Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFLA |
Texto Completo: | http://repositorio.ufla.br/jspui/handle/1/29864 |
Resumo: | Leaves of Psidium guajava L. (guava) have been widely used in the popular way for prevention and treatment of various diseases. Thus, the objective of this study was to evaluate the inhibitory potential of leaves aqueous extract from three cultivars of P. guajava (Pedro Sato, Paluma and Século XXI) on α-amylase, α-glycosidase, lipase, and trypsin enzymes, in the presence or not of simulated gastric fluid and to determine the content of phenolic compounds by high performance liquid chromatography. All cultivars presented the same composition in phenolic compounds, but in different proportions. The compounds identified are gallic acid, epigallocatechin gallate, syringic acid, o-coumaric acid, resveratrol, quercetin, and catechin (which was the major compound in all the cultivars evaluated). In the absence of simulated gastric fluid, it was observed different inhibitions exercised by the leaves aqueous extracts from three cultivars of P. guajava on each enzyme. In presence of simulated gastric fluid, all cultivars showed increase in the inhibition of lipase and α-glycosidase, and decrease in inhibition of α-amylase and trypsin enzymes. These results indicate that P. guajava leaves aqueous extracts from all cultivars evaluated possess potential of use as an adjuvant in the treatment of obesity and other dyslipidemias. |
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Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymesMedicinal plantsObesityα-amylaseα-glycosidaseLipaseTrypsinLeaves of Psidium guajava L. (guava) have been widely used in the popular way for prevention and treatment of various diseases. Thus, the objective of this study was to evaluate the inhibitory potential of leaves aqueous extract from three cultivars of P. guajava (Pedro Sato, Paluma and Século XXI) on α-amylase, α-glycosidase, lipase, and trypsin enzymes, in the presence or not of simulated gastric fluid and to determine the content of phenolic compounds by high performance liquid chromatography. All cultivars presented the same composition in phenolic compounds, but in different proportions. The compounds identified are gallic acid, epigallocatechin gallate, syringic acid, o-coumaric acid, resveratrol, quercetin, and catechin (which was the major compound in all the cultivars evaluated). In the absence of simulated gastric fluid, it was observed different inhibitions exercised by the leaves aqueous extracts from three cultivars of P. guajava on each enzyme. In presence of simulated gastric fluid, all cultivars showed increase in the inhibition of lipase and α-glycosidase, and decrease in inhibition of α-amylase and trypsin enzymes. These results indicate that P. guajava leaves aqueous extracts from all cultivars evaluated possess potential of use as an adjuvant in the treatment of obesity and other dyslipidemias.Academia Brasileira de Ciências2018-08-01T20:04:42Z2018-08-01T20:04:42Z2017info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfSIMÃO, A. A. et al. Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes. Anais da Academia Brasileira de Ciências, Rio de Janeiro, v. 89, n. 3, p. 2155-2165, 2017. Suplemento 3.http://repositorio.ufla.br/jspui/handle/1/29864Anais da Academia Brasileira de Ciênciasreponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessSimão, Anderson AssaidMarques, Tamara R.Marcussi, SilvanaCorrea, Angelita Duarteeng2018-08-01T20:04:42Zoai:localhost:1/29864Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2018-08-01T20:04:42Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false |
dc.title.none.fl_str_mv |
Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes |
title |
Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes |
spellingShingle |
Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes Simão, Anderson Assaid Medicinal plants Obesity α-amylase α-glycosidase Lipase Trypsin |
title_short |
Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes |
title_full |
Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes |
title_fullStr |
Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes |
title_full_unstemmed |
Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes |
title_sort |
Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes |
author |
Simão, Anderson Assaid |
author_facet |
Simão, Anderson Assaid Marques, Tamara R. Marcussi, Silvana Correa, Angelita Duarte |
author_role |
author |
author2 |
Marques, Tamara R. Marcussi, Silvana Correa, Angelita Duarte |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Simão, Anderson Assaid Marques, Tamara R. Marcussi, Silvana Correa, Angelita Duarte |
dc.subject.por.fl_str_mv |
Medicinal plants Obesity α-amylase α-glycosidase Lipase Trypsin |
topic |
Medicinal plants Obesity α-amylase α-glycosidase Lipase Trypsin |
description |
Leaves of Psidium guajava L. (guava) have been widely used in the popular way for prevention and treatment of various diseases. Thus, the objective of this study was to evaluate the inhibitory potential of leaves aqueous extract from three cultivars of P. guajava (Pedro Sato, Paluma and Século XXI) on α-amylase, α-glycosidase, lipase, and trypsin enzymes, in the presence or not of simulated gastric fluid and to determine the content of phenolic compounds by high performance liquid chromatography. All cultivars presented the same composition in phenolic compounds, but in different proportions. The compounds identified are gallic acid, epigallocatechin gallate, syringic acid, o-coumaric acid, resveratrol, quercetin, and catechin (which was the major compound in all the cultivars evaluated). In the absence of simulated gastric fluid, it was observed different inhibitions exercised by the leaves aqueous extracts from three cultivars of P. guajava on each enzyme. In presence of simulated gastric fluid, all cultivars showed increase in the inhibition of lipase and α-glycosidase, and decrease in inhibition of α-amylase and trypsin enzymes. These results indicate that P. guajava leaves aqueous extracts from all cultivars evaluated possess potential of use as an adjuvant in the treatment of obesity and other dyslipidemias. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017 2018-08-01T20:04:42Z 2018-08-01T20:04:42Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
SIMÃO, A. A. et al. Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes. Anais da Academia Brasileira de Ciências, Rio de Janeiro, v. 89, n. 3, p. 2155-2165, 2017. Suplemento 3. http://repositorio.ufla.br/jspui/handle/1/29864 |
identifier_str_mv |
SIMÃO, A. A. et al. Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes. Anais da Academia Brasileira de Ciências, Rio de Janeiro, v. 89, n. 3, p. 2155-2165, 2017. Suplemento 3. |
url |
http://repositorio.ufla.br/jspui/handle/1/29864 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
dc.source.none.fl_str_mv |
Anais da Academia Brasileira de Ciências reponame:Repositório Institucional da UFLA instname:Universidade Federal de Lavras (UFLA) instacron:UFLA |
instname_str |
Universidade Federal de Lavras (UFLA) |
instacron_str |
UFLA |
institution |
UFLA |
reponame_str |
Repositório Institucional da UFLA |
collection |
Repositório Institucional da UFLA |
repository.name.fl_str_mv |
Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA) |
repository.mail.fl_str_mv |
nivaldo@ufla.br || repositorio.biblioteca@ufla.br |
_version_ |
1784550018896625664 |