Enfermidades Cutâneas Digitais Bovina: Aspectos Genéticos E Terapêuticos
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFG |
Texto Completo: | http://repositorio.bc.ufg.br/tede/handle/tde/1121 |
Resumo: | This study has aimed do evaluate a risk factor for bovine digital dermatitis and the efficacy of 5% aqueous barbatimão extract solution as ancillary in interdigital skin incisional wound repair. One hundred bovine females, 50 Holstein and 50 Girolando, from two different farms were used for the risk factor study. Experimental units were divided into four groups: healthy Holstein cattle group (GHS) and digital dermatitis Holstein cattle group (GHL), healthy Girolando cattle group (GGS) and digital dermatitis Girolando cattle group (GGL). Ten milliliters of blood were collected from all animals and stored in anticoagulant added tubes. Samples were refrigerated and submitted to hemolytic tests for eight bovine blood systems: A, B, C, F, J, L, S and Z. The frequency of blood factors was determined and compared, in each system and each group. Data were analyzed through non parametric tests: Chi Square and Fisher s exact. The results indicated that the blood factors may contribute to the occurrence of digital dermatitis lesions, but further studies are needed for a more accurate conclusion. Thirty confined, 10 months old calves were selected in order to evaluate the efficacy of 5% barbatimão solution. A biopsy punch was introduced in each interdigital space, up to the dermis, to produce a lesion measuring one centimeter in diameter. The lesions were numbered 120 in total and named experimental units, which were divided into two groups of 60 units each: GB treated with 5% aqueous barbatimão bark extract solution and GC treated with water. Tissue repair was evaluated through macroscopic and histological findings in days three, seven, 14 and 21 of treatment. Macroscopic findings were analyzed descriptively, while histological findings were submitted to Mann Whitney test, with p<0.05. For lesions treated, GB group showed less intense polymorphonuclear cells infiltration on the first 14 days of treatment. A marked collagen deposition was also observed at day 14 while collagen alignment was more expressive on day 21. More specific studies may be necessary in order to determine if blood factors can contribute to the occurrence of digital dermatitis. Barbatiman 5% footbath solution for confined cattle helps qualitatively in modulation of interdigital cutaneous incisional wound repair, but does not avoid the extension of inflammatory phase of healing. |
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SILVA, Luiz Antônio Franco dahttp://lattes.cnpq.br/0446055905975647FIORAVANTI, Maria Clorinda Soareshttp://lattes.cnpq.br/8772502020076257http://lattes.cnpq.br/9636259477810298MOURA, Maria Ivete de2014-07-29T15:13:42Z2011-11-012011-03-18MOURA, Maria Ivete de. Digital dermatitis disease bovine: genetic and therapeutic aspects. 2011. 113 f. Tese (Doutorado em Ciências Agrárias) - Universidade Federal de Goiás, Goiânia, 2011.http://repositorio.bc.ufg.br/tede/handle/tde/1121This study has aimed do evaluate a risk factor for bovine digital dermatitis and the efficacy of 5% aqueous barbatimão extract solution as ancillary in interdigital skin incisional wound repair. One hundred bovine females, 50 Holstein and 50 Girolando, from two different farms were used for the risk factor study. Experimental units were divided into four groups: healthy Holstein cattle group (GHS) and digital dermatitis Holstein cattle group (GHL), healthy Girolando cattle group (GGS) and digital dermatitis Girolando cattle group (GGL). Ten milliliters of blood were collected from all animals and stored in anticoagulant added tubes. Samples were refrigerated and submitted to hemolytic tests for eight bovine blood systems: A, B, C, F, J, L, S and Z. The frequency of blood factors was determined and compared, in each system and each group. Data were analyzed through non parametric tests: Chi Square and Fisher s exact. The results indicated that the blood factors may contribute to the occurrence of digital dermatitis lesions, but further studies are needed for a more accurate conclusion. Thirty confined, 10 months old calves were selected in order to evaluate the efficacy of 5% barbatimão solution. A biopsy punch was introduced in each interdigital space, up to the dermis, to produce a lesion measuring one centimeter in diameter. The lesions were numbered 120 in total and named experimental units, which were divided into two groups of 60 units each: GB treated with 5% aqueous barbatimão bark extract solution and GC treated with water. Tissue repair was evaluated through macroscopic and histological findings in days three, seven, 14 and 21 of treatment. Macroscopic findings were analyzed descriptively, while histological findings were submitted to Mann Whitney test, with p<0.05. For lesions treated, GB group showed less intense polymorphonuclear cells infiltration on the first 14 days of treatment. A marked collagen deposition was also observed at day 14 while