréa Alice da Fonseca
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Ciência animal brasileira (Online)
• Texto Completo: https://revistas.ufg.br/vet/article/view/47686

This study aimed to analyze the hematological and cytomorphological findings in the peripheral blood and bone marrow of dogs infected with Ehrlichia spp. and Anaplasma spp. Forty-four dogs with clinically suspected hemoparasitosis, belonging to different breeds, ages, and both sexes, underwent serological examination by SNAP Assay, hematological analysis, and myelogram. Among them, 63.6% (28/44) tested serologically positive; among the serologically positive dogs, 57.1% (16/28) tested positive for Ehrlichia spp., 21.4% (6/28) for Anaplasma spp., and 21.4% (6/28) were coinfected. Thrombocytopenia was the most frequent hematologic alteration in dogs positive for Ehrlichia spp., present in 93.7% (15/16) (p=0.015) of the infected animals, while macrocytic and hypochromic anemia were observed in 66.7% (4/6) (p=0.010) of the animals infected with Anaplasma spp. In the myelogram, 62.5% (10/16, p=0.005) and 75.0% (12/16, p=0,044) of the animals positive for Ehrlichia spp. presented with bone marrow hypoplasia and decrease in the myeloid: erythroid (M:E) ratio, respectively. Hyperplasia of the erythroid series was observed in 50.0% (3/6) (p=0.022) of the animals positive for Anaplasma spp. No significant association was observed between the hematological alterations and the coinfection group (p>0.05). On the basis of these hematological observations, it can be inferred that the aforementioned laboratory examinations could be employed for the characterization and confirmative diagnosis of hemoparasitosis in dogs. Keywords: hematological analysis, hemoparasitosis, immunodiagnostic, myelogram.