Hematological, biochemical and anatomopathological aspects of the experimental infection with Trypanosoma evansi in dogs
Autor(a) principal: | |
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Data de Publicação: | 2002 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352002000100002 |
Resumo: | The course of experimental T. evansi infection in four dogs was followed for 82 days and hematological, biochemical and anatomopathological findings were studied. Infected animals showed progressive decrease in red blood cell count and hemoglobin concentration, leading to anemia which persisted from the third week post-infection until the end of the study. Leucopenia and neutropenia were observed between weeks 2 and 5 of the infection. The infected dogs developed hyperproteinemia and a decrease in the albumin:globulin ratio was observed. Aspartate aminotransferase and alamine aminotransferase levels increased significantly in infected dogs in comparison to control dogs. Histological changes observed in all infected animals consisted of lymphoid hyperplasia in spleens and lymph nodes and centrilobular degeneration and periportal mononuclear cell accumulation in the liver. A massive mononuclear cell infiltration of the myocardium was seen in three dogs and a nonsuppurative meningoencephalitis was evidente in two infected animals. |
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Hematological, biochemical and anatomopathological aspects of the experimental infection with Trypanosoma evansi in dogsDogTrypanosoma evansihematologybiochemistryanatomopathologyThe course of experimental T. evansi infection in four dogs was followed for 82 days and hematological, biochemical and anatomopathological findings were studied. Infected animals showed progressive decrease in red blood cell count and hemoglobin concentration, leading to anemia which persisted from the third week post-infection until the end of the study. Leucopenia and neutropenia were observed between weeks 2 and 5 of the infection. The infected dogs developed hyperproteinemia and a decrease in the albumin:globulin ratio was observed. Aspartate aminotransferase and alamine aminotransferase levels increased significantly in infected dogs in comparison to control dogs. Histological changes observed in all infected animals consisted of lymphoid hyperplasia in spleens and lymph nodes and centrilobular degeneration and periportal mononuclear cell accumulation in the liver. A massive mononuclear cell infiltration of the myocardium was seen in three dogs and a nonsuppurative meningoencephalitis was evidente in two infected animals.Universidade Federal de Minas Gerais, Escola de Veterinária2002-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352002000100002Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.54 n.1 2002reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/S0102-09352002000100002info:eu-repo/semantics/openAccessAquino,L.P.C.T.Machado,R.Z.Alessi,A.C.Santana,A.E.Castro,M.B.Marques,L.C.Malheiros,E.B.eng2002-07-22T00:00:00Zoai:scielo:S0102-09352002000100002Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2002-07-22T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false |
dc.title.none.fl_str_mv |
Hematological, biochemical and anatomopathological aspects of the experimental infection with Trypanosoma evansi in dogs |
title |
Hematological, biochemical and anatomopathological aspects of the experimental infection with Trypanosoma evansi in dogs |
spellingShingle |
Hematological, biochemical and anatomopathological aspects of the experimental infection with Trypanosoma evansi in dogs Aquino,L.P.C.T. Dog Trypanosoma evansi hematology biochemistry anatomopathology |
title_short |
Hematological, biochemical and anatomopathological aspects of the experimental infection with Trypanosoma evansi in dogs |
title_full |
Hematological, biochemical and anatomopathological aspects of the experimental infection with Trypanosoma evansi in dogs |
title_fullStr |
Hematological, biochemical and anatomopathological aspects of the experimental infection with Trypanosoma evansi in dogs |
title_full_unstemmed |
Hematological, biochemical and anatomopathological aspects of the experimental infection with Trypanosoma evansi in dogs |
title_sort |
Hematological, biochemical and anatomopathological aspects of the experimental infection with Trypanosoma evansi in dogs |
author |
Aquino,L.P.C.T. |
author_facet |
Aquino,L.P.C.T. Machado,R.Z. Alessi,A.C. Santana,A.E. Castro,M.B. Marques,L.C. Malheiros,E.B. |
author_role |
author |
author2 |
Machado,R.Z. Alessi,A.C. Santana,A.E. Castro,M.B. Marques,L.C. Malheiros,E.B. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Aquino,L.P.C.T. Machado,R.Z. Alessi,A.C. Santana,A.E. Castro,M.B. Marques,L.C. Malheiros,E.B. |
dc.subject.por.fl_str_mv |
Dog Trypanosoma evansi hematology biochemistry anatomopathology |
topic |
Dog Trypanosoma evansi hematology biochemistry anatomopathology |
description |
The course of experimental T. evansi infection in four dogs was followed for 82 days and hematological, biochemical and anatomopathological findings were studied. Infected animals showed progressive decrease in red blood cell count and hemoglobin concentration, leading to anemia which persisted from the third week post-infection until the end of the study. Leucopenia and neutropenia were observed between weeks 2 and 5 of the infection. The infected dogs developed hyperproteinemia and a decrease in the albumin:globulin ratio was observed. Aspartate aminotransferase and alamine aminotransferase levels increased significantly in infected dogs in comparison to control dogs. Histological changes observed in all infected animals consisted of lymphoid hyperplasia in spleens and lymph nodes and centrilobular degeneration and periportal mononuclear cell accumulation in the liver. A massive mononuclear cell infiltration of the myocardium was seen in three dogs and a nonsuppurative meningoencephalitis was evidente in two infected animals. |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352002000100002 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352002000100002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-09352002000100002 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
dc.source.none.fl_str_mv |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.54 n.1 2002 reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online) instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
instname_str |
Universidade Federal de Minas Gerais (UFMG) |
instacron_str |
UFMG |
institution |
UFMG |
reponame_str |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
collection |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) |
repository.name.fl_str_mv |
Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG) |
repository.mail.fl_str_mv |
journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br |
_version_ |
1750220877054607360 |