collagen alignment was more expressive on day 21. More specific studies may be necessary in order to determine if blood factors can contribute to the occurrence of digital dermatitis. Barbatiman 5% footbath solution for confined cattle helps qualitatively in modulation of interdigital cutaneous incisional wound repair, but does not avoid the extension of inflammatory phase of healing.Objetivou-se nesta pesquisa estudar um fator de risco para a dermatite digital bovina e avaliar a eficácia do extrato de barbatimão em solução aquosa a 5% como auxiliar no reparo de feridas cutâneas induzidas no espaço interdigital de bovinos. Para pesquisar o fator de risco utilizaram-se 100 fêmeas bovinas, sendo 50 Holandesas e 50 Girolando, de duas propriedades rurais. Dividiram-se as unidades experimentais em quatro grupos: grupo de animais saudáveis da raça Holandesa (GHS) e grupo com lesões de dermatite digital (GHL); grupo de animais saudáveis da raça Girolando (GGS) e grupo com lesões de dermatite digital (GGL). De todos os animais colheram-se 10 ml de sangue, em tubo a vácuo, contendo anticoagulante. As amostras foram refrigeradas e submetidas a testes hemolíticos, para oito sistemas sanguíneos de bovinos: A, B, C, F, J, L, S e Z. A frequência dos fatores sanguíneos foi determinada e comparada, dentro de cada sistema, em cada grupo de animais. Os dados foram analisados através dos testes não paramétricos de Qui-quadrado e Exato de Fisher. Pelos resultados obtidos concluiu-se que os fatores sanguíneos podem contribuir para a ocorrência de lesões de dermatite digital, contudo são necessários estudos mais específicos para uma conclusão mais precisa. Para avaliar a eficácia da solução de barbatimão a 5%, utilizaram-se 30 animais com dez meses de idade, mantidos em sistema de confinamento. Em cada espaço interdigital dos animais, com auxílio de um punch de um centímetro de diâmetro, produziu-se uma lesão cutânea até a derme, totalizando 120 feridas. As feridas foram denominadas unidades experimentais e distribuídas em dois grupos com 60 unidades cada: grupo GB tratado com solução de extrato de barbatimão a 5% e grupo GC tratado com água. A evolução do processo de reparação tecidual das feridas foi acompanhada por meio de avaliações macroscópicas e histológicas nos dias três, sete, 14 e 21 de tratamento. Os achados macroscópicos foram analisados descritivamente e os histológicos submetidos ao teste de Mann Whitney, com p<0,05. Para as feridas tratadas, observou-se que o grupo GB apresentou menor intensidade de infiltrado de células polimorfonucleares nos primeiros 14 dias de tratamento. Nesse grupo observou-se ainda que a deposição de colágeno mostrou-se mais acentuada aos 14 dias e aos 21 dias as fibras colágenas apresentavam-se mais alinhadas. O uso do extrato de barbatimão a 5% em pedilúvio, em bovinos confinados, auxiliou qualitativamente no processo de modulação da reparação de feridas cutâneas interdigitais incisionais, mas não impediu o prolongamento da fase inflamatória do processo cicatricial.Made available in DSpace on 2014-07-29T15:13:42Z (GMT). No. of bitstreams: 1 tese pos defesa.pdf: 2322225 bytes, checksum: 4027ee4b5a7e38a6c0d20eb192a18551 (MD5) Previous issue date: 2011-03-18application/pdfhttp://repositorio.bc.ufg.br/TEDE/retrieve/4045/tese%20pos%20defesa.pdf.jpgporUniversidade Federal de GoiásDoutorado em Ciência AnimalUFGBRCiências AgráriasBarbatimãobovinosdermatite digitalfator sanguíneopedilúvioterapêuticaBarbatimãobovinedigital dermatitisblood factorfootbaththerapeuticsCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMALEnfermidades Cutâneas Digitais Bovina: Aspectos Genéticos E TerapêuticosDigital dermatitis disease bovine: genetic and therapeutic aspectsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGORIGINALtese pos defesa.pdfapplication/pdf2322225http://repositorio.bc.ufg.br/tede/bitstreams/198a31cc-309e-43af-ac8a-9e84f5946f04/download4027ee4b5a7e38a6c0d20eb192a18551MD51THUMBNAILtese pos defesa.pdf.jpgtese pos defesa.pdf.jpgGenerated Thumbnailimage/jpeg1943http://repositorio.bc.ufg.br/tede/bitstreams/fc91983d-a78f-45a1-8182-7ff36fab8387/downloadcc73c4c239a4c332d642ba1e7c7a9fb2MD52tde/11212014-07-30 03:10:36.553open.accessoai:repositorio.bc.ufg.br:tde/1121http://repositorio.bc.ufg.br/tedeBiblioteca Digital de Teses e Dissertaçõeshttp://repositorio.bc.ufg.br/PUBhttps://repositorio.bc.ufg.br/tede_oai/requesttesesdissertacoes.bc@ufg.br ||tesesdissertacoes.bc@ufg.bropendoar:32082014-07-30T06:10:36Biblioteca Digital de Teses e Dissertações da UFG - Universidade Federal de Goiás (UFG)false |
dc.title.por.fl_str_mv |
Enfermidades Cutâneas Digitais Bovina: Aspectos Genéticos E Terapêuticos |
dc.title.alternative.eng.fl_str_mv |
Digital dermatitis disease bovine: genetic and therapeutic aspects |
title |
Enfermidades Cutâneas Digitais Bovina: Aspectos Genéticos E Terapêuticos |
spellingShingle |
Enfermidades Cutâneas Digitais Bovina: Aspectos Genéticos E Terapêuticos MOURA, Maria Ivete de Barbatimão bovinos dermatite digital fator sanguíneo pedilúvio terapêutica Barbatimão bovine digital dermatitis blood factor footbath therapeutics CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL |
title_short |
Enfermidades Cutâneas Digitais Bovina: Aspectos Genéticos E Terapêuticos |
title_full |
Enfermidades Cutâneas Digitais Bovina: Aspectos Genéticos E Terapêuticos |
title_fullStr |
Enfermidades Cutâneas Digitais Bovina: Aspectos Genéticos E Terapêuticos |
title_full_unstemmed |
Enfermidades Cutâneas Digitais Bovina: Aspectos Genéticos E Terapêuticos |
title_sort |
Enfermidades Cutâneas Digitais Bovina: Aspectos Genéticos E Terapêuticos |
author |
MOURA, Maria Ivete de |
author_facet |
MOURA, Maria Ivete de |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
SILVA, Luiz Antônio Franco da |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/0446055905975647 |
dc.contributor.advisor-co1.fl_str_mv |
FIORAVANTI, Maria Clorinda Soares |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/8772502020076257 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/9636259477810298 |
dc.contributor.author.fl_str_mv |
MOURA, Maria Ivete de |
contributor_str_mv |
SILVA, Luiz Antônio Franco da FIORAVANTI, Maria Clorinda Soares |
dc.subject.por.fl_str_mv |
Barbatimão bovinos dermatite digital fator sanguíneo pedilúvio terapêutica |
topic |
Barbatimão bovinos dermatite digital fator sanguíneo pedilúvio terapêutica Barbatimão bovine digital dermatitis blood factor footbath therapeutics CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL |
dc.subject.eng.fl_str_mv |
Barbatimão bovine digital dermatitis blood factor footbath therapeutics |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL |
description |
This study has aimed do evaluate a risk factor for bovine digital dermatitis and the efficacy of 5% aqueous barbatimão extract solution as ancillary in interdigital skin incisional wound repair. One hundred bovine females, 50 Holstein and 50 Girolando, from two different farms were used for the risk factor study. Experimental units were divided into four groups: healthy Holstein cattle group (GHS) and digital dermatitis Holstein cattle group (GHL), healthy Girolando cattle group (GGS) and digital dermatitis Girolando cattle group (GGL). Ten milliliters of blood were collected from all animals and stored in anticoagulant added tubes. Samples were refrigerated and submitted to hemolytic tests for eight bovine blood systems: A, B, C, F, J, L, S and Z. The frequency of blood factors was determined and compared, in each system and each group. Data were analyzed through non parametric tests: Chi Square and Fisher s exact. The results indicated that the blood factors may contribute to the occurrence of digital dermatitis lesions, but further studies are needed for a more accurate conclusion. Thirty confined, 10 months old calves were selected in order to evaluate the efficacy of 5% barbatimão solution. A biopsy punch was introduced in each interdigital space, up to the dermis, to produce a lesion measuring one centimeter in diameter. The lesions were numbered 120 in total and named experimental units, which were divided into two groups of 60 units each: GB treated with 5% aqueous barbatimão bark extract solution and GC treated with water. Tissue repair was evaluated through macroscopic and histological findings in days three, seven, 14 and 21 of treatment. Macroscopic findings were analyzed descriptively, while histological findings were submitted to Mann Whitney test, with p<0.05. For lesions treated, GB group showed less intense polymorphonuclear cells infiltration on the first 14 days of treatment. A marked collagen deposition was also observed at day 14 while collagen alignment was more expressive on day 21. More specific studies may be necessary in order to determine if blood factors can contribute to the occurrence of digital dermatitis. Barbatiman 5% footbath solution for confined cattle helps qualitatively in modulation of interdigital cutaneous incisional wound repair, but does not avoid the extension of inflammatory phase of healing. |
publishDate |
2011 |
dc.date.available.fl_str_mv |
2011-11-01 |
dc.date.issued.fl_str_mv |
2011-03-18 |
dc.date.accessioned.fl_str_mv |
2014-07-29T15:13:42Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MOURA, Maria Ivete de. Digital dermatitis disease bovine: genetic and therapeutic aspects. 2011. 113 f. Tese (Doutorado em Ciências Agrárias) - Universidade Federal de Goiás, Goiânia, 2011. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tde/1121 |
identifier_str_mv |
MOURA, Maria Ivete de. Digital dermatitis disease bovine: genetic and therapeutic aspects. 2011. 113 f. Tese (Doutorado em Ciências Agrárias) - Universidade Federal de Goiás, Goiânia, 2011. |
url |
http://repositorio.bc.ufg.br/tede/handle/tde/1121 |
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por |
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UFG |
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BR |
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Ciências Agrárias |
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Universidade Federal de Goiás |
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